Adenosine receptor activation reagent and the uses of thereof

a technology of adenosine receptor and activation reagent, which is applied in the field of new adenosine a1 receptor agonist, can solve the problems of adenosine being hindered in the use of clinical drugs
US20160024135A1Inactive Publication Date: 2016-01-28ZHEJIANG SUB TROPICS CROP INST

Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
ZHEJIANG SUB TROPICS CROP INST
Publication Date
2016-01-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to application of N(6)-(2-hydroxyethyl)-adenosine (HEA) and its derivatives as an adenosine A1 receptor agonist in preparation of drug or food, the HEA and its derivatives are used in treatment of diseases relating to adenosine receptor regulator, such as insomnia, pain, convulsion, apoplexia, Parkinson's disease, opioid drug addiction and kidney ischemia reperfusion injury etc. The present invention provides a new method for treatment of the diseases relating to nervous system and kidney.
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Description

RELATED APPLICATIONS

[0001] The present application claims the priority from China Patent Application No. 201410360752.9 filed on Jul. 27, 2014, and China Patent Application No. 201510226745.4, filed on May 6, 2015. The entireties of these applications including all tables, diagrams and claims are incorporated hereby as reference of the present invention.TECHNICAL FIELD

[0002] The present invention relates to a new adenosine A1 receptor agonist, particularly, relates to N(6)-(2-hydroxyethyl)-adenosine (HEA) and its derivatives as adenosine A1 receptor agonist; and its new application as adenosine A1 receptor agonist in preparation of drug or food for prevention and treatment of the disease relating to adenosine receptor regulator.

[0003] Incorporated by reference herein in its entirety is the Sequence Listing entitled “sequence Listing.txt”, created Jul. 7, 2015, size of 2 kilobytes.BACKGROUND OF THE INVENTION

[0004] Cordyceps cicadae is a Cordyceps, in which the body is full of mycelium an...

Claims

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