Flux-adjustable reaction device for peptide synthesis

A technology for peptide synthesis and reaction device, which is applied in the field of adjustable flux reaction devices, can solve the problems of inability to guarantee the quality of the synthesized polypeptides in the reaction efficiency, the inability to control the hand speed, and the large flow rate, so as to achieve a simple and clear design structure and avoid device instability. , to ensure the effect of reaction efficiency

Inactive Publication Date: 2018-11-09
南京肽业生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In order to solve the above problems, the present invention discloses a flux-adjustable reaction device for polypeptide synthesis. Unable to guarantee the reaction efficiency and the quality of synthetic peptides

Method used

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  • Flux-adjustable reaction device for peptide synthesis
  • Flux-adjustable reaction device for peptide synthesis

Examples

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Embodiment 1

[0019] Embodiment 1: see figure 1 and figure 2 Now, an adjustable flux reaction device for polypeptide synthesis provided by the present invention is described, which includes a kettle body 1 and a bracket 2 for supporting the kettle body 1, and the upper end of the kettle body 1 is provided with a feed port 3, The lower end of the kettle body 1 is provided with a discharge port 4, and the feed port 3 is connected with an external flux regulating unit 5, and the flux regulating unit 5 includes a feed pipe 6, and the other part of the feed pipe 6 is One end is connected to the funnel 7, and a pressure suspension ball 8 is arranged in the funnel 7, and the pressure suspension ball 8 is connected with the control module 10 on the upper end of the funnel 7 through an adjustment rod 9, and the adjustment rod 9 adopts a double-rod telescopic rod. A stirring unit 11 is provided in the kettle body 1, and the stirring unit 11 includes a plurality of stirring devices 12, and the stirr...

Embodiment 2

[0020] Example 2: see figure 2 , as an improvement of the present invention, the diameter of the mesh 16 is 1-3mm.

Embodiment 3

[0021] Embodiment 3: see figure 1 and figure 2 , as an improvement of the present invention, the stirring blade 15 is fixed on the rotating shaft 1301 by welding.

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Abstract

The invention discloses a flux-adjustable reaction device for peptide synthesis. The flux-adjustable reaction device comprises a kettle body, and a support used for supporting the kettle body, whereinthe upper end of the kettle body is provided with a feed inlet; the feed inlet is connected with an external flux adjusting unit; the external flux adjusting unit comprises a feeding pipe; the otherend of the feeding pipe is connected with a funnel; the interior of the funnel is provided with a pressure suspension ball which is connected with a control module located at the upper end of the funnel through an adjusting rod; the interior of the kettle body is provided with a stirring unit which comprises a stirrer; the stirrer comprises a rotating sleeve shaft which comprises a rotating shaftand a driving shaft; two ends of the driving shaft are connected with a driving unit; stirring blades are distributed on the outer periphery of the rotating shaft; each stirring blade is provided withmesh holes; and the lower end of the kettle body is externally connected with a vacuumizing unit. The flux-adjustable reaction device provided by the invention has the advantages of simple and cleardesign structure, closely-interconnected and non-interacting components, convenience in replacement of required parts, and easy repair and maintenance in the process of application in the future.

Description

technical field [0001] The invention relates to the field of chemical equipment, in particular to a flux-adjustable reaction device for polypeptide synthesis. Background technique [0002] In the 1990s, research in the field of peptides entered a new stage of development. Studies have shown that active peptides with a very small amount in organisms play an important role in regulating the life process. These active peptides are closely related to biological development, growth metabolism, immunity, disease, school, memory and aging, so scientists from various countries, including organic scientists, biologists, pharmacologists, structural chemists, etc., are closely related to life Science-related scientists are highly regarded. The synthesis of peptides needs to control the feeding speed. In the prior art, the feeding is mostly manual. During the feeding process, the hand speed cannot be controlled, resulting in too large or too small flow into the reaction device, which c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01J19/18B01J3/00B01J4/00B01J19/00B01J4/02
CPCB01J3/006B01J4/008B01J4/02B01J19/0053B01J19/0066B01J19/18B01J2204/002
Inventor 徐红岩马连芹徐大为杨明
Owner 南京肽业生物科技有限公司
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