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Anti-Wrinkle Serum with Restructured Collagen

A technology for recombining collagen and essence, which is applied in the field of cosmetic preparations, can solve the problems of unsatisfactory anti-wrinkle effect and limit the wide application of collagen, and achieve good firming and anti-wrinkle, good transdermal and water-soluble effects

Active Publication Date: 2022-04-12
JIANGSU JLAND BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the origin of animals, there are still hidden dangers in biological safety, which greatly limits the wide application of collagen in various products such as cosmetics, food, and medicine, and its anti-wrinkle effect is still not ideal.

Method used

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  • Anti-Wrinkle Serum with Restructured Collagen
  • Anti-Wrinkle Serum with Restructured Collagen
  • Anti-Wrinkle Serum with Restructured Collagen

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The anti-wrinkle essence containing recombinant collagen contains the following ingredients by mass percentage: recombinant collagen 0.8%, glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5% %, Acetyl Hexapeptide-80.05%, Elastin 0.06%, Fibronectin 0.03%, and the balance is water. It is prepared by the following steps: add sodium hyaluronate, polyglutamic acid, recombinant collagen, elastin and fibronectin to glycerol in sequence according to the formula ratio, stir until the mixture is uniform, and then add 1,2-hexanediol, Add water to 100%, stir evenly until completely dissolved, and get the anti-wrinkle essence containing recombinant collagen.

[0022] In this example, the recombinant collagen is produced by fermentation of Pichia pastoris with a preservation number of CGMCC No. 5021, and other raw materials are conventional products sold in the market.

[0023] In this embodiment, the various raw materials mentioned above can be combin...

Embodiment 2

[0025] 1. Experimental products:

[0026] Cream: Water 68.65%, Carbomer 0.2%, Triethanolamine 0.2%, Xanthan Gum 0.1%, Glycerin 4%, Butylene Glycol 3%, Biosugar Gum-2 0.5%, Cetearyl Alcohol 1%, C20 -22 Alcohol Phosphate (and) C20-22 Alcohol 0.8%, Glyceryl Stearate 0.5%, Caprylic / Capric Glycerides 3%, Dimethicone 3%, Shea (BUTYROSPERMUM PARKII) Fruit 4.5% lipid, 0.15% methylparaben, 0.4% octanoyl hydroxamic acid, 0.5% 1,2-hexanediol.

[0027] The anti-wrinkle essence containing recombinant collagen contains the following ingredients by mass percentage: recombinant collagen 0.8%, glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5% %, Acetyl Hexapeptide-80.05%, Elastin 0.06%, Fibronectin 0.03%, and the balance is water.

[0028] Anti-wrinkle essence without recombinant collagen, including the following ingredients by mass percentage: glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5%, acetyl hexa Peptide-8 0.05%, el...

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PUM

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Abstract

The invention discloses a wrinkle-removing essence containing recombinant collagen, which belongs to the field of cosmetics. The anti-wrinkle essence includes the following components by mass percentage: 0.1%-1% of recombinant collagen, 10%-30% of glycerin, 1%-5% of 1,2-hexanediol, and 0.1% of sodium hyaluronate ~0.5%, polyglutamic acid 0.1%~0.5%, acetyl hexapeptide-8 0.05~2%, elastin 0.03~2%, fibronectin 0.01~1.5%, the balance is water. The present invention adopts the recombination of the recombinant collagen derived from microbial fermentation and other raw materials, so that problems such as precipitation, discoloration, and precipitation do not occur. The wrinkle-removing essence of the present invention is compounded with recombinant collagen, sodium hyaluronate, sodium polyglutamate, etc., and can better exert the tightening and wrinkle-removing effect of the recombinant collagen while moisturizing and locking water.

Description

technical field [0001] The invention belongs to the technical field of cosmetic preparations, and relates to a wrinkle-removing essence containing recombinant collagen. Background technique [0002] With the improvement of living standards, people have higher and higher requirements for the quality of life, and pay more attention to the appearance of the face. Wrinkles are the most visible and important feature of skin aging. People's wrinkles generally begin to appear around the age of 20, and gradually increase and deepen with age. With age, the epidermal tissue of the skin becomes dry and thin, collagen and elastin are gradually lost, and the fine mesh structure formed by the interweaving of collagen fibers and elastic fibers is destroyed, and wrinkles of different thicknesses will appear. People generally start to lose collagen at the age of 20, and enter the peak period of loss at the age of 25. At the age of 40, the content of collagen is less than half of that at th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/65A61K8/34A61K8/64A61K8/73A61K8/88A61Q19/00A61Q19/08
CPCA61K8/65A61K8/345A61K8/735A61K8/88A61K8/64A61Q19/08A61Q19/00A61K2800/85
Inventor 沈凤娟冯丽萍刘朱焰朱逸丽徐鹏程季乐赵健烽
Owner JIANGSU JLAND BIOTECH CO LTD
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