17 results about "NKG2D" patented technology

NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors. NKG2D is encoded by KLRK1 gene which is located in the NK-gene complex (NKC) situated on chromosome 6 in mice and chromosome 12 in humans. In mice, it is expressed by NK cells, NK1.1⁺ T cells, γδ T cells, activated CD8⁺ αβ T cells and activated macrophages. In humans, it is expressed by NK cells, γδ T cells and CD8⁺ αβ T cells. NKG2D recognizes induced-self proteins from MIC and RAET1/ULBP families which appear on the surface of stressed, malignant transformed, and infected cells.