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Matching technology based on HE dyeing image and MBT dyeing image

An image and technology technology, applied in the field of matching based on HE-stained images and MBT-stained images, can solve the problems of high matching correct points, long time, and low matching correct points of K-nearest neighbor matching algorithm, so as to achieve accurate transformation matrix and enhanced matching. The effect of the probability of success

Pending Publication Date: 2021-06-04
上海镜观生物科技有限公司
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Problems solved by technology

[0006] In view of the deficiencies in the prior art, the present invention provides a matching technology based on HE stained images and MBT stained images, which solves the problem that the similar triangle matching algorithm proposed in the above background technology has a high number of correct points and a long time, while the K nearest neighbor matching algorithm matches the correct points lower and shorter issues

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  • Matching technology based on HE dyeing image and MBT dyeing image
  • Matching technology based on HE dyeing image and MBT dyeing image
  • Matching technology based on HE dyeing image and MBT dyeing image

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Embodiment Construction

[0031] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention.

[0032] see figure 1 The present invention provides a technical solution: a matching technique based on HE stained images and MBT stained images, comprising the following steps:

[0033] S1. Feature point extraction:

[0034] Use the orb algorithm to complete the extraction of HE stained images and MBT (IHC, IF and other special) stained image feature points;

[0035] S2, K nearest neighbor matching:

[0036] Based on the k-nearest neighbor matching algorithm, pre-screen M groups of matching feature points, k=2;

[0037] S3. Feature point pre-screening:

[0038] For the M pre-matched target feature points, select the two nearest different points from the original ...

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Abstract

The invention discloses a matching technology based on an HE dyeing image and an MBT dyeing image, and relates to the technical field of feature point matching of a special dyeing image to an HE dyeing image, and the method specifically comprises the steps: S1, feature point extraction; s2, K neighbor matching is carried out; s3, pre-screening feature points; s4, mismatching points are removed; and S5, extreme points are removed. According to the matching technology based on the HE dyeing image and the MBT dyeing image, a certain number of pre-matching point sets are screened out through a K close neighbor matching algorithm, on the basis of pre-matching, a similar triangle matching algorithm is used, mismatching points are further removed, through the combined matching algorithm, the matching success probability is increased, and the matching accuracy is improved. Registration failure caused by the fact that a wrong conversion matrix is obtained due to mismatching is reduced, interference of extreme points is further removed through K-Means, and the obtained conversion matrix is more accurate.

Description

technical field [0001] The invention relates to the technical field of feature point matching of special dyed images to HE dyed images, in particular to a matching technology based on HE dyed images and MBT dyed images. Background technique [0002] HE staining of pathological sections can observe cell and tissue morphology, and is the most basic and widely used technical method in histology, embryology, and pathology; while special staining such as IHC (immunohistochemistry), IF (immunofluorescence) and Masson Specific cells or specific components within cells can be labeled. The application of digital technology for whole slide scanning of pathological slides allows one pathological slide to be scanned multiple times to generate multiple digital images. By decolorizing the stained section and then performing other types of staining, digital images of two or more stainings of the same pathological paraffin section can be produced with the help of the digital technology of ...

Claims

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Application Information

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IPC IPC(8): G06K9/62
CPCG06F18/22G06F18/23213
Inventor 陈颖于观贞潘雅婷廖心怡周洲高云姝
Owner 上海镜观生物科技有限公司
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