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Novel use of formaldehyde in preparation of drug for animals

A substance and formaldehyde technology, which is applied to the new use field of substance formaldehyde in the preparation of animal medicines, can solve the problems of drug residues and uncertain drug effects, and achieve the effects of no drug residues, no drug resistance, and strong after-effects.

Inactive Publication Date: 2007-10-17
关中田
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0009] In the application involved in the present invention, the current method for preventing and treating diseases caused by pathogenic microorganisms through the digestive tract infection is to use vaccine immunization and administer virucidal drugs and antibiotics, because the currently used vaccines need a certain period of time to achieve immunity after entering the body. and many of the above-mentioned diseases have no vaccines available so far. The effect of the virus-killing drugs currently used in the prevention and treatment of viral diseases is not reliable; the use of antibiotics in the prevention and treatment of bacterial diseases also has drug-resistant and sensitive drug residues And other issues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0053] Reference Example 2: Paraformaldehyde prevents sheep epidemic and sheep enterotoxemia

[0054] Test drug:

[0055] Paraformaldehyde, containing formaldehyde ≥ 97%. Heilongjiang Animal Husbandry and Veterinary Vocational College Veterinary Drug Factory Production Product Batch No. 20020801

[0056] Control drug: 10% lime water.

[0057] Test sheep:

[0058] In 2001 and 2003, the natural flock of sheep who came to the inventor's place for medical treatment. These flocks were not immunized with sheep rapid disease and sheep enterotoxemia vaccine (Clostridium ammonium three-in-one four-proof vaccine) in that year. The number of sheep in stock, body condition, feeding and grazing environment, morbidity rate, and mortality rate of sheep diagnosed as sheep epidemic disease or / and sheep enterotoxemia by methods such as science, clinical symptoms, laboratory diagnosis, and autopsy Basically similar. The natural flocks of the above sheep groups without clinical symptoms wer...

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Abstract

Provided is a novel use of formaldehyde in preparing pharmaceuticals for prevention and cure of animal diseases caused by pathogenic microorganisms through infection of digestive canal by means of digestive tract administration, wherein formaldehyde can deactivate pathogenic microorganisms and their toxins, make it lose pathogenicity while keeping the antigenicity. The invention realizes the advantages of broad spectrum, quick and sure effects, small dosage, less administration, lower price and removal of drug resistance and medicinal residual produced by the application of antibiotics.

Description

【Technical field】 [0001] The invention relates to a new application of a substance in the preparation of animal medicines. In particular, it relates to the new application of formaldehyde in the preparation of medicines administered through the digestive tract to prevent and treat diseases of animals caused by pathogenic microorganisms infected through the digestive tract. 【Background technique】 [0002] Formaldehyde substances include formaldehyde, its aqueous solutions formalin and paraformaldehyde, all of which are known animal drugs. Formaldehyde mainly has the following characteristics and purposes in the technical field of the present invention: [0003] Formaldehyde is a strong alkylating agent, which has a strong killing effect on pathogenic microorganisms such as bacteria, spores, fungi and viruses and their toxins. 0.005%-0.0125% formaldehyde solution can inhibit the reproduction of bacteria, 05% Formaldehyde solution can inactivate viruses and toxins, and 0.5-1%...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/115A61P31/00
Inventor 关中田
Owner 关中田
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