Blood plasma separating clamp

Abstract

The utility model discloses a blood plasma separating clamp, and relates to the technical field of biological experiment equipment. The movable clamping plate and the fixed clamping plate are arranged on the base and used for fixing a blood bag, a fixing plate is further fixed to the base, and the fixed clamping plate and the fixing plate are movably connected and swing on the fixing plate along a preset path. As the fixed clamping plate moves, the contact area between the fixed clamping plate and the blood sampling bag can be changed. When hematopoietic stem cells at the two corners of a blood collection bag are collected, the stem cells at the corners of the blood collection bag can be collected even if the whole plasma separation clamp is not shaken. Meanwhile, due to the fact that the plasma separating clamp is not shaken, it can be guaranteed that blood in the blood collecting bag basically maintains the layering effect after centrifugation for layered collection, the recovery rate of hematopoietic stem cells can be increased, and the removal rate of red blood cells can be increased.

Description

Technical Field

[0001] The utility model relates to the technical field of biological experimental equipment, in particular to a blood plasma separation clamp. Background Art

[0002] With the rapid development of biotechnology, stem cells, as the origin cells of the body with the functions of replication and multidirectional differentiation, play a huge role in human development, aging and disease treatment, and have attracted widespread attention from countries around the world. How to effectively separate and preserve stem cells from blood components has become one of the research hotspots in today's scientific field.

[0003] The common method at present is to use a centrifuge to separate the blood components into layers, and then use a separator clamp to separate the effective components. The existing blood separation clamp usually includes a fixed splint and a movable splint. The position between the movable splint and the fixed splint is changed, and the blood collection bag is placed between the two splints and fixed; under the squeezing of the separator clamp, the red blood cell layer in the blood collection bag rises, pushing the white blood cell layer and plasma layer up; through the pigtail of the blood collection bag, the white blood cell layer, plasma layer and part of the red blood cells are collected with a transfer bag to complete the layered collection of plasma; the collected hematopoietic stem cells are mixed with an appropriate volume of cryopreservation solution and transferred to the cryopreservation bag for deep low temperature storage.

[0004] The positional relationship between the movable splint and the fixed splint can adopt a reciprocating movement type, such as the structure recorded in the patent with patent application number CN201520219367.2 and the name of a blood plasma clamp; the connection structure between the movable splint and the fixed splint can also adopt a rotating structure, such as the structure recorded in the patent with patent application number CN202120767356.3 and the name of a blood plasma clamp.

[0005] In both of the above patents, the blood collection bag is fixed by two splints with variable positions. In actual use, in order to collect as much white blood cell layer as possible, after the blood collection bag is fixed on the plasma separation clamp, it is necessary to swing the plasma separation clamp left and right to allow the white blood cell layer in the upper left and upper right corners of the blood collection bag to flow into the transfer bag through the pigtail; and in this process, if the shaking force is too strong, there is a risk of remixing of the white blood cell layer and the red blood cell layer in the blood collection bag, resulting in the problem of low blood stem cell recovery rate of the existing plasma separation clamp. Utility Model Content

[0006] In view of the deficiencies in the prior art, the utility model provides a blood plasma separator, which can effectively reduce or avoid the problem of remixing of the white blood cell layer and the red blood cell layer in the blood collection bag caused by excessive external force of shaking the plasma separator, thereby ensuring that the plasma separator has a higher recovery rate of hematopoietic stem cells.

[0007] To achieve the above-mentioned purpose, the utility model adopts the following technical solution: a blood plasma separation clamp, including a base and a movable clamp and a fixed clamp arranged on the base for fixing the blood bag, a fixed plate is also fixed on the base, the fixed clamp and the fixed plate are movably connected and swing on the fixed plate along a preset path.

[0008] Compared with the prior art, the utility model has the following beneficial effects:

[0009] The movable clamping plate and the fixed clamping plate can clamp the blood collection bag by parallel movement in the prior art, or by rotating the movable clamping plate to clamp the blood collection bag, ensuring that the fixed clamping plate and the movable clamping plate cooperate to clamp the blood collection bag.

[0010] After the movable splint and the fixed splint fix the blood collection bag, since the fixed splint and the fixed plate are movably connected, the fixed splint can be swung along a preset path on the fixed plate under the action of external force. As the fixed splint moves, the contact area between the fixed splint and the blood collection bag can be changed. When collecting hematopoietic stem cells at the two corners of the blood collection bag, even if the entire separation clamp is not shaken, the stem cells at the corners of the blood collection bag can be collected. At the same time, since the separation clamp is not shaken, it can also ensure that the blood in the blood collection bag basically maintains the stratification effect after centrifugation for stratified collection, which is beneficial to improve the recovery rate of hematopoietic stem cells and the removal rate of red blood cells.

[0011] Furthermore, the movable clamping plate is arranged on one side of the fixed clamping plate, and the fixed plate is arranged on the other side of the fixed clamping plate and is arranged in close contact with the fixed clamping plate;

[0012] A connecting shaft pin is fixed on the fixed clamping plate, and the connecting shaft pin is rotatably connected to the fixed plate. A limiting sliding member is provided between the fixed clamping plate and the fixed plate. The limiting sliding member includes a circular arc-shaped slide groove and a slider embedded in the slide groove, wherein the arc center of the slide groove and the axis of the connecting shaft pin are collinearly arranged.

[0013] Furthermore, a rotatably connected ball is embedded in the slide block, and the ball is in rolling contact with the bottom of the slide groove.

[0014] Furthermore, a connecting shaft pin is fixed on the other side of the fixed clamping plate and is perpendicular to the fixed clamping plate. The connecting shaft pin passes through the fixed plate and is connected to an action block.

[0015] Furthermore, the connecting shaft pin is fixed on the other side of the fixed clamping plate and is perpendicular to the fixed clamping plate. The connecting shaft pin passes through the fixed plate and is rotatably connected to the fixed plate. The connecting shaft pin is driven or braked by the first driving assembly.

[0016] The first driving assembly comprises a first pulley coaxially fixed with the connecting shaft pin, a second pulley connected with the first pulley through a transmission belt, and a servo motor coaxially arranged with the second pulley, and the servo motor is fixed to the base.

[0017] Furthermore, the connecting shaft pin is fixed on the other side of the fixed clamping plate and is perpendicular to the fixed clamping plate. The connecting shaft pin passes through the fixed plate and is rotatably connected to the fixed plate. The connecting shaft pin is driven or braked by the second driving assembly.

[0018] The second driving assembly includes a large turntable coaxially fixed with the connecting shaft pin, a driving motor fixed with the base and a small turntable coaxially arranged with the driving motor. The eccentric position of the large turntable and the eccentric position of the small turntable are connected by a movable rod, and the movable rod and the large turntable and the small turntable are all hinged.

[0019] Furthermore, a flow rate controller is also fixed on the fixed plate.

[0020] Furthermore, the lower part of the movable clamping plate is hinged to the base and is squeezed toward the fixed clamping plate under the action of the elastic member. An action rod is fixed on the movable clamping plate, and the action rod cooperates with a hook fixed on the base to limit the movable clamping plate.

[0021] Furthermore, it also includes a horizontal correction component, which includes four supporting legs arranged to be lifted and lowered at the bottom of the base and a horizontal bubble meter fixed on the base.

[0022] Furthermore, each support leg includes a threaded rod and a support pad arranged up and down, and the threaded rod is vertically arranged and threadedly connected to a threaded hole opened at the bottom of the base. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a structural appearance diagram of one embodiment of the utility model;

[0024] Figure 2 It is a cross-sectional view of one embodiment of the present utility model;

[0025] Figure 3 for Figure 2 A schematic diagram of the structure of another state in FIG.

[0026] Figure 4 It is a front view of the fixing plate of the utility model;

[0027] Figure 5 It is a rear view of the fixing plate of the utility model;

[0028] Figure 6 for Figure 2 Enlarged view of part A in the middle;

[0029] Figure 7 A cross-sectional view of a first drive assembly provided in the utility model;

[0030] Figure 8 A cross-sectional view of a second drive assembly provided in the utility model;

[0031] Fig. 9 for Figure 8The main view of the connection between the medium and large turntables, the small turntable and the movable rod;

[0032] Fig.10 It is a structural schematic diagram of one of the connection modes of the movable clamping plate and the fixed clamping plate of the utility model;

[0033] Fig.11 It is a structural schematic diagram of another connection method between the movable clamping plate and the fixed clamping plate of the utility model;

[0034] Fig.12 This is a schematic diagram of the structure of the horizontal correction component of the utility model.

[0035] In the figure: base 1, hook 11, rotating groove 12, action rod 13, threaded hole 14, horizontal bubble meter 15, positioning shaft 16, support pad 17, threaded rod 18, sliding groove 19, screw rod 110, spring 111, moving rod 112, movable splint 2, movable sleeve 21, T-bar 201, fixed splint 3, connecting shaft pin 31, slider 32, ball 321, fixed plate 4, action block 41, slide groove 42, rotating hole 43, flow rate controller 5, first pulley 61, transmission belt 62, second pulley 63, servo motor 64, large turntable 71, movable rod 72, small turntable 73, drive motor 74. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0037] like Figure 1-8 As shown, a blood plasma clamp comprises a base 1 and a movable clamp 2 and a fixed clamp 3 for fixing a blood bag arranged on the base 1. A fixed plate 4 is also fixed on the base 1. The fixed clamp 3 and the fixed plate 4 are movably connected and swing on the fixed plate 4 along a preset path.

[0038] In the present practicality, the base 1 is used to provide support force and also facilitate the installation of various components. In this embodiment, the base 1 adopts a horizontally arranged plate-like structure, the fixed plate 4 is vertically fixed above the base 1, the fixed plate 4 and the fixed clamping plate 3 are arranged in close contact, and the movable clamping plate 2 is arranged on the side of the fixed clamping plate 3 away from the fixed plate 4. The fixed clamping plate 3 and the movable clamping plate 2 are used to fix the blood collection bag. For this purpose, the clamping method of the fixed clamping plate 3 and the movable clamping plate 2 on the blood collection bag can be a parallel movement clamping in the prior art, or it can be a method of rotating the movable clamping plate 2 to clamp the blood collection bag, ensuring that the fixed clamping plate 3 and the movable clamping plate 2 can cooperate to achieve the clamping of the blood collection bag.

[0039] like Fig.10As shown, in one embodiment of the utility model, the movable clamping plate 2 and the fixed clamping plate 3 clamp the blood collection bag in a relative moving manner. Specifically, the fixed clamping plate 3 is arranged in contact with the fixed plate 4, and a T-shaped rod 201 is fixed to the bottom of the movable clamping plate 2. The vertical section of the T-shaped rod 201 is embedded in the sliding groove 19 provided on the base 1. A screw rod 110 is provided in the sliding groove 19 for rotation. The T-shaped rod 201 is sleeved on the screw rod 110 and is threadedly connected to the screw rod 110. The end of the screw rod 110 passes through the base 1 and is rotatably connected to the base 1 through a bearing. When in use, an external force drives the screw rod 110 to rotate, driving the T-shaped rod 201 and the movable clamping plate 2 to move toward the fixed clamping plate 3, so that the blood collection bag can be fixed between the fixed clamping plate 3 and the movable clamping plate 2. Of course, as the blood in the blood collection bag decreases, the screw rod 110 needs to be rotated appropriately to ensure that the movable clamping plate 2 and the fixed clamping plate 3 can fix blood collection bags of different volumes.

[0040] like Fig.11 As shown, in another embodiment of the utility model, the movable clamping plate 2 and the fixed clamping plate 3 clamp the blood collection bag in a relative moving manner. Specifically, the fixed clamping plate 3 is arranged in contact with the fixed plate 4, a T-shaped rod 201 is fixed to the bottom of the movable clamping plate 2, and the vertical section of the T-shaped rod 201 is embedded in the sliding groove 19 provided on the base 1, and a moving rod 112 is fixed to the lower end of the T-shaped rod 201, and the moving rod 112 is arranged through the base 1, and a spring 111 is sleeved on the moving rod 112, and the spring 111 is arranged between the base 1 and the T-shaped rod 201. Then, the external force pulling the moving rod 112 can drive the distance between the movable clamping plate 2 and the fixed clamping plate 3 to change, and is used to place the blood collection bag. After the blood collection bag is in place, the external force applied to the moving rod 112 is slowly withdrawn, which can drive the movable clamping plate 2 to move and fix the blood collection bag between the movable clamping plate 2 and the fixed clamping plate 3.

[0041] like Figure 2 , 3As shown, in another embodiment of the utility model, in this embodiment, the blood collection bag is fixed between the movable clamping plate 2 and the fixed clamping plate 3 by rotating the movable clamping plate 2. Specifically, the lower part of the movable clamping plate 2 is hinged with the base 1 and is pressed toward the fixed clamping plate 3 under the action of the elastic member. An action rod 13 is fixed on the movable clamping plate 2, and the action rod 13 cooperates with the hook 11 fixed on the base 1 to limit the movable clamping plate 2. A movable sleeve 21 is arranged below the movable clamping plate 2, and a rotating groove 12 is provided on the base 1. A positioning shaft 16 is fixed in the rotating groove 12. The movable sleeve 21 is sleeved on the positioning shaft 16, and a torsion spring (not shown in the figure) is arranged between the positioning shaft 16 and the movable sleeve 21. The torsion spring is an elastic member. When in use, external force acts on the action rod 13, driving the movable clamping plate 2 to rotate. The action rod 13 is clamped on the hook 11, which can keep the movable clamping plate 2 at a certain angle. At this time, the blood collection bag is placed between the fixed clamping plate 3 and the movable clamping plate 2. The external force slowly disappears, and the movable clamping plate 2 rotates in the opposite direction under the action of the torsion spring and squeezes the fixed clamping plate 3 to fix the blood collection bag between the fixed clamping plate 3 and the movable clamping plate 2. The rotation angle of the movable clamping plate 2 can be limited by the structure of the rotation groove 12 and the movable sleeve 21.

[0042] Of course, considering that the volume of blood in the blood collection bag will become smaller and smaller during the layered collection process, as shown in the figure, the method of using elastic parts to provide squeezing force can avoid manual pushing, which is more convenient in actual operation.

[0043] After ensuring that the moving clamp 2 and the fixed clamp 3 fix the blood collection bag, it is necessary to collect the plasma in the blood collection bag in layers. In this process, the blood at the corners of the blood collection bag is not easy to collect. In order to avoid the problem of remixing of the white blood cell layer and the red blood cell layer after stratification in the blood collection bag caused by shaking the entire separation clamp in the prior art, the utility model is further provided with a fixed plate 4 on the basis of the original fixed clamp 3 and the moving clamp 2. The fixed plate 4 is fixed to the base 1, the fixed clamp 3 is movably connected to the fixed plate 4, and the fixed clamp 3 can swing on the fixed plate 4 along a preset path under the action of an external force. When collecting the hematopoietic stem cells at the two corners of the blood collection bag, even if the entire separation clamp is not shaken, the stem cells at the corners of the blood collection bag can be collected. At the same time, since the separation clamp is not shaken, it can also ensure that the blood in the blood collection bag basically maintains the stratification effect after centrifugation for stratification collection, which is conducive to improving the recovery rate of hematopoietic stem cells and the removal rate of red blood cells.

[0044] like Figure 2-6As shown, in this embodiment, the connection mode of the fixed clamping plate 3 and the fixed plate 4 is limited, ensuring that the fixed clamping plate 3 is movably connected to the fixed plate 4 and can also swing on the fixed plate 4 according to a preset trajectory under the action of an external force. Specifically, a connecting shaft pin 31 is fixed to the fixed clamping plate 3, and the connecting shaft pin 31 is rotatably connected to the fixed plate 4. A limiting sliding member is provided between the fixed clamping plate 3 and the fixed plate 4, and the limiting sliding member includes a circular arc-shaped slide groove 42 used in conjunction with each other and a slider 32 embedded in the slide groove 42, wherein the arc center of the slide groove 42 and the axis of the connecting shaft pin 31 are arranged in a colinear manner. The connecting shaft pin 31 and the fixed plate 4 are rotatably connected to realize the movable connection between the fixed clamping plate 3 and the fixed plate 4. The setting of the limiting sliding member can limit the moving path of the fixed clamping plate 3 on the fixed plate 4 through the shape of the slide groove 42 or the extended arc angle. The slide groove 42 can be set on the fixed plate 4 or on the fixed clamping plate 3. The purpose of swing limit can be achieved by ensuring that the slider 32 and the slide groove 42 are respectively set on the fixed clamping plate 3 and the fixed plate 4. In the utility model, the slide groove 42 is opened on the side of the fixed plate 4 close to the fixed clamping plate 3, and the slider 32 is convexly set on the side of the fixed clamping plate 3 close to the fixed plate 4. The slide groove 42 can be a dovetail groove, a square groove, a wedge groove, etc. The slider 32 is a structure matching the slide groove 42 to ensure that the slider 32 can slide along the slide groove 42. Through the limit of the slide groove 42 and the slider 32, the swing distance and swing angle of the fixed clamping plate 3 on the fixed plate 4 can be limited.

[0045] like Figure 2 , 6 As shown, in order to reduce the friction force of the slider 32 sliding in the slide groove 42, in this embodiment, a rotatably connected ball 321 is embedded in the slider 32, and the ball 321 rolls in contact with the bottom of the slide groove 42. The ball 321 can reduce the friction force of the slider 32 moving along the slide groove 42, so that the fixed clamping plate 3 moves more smoothly.

[0046] Of course, in order to prevent the changed fixed clamping plate 3 from easily moving to the original position after the external force disappears, the slide groove 42 and the slider 32 can adopt a damped sliding method; or, the rotation connection between the connecting shaft pin 31 and the fixed plate 4 is connected by a damped rotation method.

[0047] The position limitation of the fixed clamping plate 3 after rotation can be achieved by damping rotation, such as Figure 2 , 3As shown, in this embodiment, the connecting shaft pin 31 is fixedly connected to the fixed clamping plate 3. Then, under the action of external force, the fixed clamping plate 3 is changed to be fixed on the other side of the fixed clamping plate 3 and perpendicular to the fixed clamping plate 3. The connecting shaft pin 31 passes through the rotation hole 43 opened on the fixed plate 4 and is connected with the action block 41. The cooperation of the action block 41 and the connecting shaft pin 31 is equivalent to the role of the positioning anchor bolt. The existence of the action block 41 creates a certain squeezing force between the fixed clamping plate 3 and the fixed plate 4, so that the connecting shaft pin 31 and the fixed plate 4 are connected in a damping rotation manner. After the external force acts on the fixed clamping plate 3 to change the position of the fixed clamping plate 3 on the fixed plate 4, the fixed clamping plate 3 has a certain ability to resist position recovery, ensuring that the fixed clamping plate 3 with a changed position can maintain its position unchanged within a certain period of time, ensuring that the blood at the corners of the blood collection bag is collected smoothly.

[0048] Of course, the rotation and limit of the connecting shaft pin 31 can also be achieved by mechanical driving and braking, for example: Figure 7 As shown, in another embodiment of the utility model, the connecting shaft pin 31 is fixed on the other side of the fixed clamping plate 3 and is perpendicular to the fixed clamping plate 3, the connecting shaft pin 31 passes through the fixed plate 4 and is rotatably connected to the fixed plate 4, and the connecting shaft pin 31 is driven or braked by a first driving assembly, and the first driving assembly includes a first pulley 61 coaxially fixed with the connecting shaft pin 31, a second pulley 63 connected to the first pulley 61 through a transmission belt 62, and a servo motor 64 coaxially arranged with the second pulley 63, and the servo motor 64 is fixed to the base 1. The rotation direction and rotation angle of the servo motor 64 are controlled by a PWM signal, and the second pulley 63 and the first pulley 61 are driven to rotate a certain angle in a specific direction, and the connecting shaft pin 31 and the fixed clamping plate 3 are driven to rotate a specific angle. At this time, the servo motor 64 is braked, and it is ensured that the fixed clamping plate 3 maintains this position. Of course, the first pulley 61 and the second pulley 63 can be sprockets, and the transmission belt 62 can be a roller chain. This method can better achieve the braking between the wheel and the chain.

[0049] like Figure 8 , 9As shown, in another embodiment of the utility model, a mechanical driving and braking mechanism is also provided. Specifically, the connecting shaft pin 31 is fixed on the other side of the fixed clamping plate 3 and is perpendicular to the fixed clamping plate 3. The connecting shaft pin 31 passes through the fixed plate 4 and is rotatably connected to the fixed plate 4. The connecting shaft pin 31 is driven or braked by a second driving assembly. The second driving assembly includes a large turntable 71 coaxially fixed with the connecting shaft pin 31, a driving motor 74 fixed with the base 1, and a small turntable 73 coaxially arranged with the driving motor 74. The eccentric position of the large turntable 71 and the eccentric position of the small turntable 73 are connected by a movable rod 72. The movable rod 72 and the large turntable 71 and the small turntable 73 are all hinged. The driving motor 74 adopts a servo motor or a stepping motor. Then, by using the diameter ratio of the large turntable 71 and the small turntable, the small turntable 73 can be rotated one circle, and the large turntable rotates within a certain angle range. Correspondingly, the driving motor 74 drives the small turntable 73 to rotate, and the rotation of the small turntable 73 drives the large turntable 71 to rotate, thereby driving the connecting shaft pin 31 and the fixed clamping plate 3 to rotate, and the driving motor 74 brakes to achieve braking of the fixed clamping plate 3.

[0050] During the blood collection process, the blood collection bag needs to be clamped with a hemostatic forceps, and the operator controls the force of the hemostatic forceps to adjust the bleeding speed. While ensuring that the bleeding speed is slow and gentle, the operator also needs to observe the electronic balance and swing the plasma separation clamp. It is easy for the operator to lose concentration, resulting in the bleeding speed being fast and slow, affecting the final recovery rate of red blood cells and hematopoietic stem cells. To solve this problem, Figure 2 , 3 As shown in Figures 7 and 8, in another embodiment of the utility model, a flow rate controller 5 is also fixed on the fixed plate 4. The flow rate controller 5 adopts an infusion tube flow rate controller 5. Before collecting blood components, the blood collection bag pigtail is passed through the flow rate controller 5, and then the roller on the flow rate controller 5 is rolled to change the squeezing force on the pigtail, thereby changing the flow rate of the fluid in the pigtail, which can ensure that the flow rate is relatively consistent during the blood stratification collection process and ensure a better recovery rate of red blood cells and hematopoietic stem cells.

[0051] The base 1 is arranged horizontally so that the fixed plate 4, the movable clamping plate 2 and the fixed clamping plate 3 can collect the blood in layers in an optimal matching relationship. Fig.12 As shown, in another embodiment of the utility model, a horizontal correction component is also included, and the horizontal correction component includes four rectangular legs arranged at the bottom of the base 1 and a horizontal bubble meter 15 fixed on the base 1. Each leg includes a threaded rod 18 and a support pad 17 arranged up and down, and the threaded rod 18 is vertically arranged and threadedly connected to the threaded hole 14 opened at the bottom of the base 1. When in use, the base 1 is placed on the operating table, and the position of the bubble in the horizontal bubble meter 15 is observed to adjust the appropriate leg height so that the bubble in the horizontal bubble meter 15 is centered, and the position of the base 1 is adjusted to ensure the use effect of the entire pulp separation clamp.

[0052] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A blood separation clamp, comprising a base (1) and a movable clamp (2) and a fixed clamp (3) provided on the base (1) for fixing a blood bag, characterized in that: A fixing plate (4) is also fixed on the base (1), and the fixed clamping plate (3) and the fixing plate (4) are movably connected and swing on the fixing plate (4) along a preset path.

2. A blood plasma separation clamp according to claim 1, characterized in that: The movable clamping plate (2) is arranged on one side of the fixed clamping plate (3), and the fixed plate (4) is arranged on the other side of the fixed clamping plate (3) and is arranged in close contact with the fixed clamping plate (3); A connecting shaft pin (31) is fixed on the fixed clamping plate (3), and the connecting shaft pin (31) is rotatably connected to the fixed plate (4). A limiting sliding member is provided between the fixed clamping plate (3) and the fixed plate (4), and the limiting sliding member includes a circular arc-shaped slide groove (42) and a slider (32) embedded in the slide groove (42), wherein the arc center of the slide groove (42) and the axis of the connecting shaft pin (31) are arranged colinearly.

3. A blood plasma separation clamp according to claim 2, characterized in that: A rotatably connected ball bearing (321) is embedded in the slider (32), and the ball bearing (321) is in rolling contact with the bottom of the slide groove (42).

4. A blood plasma separation clamp according to claim 3, characterized in that: The connecting shaft pin (31) is fixed on the other side of the fixed clamping plate (3) and is perpendicular to the fixed clamping plate (3). The connecting shaft pin (31) passes through the fixed plate (4) and is connected to an action block (41).

5. The blood plasma separation clamp according to claim 3, characterized in that: The connecting shaft pin (31) is fixed on the other side of the fixed clamping plate (3) and is perpendicular to the fixed clamping plate (3). The connecting shaft pin (31) passes through the fixed plate (4) and is rotatably connected to the fixed plate (4). The connecting shaft pin (31) is driven or braked by the first driving component. The first driving assembly comprises a first pulley (61) coaxially fixed with the connecting shaft pin (31), a second pulley (63) connected to the first pulley (61) via a transmission belt (62), and a servo motor (64) coaxially arranged with the second pulley (63), wherein the servo motor (64) is fixed to the base (1).

6. The blood plasma separation clamp according to claim 3, characterized in that: The connecting shaft pin (31) is fixed on the other side of the fixed clamping plate (3) and is perpendicular to the fixed clamping plate (3). The connecting shaft pin (31) passes through the fixed plate (4) and is rotatably connected to the fixed plate (4). The connecting shaft pin (31) is driven or braked by the second driving component. The second driving assembly comprises a large rotating disk (71) fixed coaxially with the connecting shaft pin (31), a driving motor (74) fixed with the base (1), and a small rotating disk (73) arranged coaxially with the driving motor (74); the eccentric position of the large rotating disk (71) and the eccentric position of the small rotating disk (73) are connected via a movable rod (72); the movable rod (72) and the large rotating disk (71) and the small rotating disk (73) are all hinged.

7. A blood plasma separation clamp according to any one of claims 1 to 6, characterized in that: A flow rate controller (5) is also fixed on the fixed plate (4).

8. The blood plasma separation clamp according to claim 7, characterized in that: The lower part of the movable clamping plate (2) is hinged to the base (1) and is pressed toward the fixed clamping plate (3) under the action of an elastic member. An action rod (13) is fixed on the movable clamping plate (2). The action rod (13) and a hook (11) fixed on the base (1) cooperate to limit the movable clamping plate (2).

9. A blood plasma separation clamp according to claim 1, 2, 3, 4, 5, 6 or 8, characterized in that: It also includes a horizontal correction component, which includes four supporting legs arranged to be lifted at the bottom of the base (1) and a horizontal bubble meter (15) fixed on the base (1).

10. The blood plasma separation clamp according to claim 9, characterized in that: Each support leg comprises a threaded rod (18) and a support pad (17) arranged vertically, and the threaded rod (18) is arranged vertically and is threadedly connected to a threaded hole (14) provided at the bottom of the base (1).

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