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Traditional Chinese medicine and application of its extracted composition in treating gout

A technology of extracts and compositions, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as temporary cure, neurotoxicity, liver damage, etc., and achieve the best therapeutic effect and side effects low effect

Active Publication Date: 2017-12-29
林嗣松 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicines are mostly used in the treatment of gout, such as allopurinol, colchicine, glucocorticoids and other drugs, but long-term use of these chemical drugs will cause side effects such as liver damage, gastrointestinal reactions, and neurotoxicity, and they will not cure the symptoms

Method used

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  • Traditional Chinese medicine and application of its extracted composition in treating gout
  • Traditional Chinese medicine and application of its extracted composition in treating gout
  • Traditional Chinese medicine and application of its extracted composition in treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Chinese medicinal materials: 50g aconite, 200g gardenia, 200g chicory root, 100g toosendan, 100g plantain seed, 100g kudzu root

[0018] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extract, get Chinese medicine extract 32.5g (hereinafter referred to as product A); Wherein, extraction pressure is 25MPa, and extraction temperature is 45-50 ℃, CO 2 The flow rate is 50L / h, the extraction time is 2h, the temperature of the separation tank I is 40-45°C, and the pressure is 7MPa, and the temperature of the separation tank II is 35-40°C, and the pressure is 5MPa.

Embodiment 2

[0020] Chinese medicine decoction pieces: 200g aconite, 800g gardenia, 800g chicory root, 500g toosendan, 500g plantain seed, 600g kudzu root

[0021] Pulverize and mix the above-mentioned Chinese medicinal pieces to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extract, get Chinese medicine extract 143g (hereinafter referred to as product B); Wherein, extraction pressure is 30MPa, and extraction temperature is 45-50 ℃, CO 2 The flow rate is 60L / h, the extraction time is 3h, the temperature of the separation tank I is 40-45°C, and the pressure is 10MPa, and the temperature of the separation tank II is 35-40°C, and the pressure is 6MPa.

Embodiment 3

[0023] Chinese medicinal materials: 50g aconite, 800g gardenia, 200g chicory root, 100g toosendan, 500g plantain seed, 100g kudzu root

[0024] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extract, get Chinese medicine extract 78.3g (hereinafter referred to as product C); Wherein, extraction pressure is 30MPa, and extraction temperature is 45-50 ℃, CO 2 The flow rate is 55L / h, the extraction time is 2h, the temperature of the separation tank I is 40-45°C, and the pressure is 10MPa, and the temperature of the separation tank II is 35-40°C, and the pressure is 6MPa.

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Abstract

The invention relates to a traditional Chinese medicine and application of its extracted composition in treating gout, and particularly relates to a traditional Chinese medicine. The traditional Chinese medicine is characterized by being prepared from, by weight, 0.5-2 parts of radix aconiti lateralis prepared, 2-8 parts of jasmine, 2-8 parts of endive root, 1-5 parts of szechwan Chinaberry fruit, 1-5 parts of semen plantaginis, and 1-6 parts of pueraria. The function of traditional Chinese medicine and its extractive in treating hyperuricemia and acute gout arthritis is better than allopurinol and colchicine; moreover, the toxic and side effects are low.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to the application of a traditional Chinese medicine and its extract composition in treating gout. Background technique [0002] Gout is a systemic disease caused by purine metabolism disorder, and the most important biochemical basis is hyperuricemia. Due to the increase of uric acid in serum and body fluids, urate crystals are deposited in various mesenchymal tissues. When joints are involved, it is called gouty arthritis. At present, Western medicines are mostly used in the treatment of gout, such as allopurinol, colchicine, glucocorticoids and other drugs. However, long-term use of these chemical drugs will cause side effects such as liver damage, gastrointestinal reactions, and neurotoxicity, and the symptoms are not cured. Therefore be badly in need of developing a kind of medicine that therapeutic effect is good, toxic and side effect is little. Cont...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61P19/06A61P19/02
CPCA61K36/28A61K36/488A61K36/58A61K36/68A61K36/714A61K36/744A61K2236/37A61K2300/00
Inventor 林嗣松王四旺
Owner 林嗣松
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