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Wrinkle-removing essence containing recombinant collagen

A technology for recombining collagen and essence, which is applied in the field of cosmetic preparations, can solve the problems of restricting the wide application of collagen and unsatisfactory anti-wrinkle effects, and achieve the effects of good skin penetration, easy absorption, and good water solubility

Active Publication Date: 2020-03-31
JIANGSU JLAND BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the origin of animals, there are still hidden dangers in biological safety, which greatly limits the wide application of collagen in various products such as cosmetics, food, and medicine, and its anti-wrinkle effect is still not ideal.

Method used

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  • Wrinkle-removing essence containing recombinant collagen
  • Wrinkle-removing essence containing recombinant collagen
  • Wrinkle-removing essence containing recombinant collagen

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The anti-wrinkle essence containing recombinant collagen contains the following ingredients by mass percentage: recombinant collagen 0.8%, glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5% %, Acetyl Hexapeptide-80.05%, Elastin 0.06%, Fibronectin 0.03%, and the balance is water. It is prepared by the following steps: add sodium hyaluronate, polyglutamic acid, recombinant collagen, elastin and fibronectin to glycerol in sequence according to the formula ratio, stir until the mixture is uniform, and then add 1,2-hexanediol, Add water to 100%, stir evenly until completely dissolved, and get the anti-wrinkle essence containing recombinant collagen.

[0022] In this example, the recombinant collagen is produced by fermentation of Pichia pastoris with a preservation number of CGMCC No. 5021, and other raw materials are conventional products sold in the market.

[0023] In this embodiment, the various raw materials mentioned above can be combin...

Embodiment 2

[0025] 1. Experimental products:

[0026] Cream: Water 68.65%, Carbomer 0.2%, Triethanolamine 0.2%, Xanthan Gum 0.1%, Glycerin 4%, Butylene Glycol 3%, Biosugar Gum-2 0.5%, Cetearyl Alcohol 1%, C20 -22 Alcohol Phosphate (and) C20-22 Alcohol 0.8%, Glyceryl Stearate 0.5%, Caprylic / Capric Glycerides 3%, Dimethicone 3%, Shea (BUTYROSPERMUM PARKII) Fruit 4.5% lipid, 0.15% methylparaben, 0.4% octanoyl hydroxamic acid, 0.5% 1,2-hexanediol.

[0027] The anti-wrinkle essence containing recombinant collagen contains the following ingredients by mass percentage: recombinant collagen 0.8%, glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5% %, Acetyl Hexapeptide-80.05%, Elastin 0.06%, Fibronectin 0.03%, and the balance is water.

[0028] Anti-wrinkle essence without recombinant collagen, including the following ingredients by mass percentage: glycerin 30%, 1,2-hexanediol 2.5%, sodium hyaluronate 0.5%, polyglutamic acid 0.5%, acetyl hexa Peptide-8 0.05%, el...

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Abstract

The invention discloses wrinkle-removing essence containing recombinant collagen, which belongs to the field of cosmetics. The wrinkle-removing essence is prepared from the following components in percentage by mass: 0.1%-1% of recombinant collagen, 10%-30% of glycerol, 1%-5% of 1, 2-hexanediol, 0.1%-0.5% of sodium hyaluronate, 0.1%-0.5% of polyglutamic acid, 0.05%-2% of acetyl hexapeptide-8, 0.03%-2% of elastin, 0.01%-1.5% of fibronectin and the balance of water. The recombinant collagen from microbial fermentation is compounded with other raw materials, so that the problems of precipitation,discoloration, precipitation and the like are avoided. According to the wrinkle-removing essence disclosed by the invention, the recombinant collagen, the sodium hyaluronate, the sodium polyglutamateand the like are compounded for use, so that the effects of tightening and removing wrinkles of the recombinant collagen can be better exerted while moisturizing and water locking are realized.

Description

technical field [0001] The invention belongs to the technical field of cosmetic preparations, and relates to a wrinkle-removing essence containing recombinant collagen. Background technique [0002] With the improvement of living standards, people have higher and higher requirements for the quality of life, and pay more attention to the appearance of the face. Wrinkles are the most visible and important feature of skin aging. People's wrinkles generally begin to appear around the age of 20, and gradually increase and deepen with age. With age, the epidermal tissue of the skin becomes dry and thin, collagen and elastin are gradually lost, and the fine mesh structure formed by the interweaving of collagen fibers and elastic fibers is destroyed, and wrinkles of different thicknesses will appear. People generally start to lose collagen at the age of 20, and enter the peak period of loss at the age of 25. At the age of 40, the content of collagen is less than half of that at th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/65A61K8/34A61K8/64A61K8/73A61K8/88A61Q19/00A61Q19/08
CPCA61K8/65A61K8/345A61K8/735A61K8/88A61K8/64A61Q19/08A61Q19/00A61K2800/85
Inventor 沈凤娟冯丽萍刘朱焰朱逸丽徐鹏程季乐赵健烽
Owner JIANGSU JLAND BIOTECH CO LTD
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