Cordyceps sinensis-containing plant composition extraction method and application

A technology of Cordyceps sinensis and extraction method, which is applied to medical preparations containing active ingredients, medical raw materials derived from ferns/filamentous plants, and plant raw materials, etc. problem, to achieve the effect of reducing the dosage

Inactive Publication Date: 2016-02-24
NANJING ZHENGLIANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Cordyceps sinensis. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients, which is inconvenient to take and serious. Affected the clinical application of this product

Method used

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  • Cordyceps sinensis-containing plant composition extraction method and application

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Comparison scheme
Effect test

Embodiment 1

[0014] Take 70 parts of Cordyceps sinensis, 50 parts of Dajindao, 60 parts of Yanlaihong, 40 parts of Rowan, and 80 parts of Tongjinghua, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400- 600W, extract 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, Concentrate and dry to obtain a microwave extract, and add conventional excipients to prepare tablets, each tablet 0.4g.

Embodiment 2

[0016] Take 70 parts of Cordyceps sinensis, 50 parts of Dajindao, 60 parts of Yanlaihong, 40 parts of Rowan, and 80 parts of Tongjinghua, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400- 600W, extract 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, Concentrate and dry to obtain the microwave extract, and add conventional auxiliary materials to prepare capsules.

Embodiment 3

[0018] Take 70 parts of Cordyceps sinensis, 50 parts of Dajindao, 60 parts of Yanlaihong, 40 parts of Rowan, and 80 parts of Tongjinghua, grind them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400- 600W, extract 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, Concentrate and dry to obtain a microwave extract, and add conventional auxiliary materials to prepare granules.

[0019] Dajindao is the fern Neolepisorusovatus (Bedd.) Ching, which is used as medicine with whole grass or leaves. It can be collected in four seasons, washed and dried in the sun. Clearing away heat and promoting dampness, cooling blood for hemostasis. For urinary tract infection, dysuria, hemoptysis. External use to treat wound bleeding, burns and scalds. ...

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Abstract

The present invention provides a cordyceps sinensis-containing plant composition extraction method, a cordyceps sinensis-containing plant composition is prepared from 70 parts of cordyceps sinensis, 50 parts of neolepisorus ovatus, 60 parts of amaranthus tricolor, 40 parts of Sorbus pohuashanensis and 80 parts of Abelia engleriana (Graebn. ) Rehd as medicinal raw materials by microwave extraction method, the content is greatly improved, the use amount is reduced, and the present invention also provides application of the cordyceps sinensis-containing plant composition in manufacture of rat fibroblast cell line NIH / 3T3 proliferation suppressing drugs.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing Cordyceps sinensis. Background technique [0002] The plant composition containing Cordyceps sinensis is made of 70 parts of Cordyceps sinensis, 50 parts of Dajindao, 60 parts of Yanlaihong, 40 parts of Rowan, and 80 parts of Tongjinghua as raw materials. The current extraction method is to add water and decoct twice. After 2-3 hours, combine the decoction, filter, concentrate into a thick paste, granulate, dry, and coat with sugar. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Cordyceps sinensis. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients, which is inconvenient to take and serious. Affec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73
CPCA61K36/068A61K36/11A61K36/21A61K36/35A61K36/73A61K2236/333A61K2236/39A61K2236/55
Inventor 赵明亮
Owner NANJING ZHENGLIANG MEDICAL TECH
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