A new type of self-cleaning and disinfecting tablet production equipment

By designing a new self-cleaning and disinfecting tablet production equipment, using the flow diversion device for hot air diversion and self-cleaning and disinfection, the problems of drug particles uniformity and powder leakage in drug tablet production are solved, and the drug production is realized Safety and uniformity of tablet forming.

CN115400023BActive Publication Date: 2025-02-07YANGZHOU ZHONGHUI PHARM CO LTD
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Patent Information

Application Number
CN202211001906.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-08-20
Publication Date
2025-02-07
Estimated Expiration
2042-08-20

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  • Figure CN115400023B_ABST
    Figure CN115400023B_ABST
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Abstract

The invention discloses a novel self-cleaning and disinfecting tabletting production equipment, comprising a supporting device, a shaping device, a flow guiding device and an ejection cylinder. The supporting device is connected to the shaping device, the shaping device and the flow guiding device are movably connected, the flow guiding device and the supporting device are connected by pipeline, the supporting device and the ejection cylinder are tightly connected, the ejection cylinder and the flow guiding device are transmission connected, the supporting device is the main supporting basis, and other devices are installed, the shaping device is used to shape the medicine tablets, the flow guiding device is used to guide the hot air, so that the tabletting space is self-cleaned and disinfected, the ejection cylinder is the tablet ejection power source, after the tabletting is completed, the molded tablet is ejected from the tabletting space by the ejection cylinder, so as to facilitate continuous tabletting, and the sterilization is carried out by the sterilization lamp in the sterilization chamber. The sterilized gas is guided into the molding chamber, so as to be sterilized in a sterile atmosphere, so as to ensure the safety of drug production.
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Description

Technical Field

[0001] The invention relates to the technical field of medicine tabletting production, in particular to a novel self-cleaning and disinfecting tabletting production equipment. Background Art

[0002] Tablets mainly refer to solid preparations that are formed into sheet-like shapes by evenly mixing drugs and related excipients and then forming them through pressure molding. Tablets are mainly for oral administration and also include some lozenges, chewable tablets and effervescent tablets.

[0003] In the conventional tablet production process, the wet particles are dried, and then the whole material is formed after drying. After mixing, the tablets are formed by pressure molding. Since the dried medicine is a drug particle, the uniformity of the drug particles cannot be guaranteed during the drying process. Therefore, when filling, the drug particles enter the tableting cavity, usually in a whole form, which will cause large fluctuations in the content of each component after the tableting of the medicine, affecting the uniformity of the tableting, especially for some drugs with strict requirements on the content of components. The fluctuation of the drug content may cause a certain degree of harm to the human body. In order to improve the accuracy of the tableting content, some powder medicine tableting processes are gradually formed, by further crushing the drug particles to form a powder, and directly tableting the powder medicine. However, after the medicine is formed into a powder, due to machine vibration and various air flow disturbances, it is easy to cause the powder to leak and fly, which not only causes waste, but also causes harm to the operator.

[0004] In addition, when tableting the medicine, due to unbalanced force, the medicine will adhere to the inner wall of the tableting cavity, which is easy to breed bacteria. After a long period of punching, it will also adhere to the punch, thus affecting the accuracy of the medicine tableting content. Summary of the invention

[0005] The object of the present invention is to provide a novel self-cleaning and sterilizing tabletting production equipment to solve the problems raised in the above-mentioned background technology.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions:

[0007] A new type of self-cleaning and disinfecting tablet production equipment comprises a supporting device, a shaping device, a flow guiding device and an ejection cylinder. The supporting device is connected to the shaping device, the shaping device and the flow guiding device are movably connected, the flow guiding device and the supporting device are connected by pipeline, the supporting device and the ejection cylinder are tightly connected, and the ejection cylinder and the flow guiding device are transmission connected.

[0008] The supporting device is the main supporting basis for installing other devices. The shaping device is used to shape the tablets, and the hot air is guided by the guide device, so as to self-clean and disinfect the tableting space. The ejection cylinder is the power source for tablet ejection. After the tableting is completed, the ejection cylinder ejects the formed tablets from the tableting space, which is convenient for continuous tableting.

[0009] Furthermore, the supporting device includes a shell, a lower pressure cylinder and a mounting seat, a power chamber is provided on the shell, the output end of the lower pressure cylinder passes through the power chamber, the cylinder body of the lower pressure cylinder and the shell are fastened, the output end of the lower pressure cylinder is transmission-connected with the mounting seat, the shaping device is placed at the lower end of the mounting seat, the shaping device includes an upper mold base, a lower mold plate and an adjusting component, a molding cavity is provided on the shell, the lower mold plate is placed in the molding cavity, a mold cavity is provided on the lower mold plate, the mounting seat is transmission-connected with the upper mold base through the adjusting component, the adjusting component includes a silo, a storage chamber is provided on the silo, an injection channel is provided on the upper mold base, the upper end of the injection channel is connected with a pipeline of the storage chamber, and the lower end of the injection channel faces the lower mold plate, The upper end of the upper die base is slidably connected to the storage chamber, a sterilization chamber is provided on the shell, the flow guide device includes a sterilization lamp, the sterilization lamp is placed in the sterilization chamber, there are at least two injection channels, and the injection channel outlets are arranged circumferentially along the lower side of the upper die base, the adjustment component also includes a booster pump, a sealing plate and a rotary motor, the sealing plate is placed in the storage chamber, the medicine is stored in the storage chamber under the sealing plate, the air outlet of the booster pump is connected to the storage chamber pipeline on the upper side of the sealing plate, a driving chamber is provided on the shell, the rotary motor is placed in the driving chamber, a gear is provided at the output end of the rotary motor, a toothed surface is provided on the upper die base, the gear and the toothed surface are meshed, and the rotary motor is intermittently connected to the upper die base through the gear;

[0010] During injection: the rotary motor is connected to the upper die seat through gears;

[0011] During tableting: the gears and toothed surfaces are connected by sliding.

[0012] The shell is installed on the lower template through the molding cavity, and the lower molding surface of the tablet is provided through the lower template. The output end of the lower pressure cylinder is guided by the power chamber. The lower pressure cylinder selects a hydraulic cylinder or a pneumatic cylinder according to the required pressure. The output displacement of the lower pressure cylinder drives the mounting seat to move downward, and the silo is fixed through the mounting seat. At the same time, the booster pump is installed. The sealing plate contacts the wall of the storage chamber. When injecting, the booster pump injects high-pressure gas to increase the pressure on the upper side of the sealing plate, so that the sealing plate moves downward, thereby extruding the material, and guiding the agent into the mold cavity through the injection channel. After the injection is completed , the lower pressure cylinder moves downward, driving the mounting seat, the silo and the upper die seat to move downward in turn for extrusion molding. The sterilization lamp in the sterilization chamber is used for high-temperature sterilization, and the sterilized gas is guided into the molding chamber, so as to sterilize in a sterile atmosphere to ensure the safety of drug production. At least two injection channels are set, and the outlet is located on the lower side of the upper die seat. Through the circumferential arrangement, the circumferential arrangement is carried out during injection, and the rotary motor is installed through the driving cavity. The rotary motor outputs torque and drives the upper die seat to rotate through the gear. The upper die seat performs circumferential distribution to improve the uniformity of distribution.

[0013] Furthermore, an internal thread is provided on the silo, and an external thread is provided on the upper mold base. The internal thread and the external thread are meshed, and the upper mold base and the silo thread are meshed. The shaping device also includes a sealing electric cylinder and a slider. A slide is provided on the inner side of the injection channel. The sealing electric cylinder is located at the upper end of the slide. The output end of the sealing electric cylinder is transmission-connected to the slider. The slider is in sliding contact with the slide. The bottom end of the slide is connected to the injection channel, and the diameter of the lower end of the slider is adapted to the outlet aperture of the injection channel.

[0014] Through the meshing of the internal thread and the external thread, the upper die seat is spirally ascended while distributing the material circumferentially. In the initial state, the injection channel of the upper die seat is located at the bottom position. As the injection progresses, the upper die seat rises steadily to ensure a constant injection spacing. The extruded agents at the lower ends of multiple injection channels are stacked in layers during the spiral ascent process, reducing the gap between layers. The spiral stacking is beneficial to the exhaust of the outer ring of the tablet. The outer ring of the tablet is a stress concentration surface with the greatest friction with the mold cavity, which prevents the pores generated by the injection from being located in the outer ring of the tablet, causing breakage when taking the tablet and affecting the tableting quality. The agent is injected in the form of fluid to perform precise injection and improve the tablet weight accuracy. The sealing electric cylinder is installed through the slide. When tableting, the output displacement of the sealing electric cylinder drives the slider to move along the slide to seal the injection channel outlet to ensure the flatness of the tableting surface.

[0015] Furthermore, the shaping device also includes a biasing assembly, a biasing groove is provided on the upper mold base, the biasing groove is connected to the injection channel, the biasing assembly includes a friction plate, a magnetic column and a coil, the friction plate is placed in the injection channel, one side of the friction plate is in contact with the wall of the injection channel, the magnetic column and the coil are respectively placed in the biasing groove, the coil is placed on the upper side of the magnetic column, the friction plate is connected to the magnetic column through a transmission rod, a pre-tightening spring is provided on the lower side of the magnetic column, and the magnetic column and the coil constitute a detection circuit.

[0016] The moisture content of the reagent is detected by the biasing component, and the magnetic column is located on the upper side of the biasing groove through the preload spring. The magnetic column is driven by the transmission rod to make the friction plate located at a higher position of the injection channel, so that the friction plate can slide unhindered within the sliding stroke of the transmission rod. The side of the friction plate close to the mold cavity is a smooth surface, and the other side is a friction surface. When the reagent enters the mold cavity under pressure, the friction plate is driven to slide down under the action of the friction force of the reagent. The higher the moisture content of the reagent, the smoother the surface, the smaller the friction between the reagent and the friction plate, and the lower the friction transmission ratio, thereby driving the friction plate to move down a smaller distance. The magnetic column is moved down through transmission, and the preload spring is compressed. During the downward movement of the magnetic column, the coil cuts the magnetic flux lines, and an induced current is generated in the detection circuit. The greater the downward movement distance of the magnetic column, the greater the current value, thereby performing real-time detection of the moisture content of the reagent.

[0017] Furthermore, an ejection groove is provided on the shell, and the ejection cylinder is placed in the ejection groove. The guide device also includes an air inlet pipe, an ejector rod and a bottom plate. The output end of the ejection cylinder is connected by transmission between the ejector rod and the bottom plate. The mold cavity is connected to the ejection groove, the bottom plate is placed at the bottom of the mold cavity, the air inlet pipe is connected to the sterilization chamber, and a heat exchange chamber is provided on the shell. The heat exchange chamber is connected to the lower end of the molding cavity, and the heat exchange chamber is located on the outside of the lower template.

[0018] The ejection cylinder is installed through the ejection groove, the output end of the ejection cylinder is connected to the bottom plate through the ejector rod, the air inlet pipe is connected to the high-pressure air source, and the compressed air flow is sent into the sterilization chamber for high-temperature sterilization. The hot air flow after high-temperature sterilization is sent into the heat exchange chamber. The lower template is a good conductor of heat, so the medicine in the lower template is exchanged with heat, the water in the medicine is evaporated, and a tablet is formed under pressure. After the tablet is formed, the output displacement of the ejection cylinder drives the ejector rod to move upward, thereby driving the bottom plate to move along the mold cavity, and the tablet is ejected from the mold cavity for automatic unloading.

[0019] Further, the sterilization lamp is electrically connected to the detection circuit.

[0020] After the moisture content of the agent is detected, the heating power of the sterilization lamp is controlled by the current value of the detection circuit. When the current value is less than the rated value, that is, the moisture content of the agent is too high, the sterilization lamp is controlled to increase the heating power to prevent the heating power from being too low to meet the drying requirements and cause storage deterioration, thereby improving the drying quality; when the current value is greater than the rated value, that is, the moisture content of the agent is too low, the sterilization lamp is controlled to reduce the heating power to prevent the heating power from being too high to increase energy consumption.

[0021] As an optimization, a reversing groove is provided on the shell, the arc of the reversing groove is gradually changed, and a slope is provided on the lower template;

[0022] During self-cleaning: the slope faces the reversing groove, and the tail end of the reversing groove faces the upper side of the bottom plate.

[0023] After the tablet is taken out, the ejector cylinder controls the bottom plate to move up so that the bottom plate is located at a certain height. The bottom side of the mold cavity is connected with the heat exchange chamber. The high-pressure hot air flow enters the mold cavity from the heat exchange chamber and moves up along the mold cavity, thereby automatically cleaning the mold cavity wall. The high-pressure hot air flow is guided by the slope surface and enters the reversing groove. Through the reversing groove with a gradual arc, the hot air flow is guided to the upper surface of the bottom plate, and the upper surface of the bottom plate is self-cleaned, thereby performing all-round cleaning.

[0024] As an optimization, the flow guide device also includes a reflux pipe, which is connected to the molding cavity. The high-pressure hot air flow is used to self-clean the pharmaceutical particles adhering to the mold cavity and the bottom plate, and the particles are recovered through the reflux pipe, thereby improving the recovery quality.

[0025] As an optimization, half of the length of the friction plate is longer than the sliding stroke of the transmission rod. By setting the length of the friction plate, the sliding stroke of the transmission rod is blocked, and the wedge-shaped setting of the upper end of the friction plate improves the fit between the friction plate and the mold cavity to prevent leakage.

[0026] Compared with the prior art, the beneficial effects achieved by the present invention are as follows: the present invention performs high-temperature sterilization through a sterilization lamp in the sterilization chamber, and the sterilized gas is guided into the molding chamber, thereby performing sterilization in a sterile atmosphere to ensure the safety of drug production; in the initial state, the injection channel of the upper mold seat is located at the bottom position, and the extruded medicines at the lower ends of multiple injection channels are stacked in layers during the spiral ascent process, which reduces the gap between layers. The spiral stacking is beneficial to the exhaust of the outer circle of the tablet, and the outer circle of the tablet is a stress concentration surface with the greatest friction with the mold cavity, which prevents the air holes generated by the injection from being located on the outer circle of the tablet, causing breakage when taking the tablet, affecting the tablet pressing quality, and injecting the medicine in the form of a fluid to perform precise injection and improve the tablet weight accuracy; when The agent enters the mold cavity under pressure, driving the friction plate to slide down, and through transmission, the magnetic column moves downward, the coil cuts the magnetic flux lines, and an induced current is generated in the detection circuit. The greater the downward distance of the magnetic column, the greater the current value, thereby performing real-time detection of the moisture content of the agent; after the moisture content of the agent is detected, the heating power of the sterilization lamp is controlled by the current value of the detection circuit. When the current value is less than the rated value, that is, the moisture content of the agent is too high, the sterilization lamp is controlled to increase the heating power to prevent the heating power from being too low to meet the drying requirements and cause storage deterioration, thereby improving the drying quality; when the current value is greater than the rated value, that is, the moisture content of the agent is too low, the sterilization lamp is controlled to reduce the heating power to prevent the heating power from being too high and increasing energy consumption. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0028] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0029] Figure 2 is a schematic diagram of the downward pressure power transmission of the present invention;

[0030] Figure 3 It is a schematic diagram of the structure of the shaping device of the present invention;

[0031] Figure 4 It is a schematic diagram of the injection guide of the present invention;

[0032] Figure 5 yes Figure 3 A magnified view of a part of the view;

[0033] Figure 6 It is a schematic diagram of the mold cavity self-cleaning structure of the present invention;

[0034] Figure 7 yes Figure 5 A magnified view of a part B of the view;

[0035] In the figure: 1-support device, 11-housing, 111-molding cavity, 112-power chamber, 113-driving cavity, 114-sterilization cavity, 115-heat exchange chamber, 116-reversing groove, 12-lower pressure cylinder, 13-mounting seat, 2-shaping device, 21-upper mold base, 211-injection channel, 212-slideway, 213-external thread, 214-toothed surface, 215-biased groove, 22-lower mold plate, 221-mold cavity, 222-slope surface, 23-adjustment group Parts, 231-silo, 2311-storage chamber, 2312-internal thread, 232-boost pump, 233-sealing plate, 234-rotating motor, 24-biasing assembly, 241-friction plate, 242-transmission rod, 243-magnetic column, 244-coil, 245-preload spring, 25-sealing electric cylinder, 26-slider, 3-flow guide device, 31-air inlet pipe, 32-sterilization lamp, 33-top rod, 34-bottom plate, 35-return pipe, 4-top cylinder. DETAILED DESCRIPTION

[0036] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] The present invention provides a technical solution:

[0038] like Figure 1 to Figure 7As shown, a new type of self-cleaning and disinfecting tablet production equipment includes a supporting device 1, a shaping device 2, a guide device 3 and an ejection cylinder 4, the supporting device 1 is connected to the shaping device 2, the shaping device 2 and the guide device 3 are movably connected, the guide device 3 and the supporting device 1 are connected by a pipeline, the supporting device 1 and the ejection cylinder 4 are fastened, and the ejection cylinder 4 and the guide device 3 are transmission connected.

[0039] The supporting device 1 is the main supporting basis for installing other devices. The shaping device 2 is used to shape the tablets, and the hot air is guided by the guide device 3, so that the tableting space is self-cleaned and disinfected. The ejection cylinder 4 is the power source for ejecting the tablets. After the tableting is completed, the ejection cylinder 4 is used to eject the formed tablets from the tableting space, so as to facilitate continuous tableting.

[0040] Furthermore, the supporting device 1 includes a shell 11, a lower pressure cylinder 12 and a mounting seat 13. The shell 11 is provided with a power chamber 112. The output end of the lower pressure cylinder 12 passes through the power chamber 112. The cylinder body of the lower pressure cylinder 12 is fastened to the shell 11. The output end of the lower pressure cylinder 12 is transmission-connected to the mounting seat 13. The shaping device 2 is placed at the lower end of the mounting seat 13. The shaping device 2 includes an upper mold base 21, a lower mold plate 22 and an adjusting component 23. The shell 11 is provided with a molding cavity 111. The lower mold plate 22 is placed in the molding cavity 111. The lower mold plate 22 is provided with a mold cavity 221. The mounting seat 13 is transmission-connected to the upper mold base 21 through the adjusting component 23. The adjusting component 23 includes a silo 231. The silo 231 is provided with a storage chamber 2311. The upper mold base 21 is provided with an injection channel 211. The upper end of the injection channel 211 is connected to the storage chamber 2311 through a pipeline. The lower end of the injection channel 211 faces the lower mold plate 22. The upper end of the seat 21 is slidably connected to the storage chamber 2311, the housing 11 is provided with a sterilization chamber 114, the flow guide device 3 includes a sterilization lamp 32, the sterilization lamp 32 is placed in the sterilization chamber 114, there are at least two injection channels 211, and the outlets of the injection channels 211 are arranged along the circumferential direction of the lower side of the upper mold seat 21, the adjustment component 23 also includes a booster pump 232, a sealing plate 233 and a rotary motor 234, the sealing plate 233 is placed in the storage chamber 2311, and the sealing plate 233 is placed in the storage chamber 2311. The medicine is stored in the storage chamber 2311 on the lower side, the air outlet of the booster pump 232 is connected to the storage chamber 2311 on the upper side of the sealing plate 233 through a pipeline, a driving chamber 113 is provided on the housing 11, a rotary motor 234 is placed in the driving chamber 113, a gear is provided at the output end of the rotary motor 234, a toothed surface 214 is provided on the upper die base 21, the gear and the toothed surface 214 are meshed, and the rotary motor 234 is intermittently connected to the upper die base 21 through the gear;

[0041] During injection: the rotary motor 234 is connected to the upper die base 21 through gears;

[0042] During tableting: the gear and the toothed surface 214 are connected in a sliding manner.

[0043] The shell 11 installs the lower template 22 through the molding cavity 111, provides the lower molding surface of the tablet through the lower template 22, guides the output end of the lower pressure cylinder 12 through the power chamber 112, and the lower pressure cylinder 12 selects a hydraulic cylinder or a pneumatic cylinder according to the required pressure. The output displacement of the lower pressure cylinder 12 drives the mounting seat 13 to move downward, fixes the material bin 231 through the mounting seat 13, and installs the booster pump 232 at the same time. The sealing plate 233 contacts the wall of the storage chamber 2311. When injecting, the booster pump 232 injects high-pressure gas to increase the pressure on the upper side of the sealing plate 233, so that the sealing plate 233 moves downward, thereby extruding the material, and guiding the medicine into the mold cavity 221 through the injection channel 211 After the injection is completed, the output end of the lower pressure cylinder 12 moves downward, driving the mounting seat 13, the material bin 231 and the upper mold seat 21 to move downward in turn for extrusion molding. The sterilization lamp 32 in the sterilization chamber 114 is used for high-temperature sterilization, and the sterilized gas is guided into the molding chamber 111, so as to sterilize in a sterile atmosphere to ensure the safety of drug production. At least two injection channels 211 are set, and the outlet is located at the lower side of the upper mold seat 21. Through the circumferential arrangement, the circumferential arrangement is carried out during the injection, and the rotary motor 234 is installed through the driving chamber 113. The rotary motor 234 outputs torque and drives the upper mold seat 21 to rotate through the gear. The upper mold seat 21 performs circumferential distribution to improve the uniformity of distribution.

[0044] Furthermore, an internal thread 2312 is provided on the silo 231, and an external thread 213 is provided on the upper mold base 21. The internal thread 2312 and the external thread 213 are meshed, and the upper mold base 21 and the silo 231 are threadedly meshed. The shaping device 2 also includes a sealing cylinder 25 and a slider 26. A slide 212 is provided on the inner side of the injection channel 211. The sealing cylinder 25 is located at the upper end of the slide 212. The output end of the sealing cylinder 25 is transmission-connected with the slider 26. The slider 26 is in sliding contact with the slide 212. The bottom end of the slide 212 is connected to the injection channel 211. The diameter of the lower end of the slider 26 is adapted to the outlet aperture of the injection channel 211.

[0045] The internal thread 2312 and the external thread 213 are meshed, so that the upper die seat 21 is spirally ascended while distributing the material circumferentially. In the initial state, the injection channel 211 of the upper die seat 21 is located at the bottom position. As the injection progresses, the upper die seat 21 rises steadily to ensure that the injection spacing is constant. The extruded medicines at the lower ends of the multiple injection channels 211 are stacked in layers during the spiral ascent process, reducing the gap between the layers. The spiral stacking is beneficial to the exhaust of the outer ring of the tablet. The outer ring of the tablet is a stress concentration surface, and the friction with the mold cavity 221 is the greatest, which prevents the pores generated by the injection from being located in the outer ring of the tablet, causing fragmentation when taking the tablet, affecting the tableting quality. The material is injected in the form of a fluid agent, and precise injection is performed to improve the tablet weight accuracy. The sealing electric cylinder 25 is installed through the slide 212. When tableting, the output displacement of the sealing electric cylinder 25 drives the slider 26 to move along the slide 212 to seal the outlet of the injection channel 211 to ensure the flatness of the tableting surface.

[0046] Furthermore, the shaping device 2 also includes a biasing assembly 24, a biasing groove 215 is provided on the upper mold base 21, the biasing groove 215 is connected to the injection channel 211, the biasing assembly 24 includes a friction plate 241, a magnetic column 243 and a coil 244, the friction plate 241 is placed in the injection channel 211, one side of the friction plate 241 is in contact with the wall of the injection channel 211, the magnetic column 243 and the coil 244 are respectively placed in the biasing groove 215, the coil 244 is placed on the upper side of the magnetic column 243, the friction plate 241 is connected to the magnetic column 243 through a transmission rod 242, a pre-tightening spring 245 is provided on the lower side of the magnetic column 243, and the magnetic column 243 and the coil 244 constitute a detection circuit.

[0047] The moisture content of the medicine is detected by the biasing component 24, and the magnetic column 243 is located on the upper side of the biasing groove 215 by the preload spring 245. The magnetic column 243 is driven by the transmission rod 242, so that the friction plate 241 is located at a higher position of the injection channel 211, so that the friction plate 241 can slide unhindered within the sliding stroke of the transmission rod 242. The friction plate 241 is smooth on one side close to the mold cavity 221, and is frictionally frictional on the other side. When the medicine enters the mold cavity 221 under pressure, under the action of the friction force of the medicine, The friction plate 241 is driven to slide down. The higher the moisture content of the medicine, the smoother the surface, the smaller the friction between the friction plate 241 and the friction transmission ratio, thereby driving the friction plate 241 to move down a smaller distance. Through transmission, the magnetic column 243 is moved down and the preload spring 245 is compressed. During the downward movement of the magnetic column 243, the coil 244 cuts the magnetic flux lines and generates an induced current in the detection circuit. The greater the downward movement distance of the magnetic column 243, the greater the current value, thereby performing real-time detection of the moisture content of the medicine.

[0048] Furthermore, an ejection groove is provided on the shell 11, and the ejection cylinder 4 is placed in the ejection groove. The guide device 3 also includes an air inlet pipe 31, a push rod 33 and a bottom plate 34. The output end of the ejection cylinder 4 is transmission-connected with the bottom plate 34 through the push rod 33. The mold cavity 221 is connected with the ejection groove. The bottom plate 34 is placed at the bottom end of the mold cavity 221. The air inlet pipe 31 is connected with the sterilization chamber 114. A heat exchange chamber 115 is provided on the shell 11. The heat exchange chamber 115 is connected with the lower end of the molding cavity 111, and the heat exchange chamber 115 is located on the outside of the lower template 22.

[0049] The ejection cylinder 4 is installed through the ejection groove, and the output end of the ejection cylinder 4 is connected to the bottom plate 34 through the ejector rod 33. The air inlet pipe 31 is connected to the high-pressure air source, and the compressed air flow is sent into the sterilization chamber 114 for high-temperature sterilization. The hot air flow after high-temperature sterilization is sent into the heat exchange chamber 115. The lower template 22 is a good conductor of heat, so that the medicine in the lower template 22 is heat exchanged, the water in the medicine is evaporated, and a tablet is formed under pressure. After the tablet is formed, the output displacement of the ejection cylinder 4 drives the ejector rod 33 to move upward, thereby driving the bottom plate 34 to move along the mold cavity 221, and the tablet is ejected from the mold cavity 221 for automatic unloading.

[0050] Furthermore, the sterilization lamp 32 is electrically connected to the detection circuit.

[0051] After the moisture content of the medicine is detected, the heating power of the sterilization lamp 32 is controlled by the current value of the detection circuit. When the current value is less than the rated value, that is, the moisture content of the medicine is too high, the sterilization lamp 32 is controlled to increase the heating power to prevent the heating power from being too low to meet the drying requirements and cause storage deterioration, thereby improving the drying quality; when the current value is greater than the rated value, that is, the moisture content of the medicine is too low, the sterilization lamp 32 is controlled to reduce the heating power to prevent the heating power from being too high to increase energy consumption.

[0052] As an optimization, a reversing groove 116 is provided on the housing 11, and the reversing groove 116 is gradually arranged in arc, and a slope 222 is provided on the lower template 22;

[0053] During self-cleaning: the slope 222 faces the reversing groove 116 , and the tail end of the reversing groove 116 faces the upper side of the bottom plate 34 .

[0054] After the pressed tablets are taken out, the ejection cylinder 4 controls the bottom plate 34 to move upward so that the bottom plate 34 is located at a certain layer height, the bottom side of the mold cavity 221 is connected with the heat exchange chamber 115, and the high-pressure hot air flow enters the mold cavity 221 from the heat exchange chamber 115 and moves upward along the mold cavity 221, thereby automatically cleaning the wall surface of the mold cavity 221, and guiding it through the slope surface 222, the high-pressure hot air flow enters the reversing groove 116, and through the reversing groove 116 with a gradually changing arc, the hot air flow is guided to the upper surface of the bottom plate 34, and the upper surface of the bottom plate 34 is self-cleaned, thereby performing all-round cleaning.

[0055] As an optimization, the flow guide device 3 further includes a reflux pipe 35, which is connected to the molding cavity 111. The high-pressure hot air flow is used to self-clean the pharmaceutical particles adhering to the mold cavity 221 and the bottom plate 34, and the particles are recovered through the reflux pipe 35, thereby improving the recovery quality.

[0056] As an optimization, half the length of the friction plate 241 is longer than the sliding stroke of the transmission rod 242. The sliding stroke of the transmission rod 242 is blocked by setting the length of the friction plate 241, and the wedge-shaped setting of the upper end of the friction plate 241 improves the fit between the friction plate 241 and the mold cavity 221 to prevent material leakage.

[0057] The working principle of the present invention is as follows: high-temperature sterilization is performed by the sterilization lamp 32 in the sterilization chamber 114, and the sterilized gas is guided into the molding chamber 111, so as to perform sterilization in a sterile atmosphere to ensure the safety of drug production; in the initial state, the injection channel 211 of the upper mold base 21 is located at the bottom position, and as the injection proceeds, the upper mold base 21 rises steadily to ensure a constant injection spacing, and the extruded medicines at the lower ends of the multiple injection channels 211 are stacked in layers during the spiral ascent process, reducing the gap between layers, and the spiral stacking is conducive to the exhaust of the outer circle of the tablet, which is a stress concentration surface and has the greatest friction with the mold cavity 221, preventing the pores generated by the injection from being located on the outer circle of the tablet, causing fragmentation when the tablet is taken out, and injecting the medicine in the form of a fluid to perform precise injection and improve the tablet weight accuracy; when the medicine enters the mold cavity 221 under pressure, it is driven by the friction of the medicine The friction plate 241 slides down, and the higher the moisture content of the agent, the smoother the surface, the smaller the friction between the friction plate 241, and the lower the friction transmission ratio, thereby driving the friction plate 241 to move down a smaller distance. Through transmission, the magnetic column 243 moves down and compresses the preload spring 245. During the downward movement of the magnetic column 243, the coil 244 moves to cut the magnetic flux lines, and an induced current is generated in the detection circuit. The greater the downward movement distance of the magnetic column 243, the greater the current value. After the moisture content of the agent is detected, the heating power of the sterilization lamp 32 is controlled by the current value of the detection circuit. When the current value is less than the rated value, that is, when the moisture content of the agent is too high, the sterilization lamp 32 is controlled to increase the heating power to prevent the heating power from being too low and unable to meet the drying requirements. When the current value is greater than the rated value, that is, when the moisture content of the agent is too low, the sterilization lamp 32 is controlled to reduce the heating power to prevent the heating power from being too high and increasing energy consumption.

[0058] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0059] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A new type of self-cleaning and disinfecting tablet production equipment, characterized in that: The novel tableting production equipment comprises a supporting device (1), a shaping device (2), a flow guiding device (3) and an ejecting cylinder (4); the supporting device (1) is connected to the shaping device (2); the shaping device (2) and the flow guiding device (3) are movably connected; the flow guiding device (3) and the supporting device (1) are connected by a pipeline; the supporting device (1) and the ejecting cylinder (4) are tightly connected; and the ejecting cylinder (4) and the flow guiding device (3) are drivingly connected; The supporting device (1) comprises a shell (11), a pressing cylinder (12) and a mounting seat (13); a power chamber (112) is provided on the shell (11); an output end of the pressing cylinder (12) passes through the power chamber (112); a cylinder body of the pressing cylinder (12) and the shell (11) are tightly connected; the output end of the pressing cylinder (12) and the mounting seat (13) are transmission-connected; the shaping device (2) is placed at the lower end of the mounting seat (13); the shaping device (2) comprises an upper die seat (21), a lower die plate (22) and an adjusting component (23); a shaping device (2) is provided on the shell (11); The molding cavity (111) is provided with a lower mold plate (22) disposed in the molding cavity (111), a mold cavity (221) is provided on the lower mold plate (22), the mounting seat (13) is transmission-connected to the upper mold seat (21) via an adjusting component (23), the adjusting component (23) comprises a silo (231), a storage chamber (2311) is provided on the silo (231), an injection channel (211) is provided on the upper mold seat (21), an upper end of the injection channel (211) is connected to the storage chamber (2311) via a pipeline, and a lower end of the injection channel (211) faces the lower mold plate (22), and the The upper end of the upper mold base (21) is slidably connected to the storage chamber (2311); the housing (11) is provided with a sterilization chamber (114); the flow guide device (3) comprises a sterilization lamp (32); the sterilization lamp (32) is placed in the sterilization chamber (114); there are at least two injection channels (211); the outlets of the injection channels (211) are arranged along the circumference of the lower side of the upper mold base (21); the adjustment component (23) further comprises a booster pump (232), a sealing plate (233) and a rotary motor (234); the sealing plate (233) is placed in the storage chamber (2311); the sealing plate The medicine is stored in the storage chamber (2311) on the lower side of the mold (233), the air outlet of the booster pump (232) is connected to the storage chamber (2311) on the upper side of the sealing plate (233) by a pipeline, the housing (11) is provided with a driving chamber (113), the rotary motor (234) is placed in the driving chamber (113), the output end of the rotary motor (234) is provided with a gear, the upper mold base (21) is provided with a toothed surface (214), the gear and the toothed surface (214) are meshed, and the rotary motor (234) is intermittently connected to the upper mold base (21) through the gear; During injection: the rotary motor (234) is connected to the upper die base (21) through a gear; During tableting: the gear and the toothed surface (214) are slidably connected; The silo (231) is provided with an internal thread (2312), the upper die seat (21) is provided with an external thread (213), the internal thread (2312) and the external thread (213) are meshed, the upper die seat (21) and the silo (231) are threadedly meshed, the shaping device (2) further comprises a sealing electric cylinder (25) and a slider (26), the inner side of the injection channel (211) is provided with a slideway (212), the sealing electric cylinder (25) is located at the upper end of the slideway (212), the output end of the sealing electric cylinder (25) and the slider (26) are transmission-connected, the slider (26) and the slideway (212) are in sliding contact, the bottom end of the slideway (212) is connected to the injection channel (211), and the diameter of the lower end of the slider (26) is adapted to the outlet aperture of the injection channel (211).

2. A new type of self-cleaning and disinfecting tablet production equipment according to claim 1, characterized in that: The shaping device (2) further comprises a biasing assembly (24); a biasing groove (215) is provided on the upper die seat (21); the biasing groove (215) is communicated with the injection channel (211); the biasing assembly (24) comprises a friction plate (241), a magnetic column (243) and a coil (244); the friction plate (241) is arranged in the injection channel (211); one side of the friction plate (241) is in contact with the wall surface of the injection channel (211); the magnetic column (243) and the coil (244) are respectively arranged in the biasing groove (215); the coil (244) is arranged on the upper side of the magnetic column (243); the friction plate (241) is transmission-connected to the magnetic column (243) via a transmission rod (242); a preload spring (245) is arranged on the lower side of the magnetic column (243); and the magnetic column (243) and the coil (244) form a detection circuit.

3. A new type of self-cleaning and disinfecting tablet production equipment according to claim 2, characterized in that: The shell (11) is provided with an ejection groove, the ejection cylinder (4) is placed in the ejection groove, the flow guide device (3) also includes an air inlet pipe (31), an ejector rod (33) and a bottom plate (34), the output end of the ejection cylinder (4) is transmission-connected via the ejector rod (33) and the bottom plate (34), the mold cavity (221) is connected to the ejection groove, the bottom plate (34) is placed at the bottom end of the mold cavity (221), the air inlet pipe (31) is connected to the sterilization cavity (114), and the shell (11) is provided with a heat exchange chamber (115), the heat exchange chamber (115) is connected to the lower end of the molding cavity (111), and the heat exchange chamber (115) is located outside the lower mold plate (22).

4. A new type of self-cleaning and disinfecting tablet production equipment according to claim 3, characterized in that: The sterilization lamp (32) is electrically connected to the detection circuit.

5. A new type of self-cleaning and disinfecting tablet production equipment according to claim 4, characterized in that: The shell (11) is provided with a reversing groove (116), the reversing groove (116) is arranged with a gradually changing arc, and the lower template (22) is provided with a slope surface (222); During self-cleaning: the slope (222) faces the reversing groove (116), and the tail end of the reversing groove (116) faces the upper side of the bottom plate (34).

6. A novel self-cleaning and disinfecting tablet production equipment according to claim 5, characterized in that: The flow guiding device (3) further comprises a return pipe (35), wherein the return pipe (35) is in communication with the molding cavity (111).

7. A new type of self-cleaning and disinfecting tablet production equipment according to claim 6, characterized in that: Half the length of the friction plate (241) is longer than the sliding stroke of the transmission rod (242).

Citation Information

Patent Citations

  • Automatic tabletting forming machine for tablets

    CN112060666A

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    CN114223769A