Rutaceae multi-species codon usage pattern analysis method and system

Abstract

The invention relates to a method for analyzing the codon usage pattern of multiple Rutaceae species, comprising: obtaining the codon sequence of each species through the genetic data of multiple Rutaceae species; extracting the first characteristic value of the codon sequence , verify the evolutionary relationship of the plurality of species with the relationship of the first eigenvalue; extract the second eigenvalue of the codon sequence, and draw a characteristic relationship diagram with the second eigenvalue to verify the evolutionary conservation of the plurality of species degree; extract the high-frequency codon / codon pair in the codon sequence, and verify the evolutionary conservation correlation of the multiple species with the relationship of the high-frequency codon / codon pair; the codon of the codon sequence The RSCU value was clustered with the codon RSCU value of the plant species, and the clustering results were used to verify the order of the multiple species; the Euclidean distance between the GC3 content of the codon sequence was obtained to verify the genetic relationship of the multiple species.

Description

Technical field [0001] The present invention belongs to the field of biological gene data analysis system, and specifically, a variety of species codon usage patterns and systems. Background technique [0002] As gene sequencing technology is increasing, more and more industries are analyzed, identified, predicting, etc. The codon is composed of three bases adjacent to mRNA, which determines the types and arrangements of the synthetic protein. Therefore, since Paul M.SHARP and Wen-HSiung Li are analyzed after the use of single-cell passwords, more and more animal and plants and microbial codons are exposed, and the importance of species is important and molecular evolutionary study. Waiting for basic theory data. However, most of the existing analytical model is for a single species analysis, and the analysis of the evolutionary direction is only a more macroscopic level, which is still in a blank for genetic evolution analysis of different species in the same belly. my country i...

AI Technical Summary

Problems solved by technology

[0008] To solve the problem of a single analysis method for codon data analysis in the prior art, the present invention proposes a multi-species codon usage pattern analysis method of Rutaceae, including: obtaining the genetic data of multiple species of Rutaceae, obtaining each The codon sequence of the species; extract the first characteristic value of the codon sequence, and verify the evolutionary relationship of the multiple species with the relationship of the first characteristic value; the first characteristic value includes the GC content of the codon sequence; extract The second eigenvalue of the codon sequence, using the second eigenvalue to draw a characteristic relationship diagram to verify the degree of evolutionary conservation of the multiple species; the second eigenvalue includes the GC12 average and GC3 average of the codon sequence Value, GC3s average value and ENC average value; extract the high-frequency codon / codon pair in the codon sequence, and verify the evolutionary conservation correlation of the multiple species with the relationship between the high-frequency codon / codon pair; The codon RSCU value of the codon sequence is clustered with the codon RSCU value of the plant species, and the classification of the multiple species is verified by the clustering result; the Euclidean distance between the GC3 content of the codon sequence is obtained to verify Genetic relationship of the multiple species

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