Nanoemulsion of liposoluble vitamin and preparation method thereof
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A fat-soluble vitamin and vitamin technology, which is used in medical preparations containing active ingredients, pharmaceutical formulas, emulsion delivery, etc.
Inactive Publication Date: 2011-06-15
上海恒丰强生物技术有限公司
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[0006] As we all know, vitamins are divided into fat-soluble and water-soluble according to their solubility in water, and fat-soluble vitamins are difficult to dissolve in water, and the utilization rate in feed is low. low bioavailability
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Embodiment 1
[0023] A kind of fat-soluble vitamin nanoemulsion is made by following method
[0024] Step (1): Take 15 ml of polyoxyethylene ether castor oil, heat it to 60 degrees, add 2 million IU of vitamin A acetate, and stir to dissolve;
[0025] Step (2): Then add vitamin D 1 million IU, stir for 2 minutes to dissolve,
[0026] Step (3): Then add vitamin E acetate 1000IU, stir for 2 minutes to dissolve,
[0027] Step (4): Add water to 100ml, stir until dissolved.
Embodiment 2
[0029] A kind of fat-soluble vitamin nanoemulsion is made by following method
[0030] Step (1): Take 10 ml of polyoxyethylene ether castor oil, heat it to 60 degrees, add 500,000 IU of vitamin A acetate, and stir to dissolve;
[0031] Step (2): Then add 250,000 IU of vitamin D, stir for 2 minutes to dissolve,
[0032] Step (3): Then add vitamin E acetate 500IU, stir for 2 minutes to dissolve,
[0033] Step (4): Add water to 100ml, stir until dissolved.
Embodiment 3
[0035] A kind of fat-soluble vitamin nanoemulsion is made by following method
[0036] Step (1): Take 10 ml of polyoxyethylene ether castor oil, heat it to 60 degrees, add 500,000 IU of vitamin A acetate, and stir to dissolve;
[0037] Step (2): Then add 250,000 IU of vitamin D, stir for 2 minutes to dissolve,
[0038] Step (3): Then add vitamin E acetate 500IU, stir for 2 minutes to dissolve,
[0039] Step (4): Add water to 100ml, stir until dissolved.
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Abstract
The invention relates to a nanoemulsion of liposoluble vitamin and a preparation method thereof. The nanoemulsion comprises the components by mass proportions: 0.5-4 million IU (International Unit) of vitamin A acetate, 0.25-1.5 million IU of vitamin D, 200-2000 IU of vitamin E acetate and 5-20ml of polyoxyethylene ether castor oil and 100ml of water. The preparation method of the nanoemulsion comprises the steps of: taking 15ml of polyoxyethylene ether castor oil, heating to 60 DEG C, adding the vitamin A acetate, and stirring until dissolving; then adding the vitamin D, and stirring until dissolving; then adding the vitamin E acetate, and stirring until dissolving; and adding water until 100ml, and stirring until clarifying.
Description
technical field [0001] The invention relates to a nanoemulsion of fat-soluble vitamins and a preparation method thereof. technical background [0002] [0003] About 90 years ago, a phenomenon was discovered in animal feeding experiments, that is, pure CH 2 O, protein, fat, and inorganic salts can only live for a short time, but adding a small amount of milk to these feeds can prolong the survival time, and it is concluded that milk contains essential nutrients that people did not know in the past. Soon, people realized that it contained at least two factors, fat-soluble factor A and water-soluble factor B. Later, people separated factor A and factor B, carried out chemical identification, and finally named it vitamin. [0004] Vitamins are organic substances that are indispensable for maintaining health and promoting growth. Poultry requires little amount of it, usually in mg. Each vitamin has its special function, neither an energy substance nor a structural substance f...
Claims
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