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Kit for assessing function of cytotoxic immune cells in human peripheral blood and assessment method

A technology of immune cells and peripheral blood, applied in the medical field, can solve problems such as the lack of methods for comprehensively evaluating the immune function of human killer immune cells, and achieve the effects of improving health status, simple operation steps, and human safety

Inactive Publication Date: 2019-01-25
东莞暨南大学研究院
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Problems solved by technology

[0005] At present, neither clinical nor third-party testing institutions have a method that can comprehensively evaluate the immune function of human killer immune cells

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  • Kit for assessing function of cytotoxic immune cells in human peripheral blood and assessment method

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Embodiment Construction

[0029] As used herein:

[0030] "Prepared from" is synonymous with "comprising". As used herein, the terms "comprises," "including," "has," "containing," or any other variation thereof, are intended to cover a non-exclusive inclusion. For example, a composition, step, method, article, or device comprising listed elements is not necessarily limited to those elements, but may include other elements not explicitly listed or inherent to such composition, step, method, article, or device. elements.

[0031] The conjunction "consisting of" excludes any unspecified elements, steps or components. If used in a claim, this phrase will make the claim closed so that it does not contain material other than those described except for the customary impurities associated therewith. When the phrase "consisting of" appears in a clause of the subject of a claim rather than immediately following the subject matter, it only defines the elements described in that clause; other elements are not e...

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Abstract

The invention provides a kit for assessing a function of cytotoxic immune cells in human peripheral blood and an assessment method. The kit for assessing the function of cytotoxic immune cells in human peripheral blood provided by the invention comprises an anti-human CD3 antibody, an anti-human CD8 antibody, an anti-human CD45RA antibody, an anti-human CCR7 antibody, an anti-human CD28 antibody,an anti-human CD38 antibody, an anti-human CD57 antibody, an anti-human HLA-DR antibody, an anti-human PD-1 antibody, an anti-human CD56 antibody, an anti-human CD94 antibody, an anti-human NKP30 antibody, an anti-human NKP46 antibody, an anti-human NKG2D antibody, an anti-human KIR antibody, an anti-human Gamma Delta antibody and an anti-human V Delta 2 antibody, wherein all the antibodies are labeled by fluorescein. The kit for assessing the function of cytotoxic immune cells in human peripheral blood provided by the invention can be used for comprehensively assessing the immunity function of the cytotoxic immune cells in human peripheral blood, and is convenient and safe for use.

Description

technical field [0001] The invention relates to the medical field, in particular to a human peripheral blood killer immune cell function evaluation kit and evaluation method. Background technique [0002] Lymphocyte is a kind of white blood cell, which is the smallest white blood cell, produced by lymphoid organs, and is an important cell component of the body's immune response function. Lymphocytes are a type of cell line with immune recognition function. According to their migration, surface molecules and functions, they can be divided into T lymphocytes (also known as T cells), B lymphocytes (also known as B cells) and natural killer cells. (NK) cells. Both T cells and B cells are antigen-specific lymphocytes, and their initial source is the same, both from hematopoietic tissues. T lymphocytes circulate with the blood to the thymus and mature under the action of thymus hormones, etc., while B cells differentiate and mature in the bone marrow. [0003] When stimulated b...

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Application Information

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IPC IPC(8): G01N33/569
CPCG01N33/56972
Inventor 尹芝南吴扬哲
Owner 东莞暨南大学研究院
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