System of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients

A technology for syndrome and liver cirrhosis, applied in the field of medicine, can solve problems such as the lack of short-term prognosis judgment methods for patients with liver cirrhosis and hepatorenal syndrome, and achieve the effect of prolonging survival time

Active Publication Date: 2018-08-17
BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIV
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Problems solved by technology

However, there is still a lack of a more effective method for judging the short-ter

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  • System of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients
  • System of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients
  • System of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients

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Embodiment 1

[0027] A retrospective collection of 362 patients with liver cirrhosis and hepatorenal syndrome diagnosed from January 2013 to December 2014, 62 patients with primary kidney disease were excluded, 52 patients with incomplete clinical data, and 246 patients were finally eligible for enrollment standard. 196 patients with hepatorenal syndrome were used for modeling, of which 130 survived and 66 died; 50 patients with hepatorenal syndrome were used for verification, of which 12 survived and 38 died. Inclusion criteria for hepatorenal syndrome: Diagnose and type HRS according to the definition and diagnostic criteria of HRS published by the International Ascites Research Group in 2007. 1) Liver cirrhosis with ascites; 2) Serum creatinine> 133 μmol / L; 3) Discontinue diuretics for at least 2 days and serum creatinine does not improve after albumin expansion (recommended albumin infusion dose is 1g / kg, the highest is up to 100g / d, blood creatinine improvement should be less than or e...

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Abstract

The invention discloses a system of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients. The system of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients includes an input device, a computing device and an output device, wherein the computing device includes a memory and a processor; a computer program is saved in the memory;the processor is configured to execute the computer program saved in the memory so as to realize the algorithm of a discrimination function; and the discrimination function returns the short-term prognosis of hepatorenal syndrome patients to be tested through liver cancer history, creatinine (Cr), neutrophilic granulocyte percentage (NE%) and glutamic-pyruvic transaminase (ALT). The system of determining short-term prognosis of hepatic cirrhosis and hepatorenal syndrome patients performs analysis and comparison by means of the current easily obtained clinic lab test index, establishes a survival prognosis scoring model for hepatic cirrhosis and hepatorenal syndrome patients, and guides the patients to further complete the related treatment to prolong the survival time of the patients.

Description

Technical field [0001] The present disclosure relates to the field of medicine, in particular, to a system for determining the short-term prognosis of patients with liver cirrhosis and hepatorenal syndrome. Background technique [0002] Liver cirrhosis hepatorenal syndrome (hepatorenal syndrome, HRS) is a functional renal failure that appears on the basis of severe liver disease. Its typical clinical manifestations are spontaneous oliguria or anuria, azotemia, dilutional hyponatremia and hyponatremia. Liver cirrhosis and hepatorenal syndrome are clinically divided into type I and type II. Type I HRS blood creatinine increases more than 2 times within 2 weeks, reaching or exceeding 226 μmol / L, and type II HRS blood creatinine increases between 133 and 226 μmol / L between. Type Ⅰ HRS is serious, with a rapid progress, with a median survival time of 2 weeks; Type Ⅱ HRS progresses relatively slowly, with relatively mild liver and kidney damage, with a median survival time of 6 month...

Claims

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Application Information

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IPC IPC(8): G16H50/20
CPCG16H50/20
Inventor 杨志云张栓刘晓利王宪波江宇泳杨玉英于浩
Owner BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIV
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