Application of timosaponin for treating anxiety disorders

Abstract

An application of the timosaponin extracted from anemarrhena rhizome in preparing the medicine for treating dysphoria is disclosed. The preparing process of timosaponin is also disclosed.

Description

1. Technical field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to the application of timosaponin in treating anxiety. 2. Background technology

[0002] Anemarrhena is the rhizome of Liliaceae Anemarrhena, which grows on the sunny slopes of mountains and Lianggang areas. It is produced in Northeast China, Shanxi, Shaanxi, Henan, Hebei, Inner Mongolia and other places. Its nature and taste are bitter, sweet, and cold. Lung and kidney meridians, clearing away heat and restlessness, moistening dryness and nourishing yin. Traditional medicine believes that it is mainly used to treat strong heat and polydipsia, coma and delirium, lung heat cough, bone steaming night sweats and thirsty drinking. The active substance Zhimu extracted from Zhimu Saponins further enhance the traditional medicinal value of Anemarrhena. Anxiety disorder is the name of disease in Western medicine. The disease is a neurological disorder characterized by widespr...

Examples

Embodiment Construction

[0004] Choose the Anemarrhena plucked in spring or autumn, remove its fibrous roots, wash, dry, and slice, and then prepare the active substance of Anemarrhena by conventional methods, such as the ethanol infusion method, that is, timosaponin, the timosaponin For the preparation of medicines for treating anxiety disorders. And the test on the anxiolytic effect of yin-deficiency mice has fully proved the anxiolytic effect of timosaponin, which can be effectively used to prepare drugs for treating anxiety. The extraction method of anemarrhena extract timosaponin is: add 8 times the amount of 80% ethanol to the anemarrhena decoction pieces and reflux extraction three times, each time for 2 hours, filter through gauze, combine the filtrate, recover the ethanol from the filtrate until it has no alcohol smell, add appropriate amount of petroleum ether to degrease Extract three times, discard the petroleum ether layer, take the lower water layer, extract the water layer three times w...

1. Technical field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to the application of timosaponin in treating anxiety. 2. Background technology

[0002] Anemarrhena is the rhizome of Liliaceae Anemarrhena, which grows on the sunny slopes of mountains and Lianggang areas. It is produced in Northeast China, Shanxi, Shaanxi, Henan, Hebei, Inner Mongolia and other places. Its nature and taste are bitter, sweet, and cold. Lung and kidney meridians, clearing away heat and restlessness, moistening dryness and nourishing yin. Traditional medicine believes that it is mainly used to treat strong heat and polydipsia, coma and delirium, lung heat cough, bone steaming night sweats and thirsty drinking. The active substance Zhimu extracted from Zhimu Saponins further enhance the traditional medicinal value of Anemarrhena. Anxiety disorder is the name of disease in Western medicine. The disease is a neurological disorder characterized by widespr...

Examples

Embodiment Construction

[0004] Choose the Anemarrhena plucked in spring or autumn, remove its fibrous roots, wash, dry, and slice, and then prepare the active substance of Anemarrhena by conventional methods, such as the ethanol infusion method, that is, timosaponin, the timosaponin For the preparation of medicines for treating anxiety disorders. And the test on the anxiolytic effect of yin-deficiency mice has fully proved the anxiolytic effect of timosaponin, which can be effectively used to prepare drugs for treating anxiety. The extraction method of anemarrhena extract timosaponin is: add 8 times the amount of 80% ethanol to the anemarrhena decoction pieces and reflux extraction three times, each time for 2 hours, filter through gauze, combine the filtrate, recover the ethanol from the filtrate until it has no alcohol smell, add appropriate amount of petroleum ether to degrease Extract three times, discard the petroleum ether layer, take the lower water layer, extract the water layer three times w...