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Microchip electrophoresis device

An electrophoresis device, microchip technology, applied in measuring devices, material analysis through electromagnetic means, instruments, etc., can solve problems such as incorrectly analyzing data and wasting time

Pending Publication Date: 2022-07-29
SHIMADZU SEISAKUSHO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, in many cases until now, the occurrence of such a malfunction was noticed after verifying the analysis data obtained by performing electrophoretic analysis on the sample, and there was a problem that incorrect analysis was obtained in this case. waste of time, samples

Method used

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Embodiment Construction

[0020] Hereinafter, an embodiment of the microchip electrophoresis apparatus according to the present invention will be described with reference to the accompanying drawings.

[0021] like figure 1 As shown, the microchip electrophoresis apparatus of this embodiment includes a plurality of microchips 2-1 to 2-4, a sample setting part 4, a separation buffer setting part 6, an introduction device 8, a voltage application device 10, a detection part 12, and a controller 14. Although not shown, the microchips 2-1 to 2-4 each have a flow path for electrophoresis inside, and the microchips 2-1 to 2-4 have ports on their upper surfaces that pass through both ends of the flow path, respectively. . In addition, in this embodiment, four microchips 2-1 to 2-4 are provided, but the present invention is not limited to this, and one or more microchips may be provided.

[0022] In the sample setting unit 4, one or more samples to be subjected to electrophoresis analysis and one or more st...

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Abstract

A microchip electrophoresis device is provided with: a sample setting unit for setting at least one sample and at least one standard sample; at least one microchip having a flow path for electrophoresis therein; an introduction device that introduces the separation buffer, the sample, and the standard sample into the flow path; a voltage applying device that applies a voltage to the flow path; a detection unit that acquires analysis data for electrophoretic analysis in the flow path; and a controller that controls the operation of the introduction device and the voltage application device, the controller being provided with: a standard data storage unit that stores standard data obtained by performing electrophoretic analysis on the standard sample under predetermined conditions; and a chip determination unit that performs chip determination before performing electrophoretic analysis on the sample by performing electrophoretic analysis on the standard sample using each microchip under predetermined conditions, acquiring analysis data of the standard sample by the detection unit, and comparing the acquired analysis data with standard data of the standard sample, it is determined whether or not the state of each microchip is suitable for electrophoretic analysis.

Description

technical field [0001] The invention relates to a microchip electrophoresis device. Background technique [0002] A microchip electrophoresis apparatus for performing electrophoretic analysis using a microchip is known (see Patent Document 1). The microchip electrophoresis apparatus can provide a plurality of microchips, and can perform electrophoretic analysis of many samples simultaneously and in parallel using the plurality of microchips. [0003] prior art literature [0004] Patent Literature [0005] Patent Document 1: Japanese Patent Laid-Open No. 2020-128904 SUMMARY OF THE INVENTION [0006] Invention to solve problem [0007] In the microchip electromigration apparatus, when performance of the microchip is degraded or the separation buffer filled in the microchip is wrong, accurate analysis data cannot be obtained even if the microchip is used for electrophoresis analysis. However, until now, in many cases, such inconveniences have not been noticed until the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/447
CPCG01N27/44791G01N27/44743G01N27/44782
Inventor 原田亨荻野康太熊谷英乡
Owner SHIMADZU SEISAKUSHO CO LTD
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