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A kit for simultaneous detection of sodium, creatinine and microalbumin in urine

A microalbumin and kit technology, which is applied in the field of medical testing and determination, can solve the problems of insufficient testing hardware in testing units, and achieve the effects of improving sensitivity and accuracy, simple and accurate collection of single urine

Active Publication Date: 2018-08-17
北京中生金域诊断技术股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no dry chemical kit or similar method that can detect sodium, creatinine and microalbumin in urine at the same time. There is an urgent need to provide a fast, simple, semi-quantitative detection kit for the semi-quantitative detection of sodium, creatinine and microalbumin in urine due to the insufficient detection hardware of the detection unit

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Embodiment 1 simultaneously detects the preparation of the dry chemical kit of urine sodium, creatinine and trace albumin

[0051] The kit for simultaneous detection of urinary sodium, creatinine and microalbumin in this embodiment includes: a reaction substrate with sodium reaction wells, creatinine reaction wells and microalbumin reaction wells; sodium diluent and creatinine diluent; sodium ions with different concentrations Standard color guides for standard color development, standard color development of different concentrations of creatinine and standard color development of different concentrations of microalbumin.

[0052] The preparation method of the above-mentioned simultaneous detection of urine sodium, creatinine and microalbumin test kit is as follows:

[0053] (1) The structure of the reaction substrate:

[0054] The reaction substrate of the present embodiment is selected from ABS engineering plastics and is provided with sodium reaction holes, creatini...

Embodiment 2

[0085] Embodiment 2 Application of the dry chemical kit capable of simultaneously detecting urine sodium, creatinine and microalbumin of the present invention

[0086] The kit of the present invention is a dry chemical kit for semi-quantitative detection of urine sodium, creatinine and microalbumin, which can detect clinically the urine samples of hypertensive patients, and can also detect the urine samples of healthy people. It can be used as an auxiliary indicator for the diagnosis, differential diagnosis and curative effect evaluation of hypertensive patients, and can also be used as an auxiliary tool for healthy people to control their salt intake in their daily diet.

[0087] The specific method of use of the kit prepared in Example 1 of the present invention is as follows:

[0088] 1) When in use, first take the kit out of the storage temperature, equilibrate to room temperature and start using;

[0089] 2) Tear off the aluminum foil packaging and take out the reaction ...

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Abstract

The invention provides a kit for simultaneously detecting sodium, creatinine and microalbumin in urine. The kit comprises a reaction substrate with a sodium reaction hole, a creatinine reaction hole and a microalbumin reaction hole, and sodium diluent, creatinine diluents and standard colorimetric plates for sodium, creatinine and albumin. Reaction mats containing different configuration substrates and enzyme solutions are added to the three reaction holes, and semiquantitative detection on sodium, creatinine and microalbumin in urine is achieved. The kit is simple in preparation method, stable in performance and easy to store, color gradations corresponding to the content of sodium, creatinine and microalbumin in different kinds of urine are obvious, whether the salt amount of a detected person exceeds the standard or not and whether the kidney is damaged or not can be conveniently judged, and meanwhile the kit is suitable for being used by the clinical laboratory in a hospital and non-professional inspection personnel.

Description

technical field [0001] The invention relates to a method for measuring sodium, creatinine and microalbumin in urine by an enzymatic method, and a dry chemical kit for simultaneously detecting urine sodium, creatinine and microalbumin prepared by using the method, which belongs to the medical examination and measurement technology field. Background technique [0002] Excessive intake of sodium can cause left ventricular hypertrophy, proteinuria, arteriosclerosis, etc., and plays an important role in the progression of end-stage renal failure. While reducing sodium intake, it can not only lower blood pressure, but also reduce the excretion of urinary protein. Sodium plays a central role in maintaining normal water distribution and osmotic pressure. The kidney is the main organ that regulates sodium and water and maintains acid-base balance. Sodium is freely filtered out by the kidneys, and most of it is reabsorbed. Urinary sodium excretion is also closely related to dietar...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/78G01N33/70G01N33/68
CPCG01N21/78G01N33/683G01N33/70
Inventor 孙宁玲王鸿懿王加义喜杨马志毅张丽梅陈源源王及华董婷婷王维韩伟中赵立超张志丽桂春爽杨路
Owner 北京中生金域诊断技术股份有限公司
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