Six-in-one anti-reversion particles and preparation method thereof

Abstract

The invention provides six-in-one anti-reversion particles and a preparation method thereof. The six-in-one anti-reversion particles are prepared from the following components in parts by weight: 600gof lily, 200 g of lindera aggregata, 200g of radix aucklandiae, 300g of vinegar-processed rhizoma corydalis, 300g of rhizoma cyperi, 180g of coptis chinensis, 60g of fructus evodiae and 240g of fructus aurantii. The invention also provides the preparation of the six-in-one anti-reversion particles. The preparation method comprises the following steps: S1) adding 5 times of water into the radix linderae, the radix aucklandiae, the rhizoma cyperi and the fructus aurantii, distilling for 3 hours, receiving distillate, standing, taking out a volatile oil layer for later use, and filtering a distilled water solution to obtain filtrate and medicine residues; S2) mixing the decoction dregs, lily, vinegar processed corydalis tuber, coptis chinensis and fructus evodiae, adding 8 times of water, decocting for three times, then filtering, combining filtrates, and standing overnight; and S3) taking out the supernatant of the combined filtrate. The six-in-one anti-reversion particles have a remarkable clinical effect on liver-stomach stagnated heat type esophagitis, have no recurrence and no side effect after drug withdrawal, and are convenient to popularize and use.

Description

technical field

[0001] The invention relates to the technical field of traditional Chinese medicine, in particular to Liuhezhifan granules and a preparation method thereof. Background technique

[0002] Reflux esophagitis is a common clinical manifestation of gastroesophageal reflux disease. It is a symptom or tissue damage caused by the reflux of gastric or duodenal contents into the esophagus. The main clinical manifestations are acid reflux, heartburn, and retrosternal pain. Severe cases have dysphagia. The main drugs for Western medicine treatment of reflux esophagitis are various proton pump inhibitors (PPIs). High, the patient's economic burden is heavy, and if it is used continuously for a long time, it will present potential risk factors that cannot be ignored. Studies have shown that: PPIs can affect the biological barrier of the intestinal tract by changing the normal intestinal flora, increasing the risk of enterogenous infection , PPI can hinder the absorption o...

Examples

Embodiment 1

[0019] Liuhezhifan granule, the composition and production amount of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, 240g of Citrus aurantium, Liuhe Zhifan granule made from the above eight kinds of traditional Chinese medicines does not have any additives, will not cause harm to the patient's body, and has a significant effect on patients with reflux esophagitis symptoms.

[0020] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0021] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and Medicinal dregs, aft...

Embodiment 2

[0026] Liuhezhifan granule, the composition and production quantity of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, and 240g of Citrus aurantii.

[0027] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0028] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and dregs;

[0029] S2): Mix medicinal dregs, lily, vinegar Corydalis, Coptis chinensis and Evodia rutaecarpa, add 8 times the amount of water, decoct three times, the first decoction time is 1.5 hours, the second and third decoction The cooking time ...

Embodiment 3

[0033] Liuhezhifan granule, the composition and production quantity of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, and 240g of Citrus aurantii.

[0034] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0035] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and dregs;

[0036] S2): Mix medicinal dregs, lily, vinegar Corydalis, Coptis chinensis and Evodia rutaecarpa, add 8 times the amount of water, decoct three times, the first decoction time is 1.5 hours, the second and third decoction The cooking time ...

technical field

[0001] The invention relates to the technical field of traditional Chinese medicine, in particular to Liuhezhifan granules and a preparation method thereof. Background technique

[0002] Reflux esophagitis is a common clinical manifestation of gastroesophageal reflux disease. It is a symptom or tissue damage caused by the reflux of gastric or duodenal contents into the esophagus. The main clinical manifestations are acid reflux, heartburn, and retrosternal pain. Severe cases have dysphagia. The main drugs for Western medicine treatment of reflux esophagitis are various proton pump inhibitors (PPIs). High, the patient's economic burden is heavy, and if it is used continuously for a long time, it will present potential risk factors that cannot be ignored. Studies have shown that: PPIs can affect the biological barrier of the intestinal tract by changing the normal intestinal flora, increasing the risk of enterogenous infection , PPI can hinder the absorption o...

Examples

Embodiment 1

[0019] Liuhezhifan granule, the composition and production amount of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, 240g of Citrus aurantium, Liuhe Zhifan granule made from the above eight kinds of traditional Chinese medicines does not have any additives, will not cause harm to the patient's body, and has a significant effect on patients with reflux esophagitis symptoms.

[0020] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0021] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and Medicinal dregs, aft...

Embodiment 2

[0026] Liuhezhifan granule, the composition and production quantity of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, and 240g of Citrus aurantii.

[0027] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0028] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and dregs;

[0029] S2): Mix medicinal dregs, lily, vinegar Corydalis, Coptis chinensis and Evodia rutaecarpa, add 8 times the amount of water, decoct three times, the first decoction time is 1.5 hours, the second and third decoction The cooking time ...

Embodiment 3

[0033] Liuhezhifan granule, the composition and production quantity of the Liuhezhifan granule are as follows: 600g of lily, 200g of black medicine, 200g of woody incense, 300g of vinegar made Corydalis cypress, 300g of Rhizoma Cyperi, 180g of Coptis chinensis, 60g of Evodia rutaecarpa, and 240g of Citrus aurantii.

[0034] The present invention also provides a preparation method of Liuhe Zhifan Granules, which includes the following steps:

[0035] S1): Add 5 times the amount of water to the black medicine, woody incense, Cyperus cyperi and Citrus aurantium, distill for 3 hours, receive the distillate, then stand still to take out the volatile oil layer for later use, filter the distilled aqueous solution to obtain the filtrate and dregs;

[0036] S2): Mix medicinal dregs, lily, vinegar Corydalis, Coptis chinensis and Evodia rutaecarpa, add 8 times the amount of water, decoct three times, the first decoction time is 1.5 hours, the second and third decoction The cooking time ...

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