A comprehensive quality evaluation method based on the detection of multiple active components of Scrophulariaceae

Abstract

The invention discloses a comprehensive quality evaluation method based on the detection of multiple active components of Scrophulariaceae, belonging to the technical field of traditional Chinese medicine quality detection. The method comprises the following steps: S1: content determination: through the content determination of harpagoside and harpagoside, to determine whether Scrophulariaceae meets the content requirements of "Chinese Pharmacopoeia"; S2: fingerprint similarity evaluation: using similarity analysis The characteristic map identification of aucubin, harpagoside, ferulic acid, angroside C, harpagoside, and cinnamic acid is used to increase the identification of the true and false quality of Scrophulariaceae, and the quality of Scrophulariaceae Evaluation of uniformity and stability; S3: Comprehensive scoring: Establish a weighted comprehensive evaluation system to comprehensively evaluate the quality of Scrophulariaceae. The invention increases the content measurement of cinnamic acid and the identification of the characteristic map of the main active components of Scrophulariae Scrophulariae, and conducts a comprehensive quality evaluation of the detected components through weighted scoring, which is beneficial to more accurately assessing the quality of Scrophulariaceae Scrophulariae.

Description

technical field [0001] The invention belongs to the technical field of quality detection of traditional Chinese medicines, and in particular relates to a comprehensive quality evaluation method based on the detection of multiple active components of Scrophulariaceae. Background technique [0002] Scrophulariaceae is the dry root of the Scrophulariaceae plant Scrophularianingpoensis Hemsl. Excavate when the stems and leaves wither in winter, remove rhizomes, young shoots, fibrous roots and sediment, sun or dry until half-dry, stack for 3 to 6 days, and repeat several times until dry. Scrophulariaceae is a commonly used Chinese medicinal material, which was first recorded in "Shen Nong's Materia Medica" and listed as a middle grade. "Bielu of Famous Doctors" says: "Where are the rivers and valleys and injustice sentences born?". Scrophulariaceae Alias: Yuanshen, Wuyuanshen, Black Ginseng, Chongtai, Guizang, Zhengma, Deer Intestine, Xuantai, Zhuma, Fucao, Wild Sesame, Angelic...

AI Technical Summary

Problems solved by technology

[0021] Due to the wide application of Scrophulariae Scrophulariae, many curative effects, and complex components, the current "Chinese Pharmacopoeia" only contains the TLC identification and content determination methods of harpagoside and harpagoside, while ignoring the detection and quality assessment of other active ingredients , cannot accurately evaluate the product quality and curative effect of Scrophulariaceae, and guide clinical medication

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