Enema preparation for treatment of diabetic nephropathy

Abstract

The present invention relates to an enema preparation for treatment of diabetic nephropathy, which can effectively solve the drug problem in diabetic nephropathy, the enema preparation comprises the following raw materials in parts by weight: 5-20 parts of Chinese angelica, 5-20 parts of white peony root, 5-15 parts of ligusticum wallichii, 5-20 parts of Poria, 5-25 parts of white atractylodes rhizome, 5-15 parts of alisma, 5-15 parts of betel nut, 5-15 parts of habenaria stenopetala, 10-50 parts of shepherd's purse, 5-30 parts of Chinese rhubarb, 5-15 parts of semen lepidii and 5-15 parts of fructus liquidambaris, the enema preparation can effectively improve the integral of clinical symptom and microalbumin excretion rate of patients with diabetic nephropathy, delays the progression of the course of disease of the diabetic nephropathy, and is an innovation on the drug for treatment of diabetic nephropathy.

Description

technical field

[0001] The invention relates to the field of medicine, in particular to an enema preparation for treating diabetic nephropathy. Background technique

[0002] Diabetic nephropathy (diabetic nephropathy, DN) is one of the common and serious chronic complications of diabetes, and it is also the main cause of death in diabetic patients. Diabetes lasts for 10-20 years, and the incidence of DN is 30%-50%. 50% of patients with clinical proteinuria will enter end-stage renal disease (ESRD) within about 7 years. Therefore, the prevention and treatment of DN is particularly important.

[0003] For the treatment of diabetic nephropathy, comprehensive measures such as blood sugar control and low-protein diet are currently adopted clinically. Patients with end-stage diabetic nephropathy need hemodialysis, peritoneal dialysis or kidney transplantation. Adherence is poor. Therefore, the improvement of drugs for the treatment of diabetic nephropathy is an urgent problem to...

Examples

Embodiment 1

[0009] When the present invention is implemented, it is made from the following raw materials in parts by weight: 6-12 parts of Angelica sinensis, 6-12 parts of Radix Paeoniae Alba, 6-9 parts of Rhizoma Chuanxiong, 6-12 parts of Poria cocos, 6-15 parts of Atractylodes macrocephala, 6-9 parts of Alisma, 6-9 parts of betel nut, 6-9 parts of chicken kidney grass, 11-29 parts of shepherd's purse, 6-17 parts of rhubarb, 6-9 parts of Tinglizi and 6-9 parts of Passepartout. The above raw materials and medicines are mixed together, submerged in water, decocted for 60-90 minutes, filtered to obtain a filtrate, which is an enema preparation for treating diabetic nephropathy.

Embodiment 2

[0011] When the present invention is implemented, it can be made from the following raw materials in parts by weight: 13-19 parts of Angelica sinensis, 13-19 parts of Radix Paeoniae Alba, 10-14 parts of Rhizoma Chuanxiong, 13-19 parts of Poria cocos, 16-24 parts of Atractylodes macrocephala, 10-14 parts of Alisma, 10-14 parts of betel nut, 10-14 parts of chicken kidney grass, 30-49 parts of shepherd's purse, 18-29 parts of rhubarb, 10-14 parts of Tinglizi and 10-14 parts of Passepartout. The above raw materials and medicines are mixed together, submerged in water, decocted for 60-90 minutes, filtered to obtain a filtrate, which is an enema preparation for treating diabetic nephropathy.

Embodiment 3

[0013] When the present invention is implemented, it can be made from the following raw materials in parts by weight: 6 parts of Angelica sinensis, 19 parts of Radix Paeoniae Alba, 6 parts of Rhizoma Chuanxiong, 19 parts of Poria cocos, 6 parts of Atractylodes macrocephala, 14 parts of Alisma, 6 parts of betel nut, chicken 14 parts of kidney grass, 11 parts of shepherd's purse, 29 parts of rhubarb, 6 parts of Tinglizi and 14 parts of Passepartout, mix the above raw materials together, add water to immerse, decoct for 60-90 minutes, filter, and get the filtrate, which is the treatment Enema preparations for diabetic nephropathy.

technical field

[0001] The invention relates to the field of medicine, in particular to an enema preparation for treating diabetic nephropathy. Background technique

[0002] Diabetic nephropathy (diabetic nephropathy, DN) is one of the common and serious chronic complications of diabetes, and it is also the main cause of death in diabetic patients. Diabetes lasts for 10-20 years, and the incidence of DN is 30%-50%. 50% of patients with clinical proteinuria will enter end-stage renal disease (ESRD) within about 7 years. Therefore, the prevention and treatment of DN is particularly important.

[0003] For the treatment of diabetic nephropathy, comprehensive measures such as blood sugar control and low-protein diet are currently adopted clinically. Patients with end-stage diabetic nephropathy need hemodialysis, peritoneal dialysis or kidney transplantation. Adherence is poor. Therefore, the improvement of drugs for the treatment of diabetic nephropathy is an urgent problem to...

Examples

Embodiment 1

[0009] When the present invention is implemented, it is made from the following raw materials in parts by weight: 6-12 parts of Angelica sinensis, 6-12 parts of Radix Paeoniae Alba, 6-9 parts of Rhizoma Chuanxiong, 6-12 parts of Poria cocos, 6-15 parts of Atractylodes macrocephala, 6-9 parts of Alisma, 6-9 parts of betel nut, 6-9 parts of chicken kidney grass, 11-29 parts of shepherd's purse, 6-17 parts of rhubarb, 6-9 parts of Tinglizi and 6-9 parts of Passepartout. The above raw materials and medicines are mixed together, submerged in water, decocted for 60-90 minutes, filtered to obtain a filtrate, which is an enema preparation for treating diabetic nephropathy.

Embodiment 2

[0011] When the present invention is implemented, it can be made from the following raw materials in parts by weight: 13-19 parts of Angelica sinensis, 13-19 parts of Radix Paeoniae Alba, 10-14 parts of Rhizoma Chuanxiong, 13-19 parts of Poria cocos, 16-24 parts of Atractylodes macrocephala, 10-14 parts of Alisma, 10-14 parts of betel nut, 10-14 parts of chicken kidney grass, 30-49 parts of shepherd's purse, 18-29 parts of rhubarb, 10-14 parts of Tinglizi and 10-14 parts of Passepartout. The above raw materials and medicines are mixed together, submerged in water, decocted for 60-90 minutes, filtered to obtain a filtrate, which is an enema preparation for treating diabetic nephropathy.

Embodiment 3

[0013] When the present invention is implemented, it can be made from the following raw materials in parts by weight: 6 parts of Angelica sinensis, 19 parts of Radix Paeoniae Alba, 6 parts of Rhizoma Chuanxiong, 19 parts of Poria cocos, 6 parts of Atractylodes macrocephala, 14 parts of Alisma, 6 parts of betel nut, chicken 14 parts of kidney grass, 11 parts of shepherd's purse, 29 parts of rhubarb, 6 parts of Tinglizi and 14 parts of Passepartout, mix the above raw materials together, add water to immerse, decoct for 60-90 minutes, filter, and get the filtrate, which is the treatment Enema preparations for diabetic nephropathy.