Prunus padus leaf volatile oil microcapsule preparation method and application

Abstract

The present invention relates to a prunus padus leaf volatile oil microcapsule preparation method and application. The wall materials of beta-cyclodextrin and gelatin are dissolved in hot water of 40-50 DEG C and stirred to dissolve, and the solution of wall material is obtained and reserved for the next steps; the prunus padus leaf volatile oil and the emulsified agent of monoglyceride are added to the solution, and homogenized to obtain an emulsion; and the obtained emulsion is put into an ultrasound device to conduct ultrasound, and is conducted refrigeration, suction filtration, and freeze-drying to obtain the prunus padus leaf volatile oil microcapsules. The prunus padus leaf volatile oil microcapsule has a simple preparation method, a good flowability and a high embedding rate, avoids the volatilization of the prunus padus leaf volatile oil microcapsule, can effectively extend storage time of the prunus padus leaf volatile oil; and also can prevent too high intake of cholesterol, and thereby reducing the incidences of vascular diseases.

Description

technical field

[0001] The invention relates to a preparation method and application of volatile oil microcapsules of thick plum leaves. Background technique

[0002] Thick plum is a plant of the genus Prunus in the Rosaceae, also known as stinky plum and stinky pear. The flowers, fruit, bark and leaves can be used as medicine, the leaves can relieve cough, the fruit can cure diarrhea, and the wood can be used for joinery. In the volatile oil of thick plum leaves, it contains relatively high phytol, that is, phytosterol, also known as phytol or flavonol, which is an unsaturated high-carbon alcohol, which is the synthesis of vitamin E and vitamin K. 1 raw materials. Phytol absorbed by the human body is not easy to accumulate in the body, easy to metabolize, and will not have adverse effects on human health. Because phytol has the effect of lowering cholesterol and can prevent animal cholesterol from being absorbed by the body, it has been called a blood vessel scavenger in...

Examples

Embodiment 1

[0029] 70g of wall material β -Dissolve cyclodextrin in 140mL of hot water at 40°C, stir to dissolve to obtain a wall material solution, and set aside; add 28g of thick plum leaf volatile oil and 2g of emulsifier monoglyceride to the above solution while stirring, Under the conditions of 70°C and pressure of 15MPa, homogenize twice for 5 minutes each time to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 200W, ultrasonic temperature 60°C, ultrasonic time 90min, and then The emulsion after ultrasound was refrigerated at 0°C for 48 hours, and the refrigerated liquid was filtered with medium-speed filter paper under the conditions of vacuum degree of 0.1MPa and temperature of 10°C, and the filter cake was placed in a freeze dryer with a vacuum degree of less than 20Pa and a cold trap temperature of -60°C. Drying under the sun, the thick plum leaf volatile oil microcapsules were obtained, and the embedding rate was 9...

Embodiment 2

[0031] 80g of wall material β -Dissolve cyclodextrin in 80mL of hot water at 50°C, stir and dissolve to obtain wall material solution, and set aside; while stirring, add 19g of thick plum leaf volatile oil and 1g of emulsifier monoglyceride into the above solution, Homogenize twice under the condition of 80°C and pressure of 20MPa, each time for 5min to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 100W, ultrasonic temperature 50°C, ultrasonic time 60min, and then The ultrasonic emulsion was refrigerated at 5°C for 48 hours, and the refrigerated liquid was filtered with a medium-speed filter paper at a vacuum of 0.08MPa and a temperature of 20°C, and the filter cake was placed in a freeze dryer with a vacuum of less than 20Pa and a cold trap temperature of -50°C Drying under the sun, the thick plum leaf volatile oil microcapsules were obtained, and the embedding rate was 94.4%.

Embodiment 3

[0033] 75g of wall material β - Dissolve cyclodextrin in 225mL of hot water at 45°C, stir to dissolve, and obtain a wall material solution for later use; while stirring, add 23.5g of volatile oil of thick plum leaves and 1.5g of emulsifier monoglyceride into the above solution, Homogenize twice under the conditions of temperature 75°C and pressure 18MPa, each time for 5 minutes, to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 150W, ultrasonic temperature 55°C, ultrasonic time 80min, Finally, the ultrasonic emulsion was refrigerated at 2°C for 48 hours, and the refrigerated liquid was filtered with a medium-speed filter paper at a vacuum of 0.09MPa and a temperature of 15°C. Drying under the condition of ℃, the volatile oil microcapsules of thick plum leaves were obtained, and the embedding rate was 89.8%.

technical field

[0001] The invention relates to a preparation method and application of volatile oil microcapsules of thick plum leaves. Background technique

[0002] Thick plum is a plant of the genus Prunus in the Rosaceae, also known as stinky plum and stinky pear. The flowers, fruit, bark and leaves can be used as medicine, the leaves can relieve cough, the fruit can cure diarrhea, and the wood can be used for joinery. In the volatile oil of thick plum leaves, it contains relatively high phytol, that is, phytosterol, also known as phytol or flavonol, which is an unsaturated high-carbon alcohol, which is the synthesis of vitamin E and vitamin K. 1 raw materials. Phytol absorbed by the human body is not easy to accumulate in the body, easy to metabolize, and will not have adverse effects on human health. Because phytol has the effect of lowering cholesterol and can prevent animal cholesterol from being absorbed by the body, it has been called a blood vessel scavenger in...

Examples

Embodiment 1

[0029] 70g of wall material β -Dissolve cyclodextrin in 140mL of hot water at 40°C, stir to dissolve to obtain a wall material solution, and set aside; add 28g of thick plum leaf volatile oil and 2g of emulsifier monoglyceride to the above solution while stirring, Under the conditions of 70°C and pressure of 15MPa, homogenize twice for 5 minutes each time to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 200W, ultrasonic temperature 60°C, ultrasonic time 90min, and then The emulsion after ultrasound was refrigerated at 0°C for 48 hours, and the refrigerated liquid was filtered with medium-speed filter paper under the conditions of vacuum degree of 0.1MPa and temperature of 10°C, and the filter cake was placed in a freeze dryer with a vacuum degree of less than 20Pa and a cold trap temperature of -60°C. Drying under the sun, the thick plum leaf volatile oil microcapsules were obtained, and the embedding rate was 9...

Embodiment 2

[0031] 80g of wall material β -Dissolve cyclodextrin in 80mL of hot water at 50°C, stir and dissolve to obtain wall material solution, and set aside; while stirring, add 19g of thick plum leaf volatile oil and 1g of emulsifier monoglyceride into the above solution, Homogenize twice under the condition of 80°C and pressure of 20MPa, each time for 5min to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 100W, ultrasonic temperature 50°C, ultrasonic time 60min, and then The ultrasonic emulsion was refrigerated at 5°C for 48 hours, and the refrigerated liquid was filtered with a medium-speed filter paper at a vacuum of 0.08MPa and a temperature of 20°C, and the filter cake was placed in a freeze dryer with a vacuum of less than 20Pa and a cold trap temperature of -50°C Drying under the sun, the thick plum leaf volatile oil microcapsules were obtained, and the embedding rate was 94.4%.

Embodiment 3

[0033] 75g of wall material β - Dissolve cyclodextrin in 225mL of hot water at 45°C, stir to dissolve, and obtain a wall material solution for later use; while stirring, add 23.5g of volatile oil of thick plum leaves and 1.5g of emulsifier monoglyceride into the above solution, Homogenize twice under the conditions of temperature 75°C and pressure 18MPa, each time for 5 minutes, to obtain an emulsion; put the obtained emulsion into an ultrasonic device, set the conditions as ultrasonic power 150W, ultrasonic temperature 55°C, ultrasonic time 80min, Finally, the ultrasonic emulsion was refrigerated at 2°C for 48 hours, and the refrigerated liquid was filtered with a medium-speed filter paper at a vacuum of 0.09MPa and a temperature of 15°C. Drying under the condition of ℃, the volatile oil microcapsules of thick plum leaves were obtained, and the embedding rate was 89.8%.

Images