A kind of preparation method of special chromatographic separation medium for separation of fullerene and its derivatives

Abstract

The invention relates to a method for preparing a special chromatographic separation medium for the separation of fullerenes and their derivatives, which is characterized in that the specific steps are: (1) adding 5-50 g of porous amino silicon spheres to 50-500 mL of toluene, Stir to make it wet and disperse evenly; (2) Add 4-40g of pyrenecaproic acid to the toluene suspended with porous amino silicon balls, stir and mix evenly; (3) Add a condensing agent, React for 24 hours, filter; (4) add bonded silicon spheres to 50-500 mL of toluene again, and add 10-100 g of pentabromobenzyl bromide, react at 80 ° C for 24 hours, filter; (5) 50-500 mL of toluene Wash three times and dry at 80°C to obtain a chromatographic separation medium. The performance of the chromatographic separation medium bonded with two groups of the present invention is better than that of a single group in terms of bonding density and separation selectivity, especially the preparation capacity is larger, which can significantly improve the preparation efficiency.

Description

[0001] 【Technical field】 [0002] The invention relates to the technical field of chromatographic separation media, in particular to a preparation method of a special chromatographic separation medium for the separation of fullerenes and their derivatives. [0003] 【Background technique】 [0004] Fullerenes and their various derivatives have been successively developed. Usually, the activity and effect of fullerene derivatives are better than that of a single fullerene, which is the main reason why new fullerene derivatives, including metal fullerenes, have become research hotspots. However, due to the similarity of their structures, the separation analysis and separation and purification of these compounds have also brought great problems. [0005] As there are more and more derivatives of fullerene, the difficulty of separation is also increasing. The traditional single-bonded packing can no longer meet the current separation requirements, so we now bond pyrene and pentabrom...

AI Technical Summary

Problems solved by technology

However, due to the similarity of their structures, it also brings great problems to the separation analysis and separation and purification of these compounds.

[0005] As there are more and more derivatives of fullerene, the difficulty of separation is also increasing. The traditional single-bonded packing can no longer meet the current separation requirements, so we now bond pyrene and pentabromobenzene in two parts. on the same silicon sphere

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