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Circular type biological membrane with cross-shaped section

A biofilm, cross-shaped technology, used in medical science, surgery, etc., can solve the problems of biocomposite film degradation speed time performance indicators that cannot meet clinical needs, cannot be effectively fitted, and the fracture area is small.

Inactive Publication Date: 2018-03-09
锡山区东港晓鸣电子产品经营部
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together
[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

Method used

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  • Circular type biological membrane with cross-shaped section
  • Circular type biological membrane with cross-shaped section

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] refer to figure 1 , 2 Circular biofilm 1 with a cross-shaped cross-section, including a hollow biofilm folded into a cross-shaped cross-section, with four vertex angles of "U", and the vertex angles coincide with the fracture line section, and the inner layer of the biofilm is an elastic layer The outer layer is a drug layer and an elastic layer, which is a dense degradable or non-degradable biofilm. The material of the drug layer is a degradable or non-degradable, absorbent or non-absorbable or porous material that is biocompatible with human bone. Drugs that can promote bone healing are also encapsulated inside the drug layer. After the circular biofilm 1 with a cross-section is cut, four "U"-shaped unit biofilms 2 are formed.

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Abstract

Circular biofilm with a cross-section, including a hollow biofilm folded into a cross-section, with four corners as "U", and the top corners coincide with the fracture line section. The inner layer of the biofilm is an elastic layer, and the outer layer is The layer is a drug layer and an elastic layer, which is a dense degradable or non-degradable biofilm. The material of the drug layer is a degradable or non-degradable, absorbent or non-absorbable or porous material that is biocompatible with human bone. The drug layer Medicines that can promote bone healing are also encapsulated inside.

Description

technical field [0001] The present invention relates to a circular biofilm with cross-section. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, and prevents the reaction of human ti...

Claims

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Application Information

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IPC IPC(8): A61L31/12A61L31/06A61L31/04A61L31/02A61L31/00A61L31/14A61L31/16
CPCA61L31/06A61L31/005A61L31/024A61L31/04A61L31/042A61L31/044A61L31/046A61L31/14A61L31/146A61L31/148A61L31/16A61L2300/108A61L2300/232A61L2300/252A61L2300/30A61L2300/412A61L2300/414A61L2300/602A61L2300/604C08L67/04C08L1/02
Inventor 王全宝
Owner 锡山区东港晓鸣电子产品经营部
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