Biomarker detection kit

Abstract

The utility model discloses a biomarker detection kit which comprises a kit body and a kit cover hinged with the kit body through a hinge, a pipettor groove used for placing a pipettor and a gun head, a comparison paper groove used for placing comparison card paper, a beaker groove used for placing a beaker and a test tube groove used for placing different test tubes are respectively arranged on the working surface of the kit body, an inner cavity is formed in the box body, a rotating mechanism is mounted at an opening of the inner cavity, and a corresponding placing mechanism is mounted on the rotating mechanism; the test tube can be adapted to different detection conditions, test tube shells with heating or illumination functions at different electric device mounting positions are selected for classified use, so that better detection is performed, meanwhile, the operation is very convenient, additional equipment cooperation is not needed, and the cost is reduced. And the test tube shells with different functions can be moved by rotating the rotating plate.

Description

Technical Field

[0001] The utility model belongs to the field of biological detection, and specifically relates to a biomarker detection kit. Background Art

[0002] Biomarkers are biochemical indicators that can mark changes or possible changes in the structure or function of systems, organs, tissues, cells and subcellular structures, and have a wide range of uses. Biomarkers can be used to diagnose diseases, determine disease stages, or evaluate the safety and effectiveness of new drugs or new therapies in target populations.

[0003] A biomarker detection kit is a chemical kit used to detect the presence or content of specific molecules or substances in an organism. It contains various chemical reagents, antibodies, probes, etc., which are used to specifically react with the target biomarker.

[0004] The Chinese patent with the authorization announcement number CN210720407U discloses a novel biomarker detection kit, which is provided with a shell; a foam protective layer, which is pasted on the inner surface of the shell; a fixing groove, which is embedded in the inside of the foam protective layer; and at least one beaker groove, which is embedded on the right side of the foam protective layer. The novel biomarker detection kit is provided with multiple protection and protective devices in the box to protect the biomarker detection reagent stick in the box from vibration damage and external pollution, so that it is convenient to carry to various places for biomarker detection.

[0005] The above technical solution has the following defects:

[0006] For biomarkers, different types of biomarkers require different detection requirements. For example, in protein detection, heating treatment may help denature, disaggregate or bind to other molecules of the protein, making it easier to detect; light treatment can help activate fluorescent markers or enhance fluorescent signals for detection and measurement. However, the above technical solutions cannot achieve the adaptation function for different detection requirements. Utility Model Content

[0007] In view of the above defects, the utility model provides a biomarker detection kit, comprising a box body and a box cover hinged therewith, wherein the working surface of the box body is respectively provided with a pipette slot for placing a pipette and a gun tip, a comparison paper slot for placing a comparison card, a beaker slot for placing a beaker, and a test tube slot for placing different test tubes, an inner cavity is provided inside the box body, a rotating mechanism is installed at the opening of the inner cavity, the rotating mechanism comprises two rotating plates, the two rotating plates are respectively rotatably connected to the inner top wall and the inner bottom wall of the inner cavity through a rotating rod, and a corresponding placement mechanism is installed between the two rotating plates through a plurality of fixed columns;

[0008] The placement mechanism includes a test tube shell for fixing the test tube, an operation port is provided on the front of the test tube shell, a placement cavity is provided inside the test tube shell, spring positioning beads for limiting the test tube are installed on the inner side walls of the operation port, a top limiter and a bottom abutment plate are installed on the top and bottom of the placement cavity respectively, and a functional cabin for installing different electrical components is provided inside the placement cavity.

[0009] Furthermore, the test tube shell is truncated cone-shaped, and a sponge pad is fixed to the inner wall of the placement cavity, the sponge pad includes an upper sponge pad and a lower sponge pad, the diameter of the upper sponge pad is smaller than the diameter of the lower sponge pad, the front of the upper sponge pad and the lower sponge pad are both provided with slots for inserting the test tube, the bottom abutment plate is fixed to the inside of the slot of the lower sponge pad by a spring, and the front of the bottom abutment plate is provided with an arc groove that matches the outer surface of the bottom of the test tube.

[0010] Through the above technical solution, the upper sponge pad and the lower sponge pad can clamp and protect the test tube without making direct hard contact with the inner cavity, and the bottom abutment plate is provided so that when taking out the test tube, the bottom of the test tube can be pushed inward. Through spring compression, the test tube rotates with the spring positioning bead as the center, so that the top of the test tube is turned out for easy removal.

[0011] Furthermore, the top stopper and the bottom abutment plate are both made of corrosion-resistant rubber materials, and the top stopper is a spherical surface and contacts the top of the test tube.

[0012] The above technical solution can wrap the test tube and prevent the test tube from shaking inside the test tube shell.

[0013] Furthermore, a mobile power source is installed inside the inner cavity, and the mobile power source is used to supply power to the electrical components inside each functional compartment, and a heat dissipation groove is opened on the top of the box body.

[0014] The above technical solution is used to supply power to various electrical devices to meet different types of detection requirements.

[0015] Furthermore, a group of brush layers is fixed to the opening of the inner cavity.

[0016] The above technical solution has a certain dust-proof effect and prevents the test tube from colliding with the opening edge of the inner cavity when being placed in.

[0017] Furthermore, the box cover is fixed to the box body by a lock, and a groove that fits with the protruding rotating mechanism is provided on one side of the box cover close to the box body, and a pressure pad for pressing the pipette slot, comparison paper slot, beaker slot and test tube slot is also fixed on the right side of the groove.

[0018] Through the above technical solution, the groove will not block the protruding rotating mechanism, and the pressure pad can press the placed pipette, comparison paper, beaker and test tube so as not to cause displacement when picking up and moving.

[0019] Furthermore, the ends of the two rotating rods that are away from each other are both provided with threads, which are respectively threadedly connected to nuts embedded in the inner top wall and inner bottom wall of the inner cavity. The number of turns of the threaded layers opened in the nut makes the rotation angle of the rotating rod 360°.

[0020] Through the above technical solution, the rotation angle is limited without affecting the rotation selection of unused test tube shells. The 360° design can meet the requirements that each test tube shell can be rotated to the opening of the inner cavity for the installation of the test tube, and at the same time, it will not rotate continuously, preventing the entanglement of wires between internal electrical components and mobile power supplies.

[0021] Compared with the prior art, the utility model has the following beneficial effects:

[0022] 1. Pipettes, comparison papers, beakers and test tubes are stored in categories, and test tubes after use are stored separately, which provides good protection whether they are moved or placed;

[0023] 2. It can also be adapted to situations that require different testing conditions. Test tube shells with different electrical device installation locations with heating or lighting functions can be selected for classification and use in order to perform better testing. At the same time, it is also very convenient to operate. No additional equipment is required. The movement of test tube shells with different functions can be achieved by rotating the rotating plate. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the box body and the box cover in the open state in the utility model.

[0025] Figure 2 It is a connection diagram of the rotating mechanism and the placing mechanism in the utility model.

[0026] Figure 3 It is a cross-sectional view of the test tube shell of the utility model from the side.

[0027] Figure 4 It is a schematic diagram of the upper sponge pad and the lower sponge pad in the utility model.

[0028] In the figure: 1. box body; 2. box cover; 31. rotating plate; 32. rotating rod; 33. fixed column; 4. brush layer; 5. placement mechanism; 51. test tube shell; 52. operation port; 53. spring positioning bead; 54. top limiter; 55. bottom abutment plate; 56. sponge pad; 57. placement cavity; 58. functional cabin; 6. groove; 8. pipette slot; 9. comparison paper slot; 10. beaker slot; 11. test tube slot; 12. pressure pad. DETAILED DESCRIPTION

[0029] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the relevant drawings. The drawings provide embodiments of the device. However, the device can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thorough and comprehensive.

[0030] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "set" should be understood in a broad sense, for example, they can be fixedly connected or set, or detachably connected or set, or integrally connected or set. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0031] Example

[0032] like Figure 1-4 As shown, this embodiment provides a biomarker detection kit, including a box body 1 and a box cover 2 hinged thereto by a hinge. In detail, the box cover 2 is fixed to the box body 1 by a lock, and a groove 6 (the length should be slightly larger than the length of the rotating mechanism, so as to adapt to the up and down movement caused by its rotation) is provided on a side of the box cover 2 close to the box body 1, which fits the protruding rotating mechanism. In order to facilitate the use of the rotating mechanism, the front face of the rotating mechanism will exceed the opening face of the inner cavity (correspondingly, the length of the opening should also be slightly larger than the length of the rotating mechanism, so as to adapt to the groove 6). By providing the groove 6, the protruding rotating mechanism will not be blocked. At the same time, a pressure pad 12 for pressing the pipette slot 8, the comparison paper slot 9, the beaker slot 10 and the test tube slot 11 is also fixed to the right side of the groove 6. The pressure pad 12 can press the placed pipette, comparison paper, beaker and test tube, and will not cause displacement when picked up and moved;

[0033] The working surface of the box body 1 is respectively provided with a pipette slot 8 for placing a pipette and a gun tip, a comparison paper slot 9 for placing comparison cardboard, a beaker slot 10 for placing a beaker, and a test tube slot 11 for placing different test tubes, so as to realize the function of classified storage, which is more clear at a glance in the subsequent selection. The box body 1 is provided with an inner cavity, and a group of brush layers 4 are fixed to the opening of the inner cavity, which has a certain dustproof effect and prevents the test tube from colliding with the opening edge of the inner cavity when being placed. The opening of the inner cavity is installed with a rotating mechanism, which includes two rotating plates 31, and the two rotating plates 31 are rotatably connected to the inner top wall and the inner bottom wall of the inner cavity through a rotating rod 32, and a corresponding placement mechanism 5 is installed between the two rotating plates 31 through a plurality of fixed columns 33, so that the function of selecting the placement mechanism 5 can be realized by rotating the rotating mechanism;

[0034] It should be noted that the ends of the two rotating rods 32 that are away from each other are both provided with threads that rotate in the same direction, and are respectively threadedly connected to the nuts embedded in the inner top wall and the inner bottom wall of the inner cavity (the threads in the two nuts are also arranged in the same direction, so as to ensure that the rotating mechanism can move up and down according to the number of thread layers when rotating). The number of turns of the thread layers opened in the nut makes the rotation angle of the rotating rod 32 360°, which is used to limit the rotation angle without affecting the selection of the unused test tube shell 51 for rotation. The 360° design can meet the requirement that each test tube shell 51 can be rotated to the opening of the inner cavity for the installation of the test tube, and at the same time, it will not rotate continuously (i.e., unidirectional rotation), so as to prevent the entanglement of the wires between the internal electrical components and the mobile power supply due to too many rotations (the wires can be bound to the rotating plate 31 at the bottom through the wire tie, and at the same time, it should be ensured that the wires have a certain deformation and stretching length);

[0035] The placement mechanism 5 includes a truncated cone-shaped test tube shell 51 for fixing the test tube (in this embodiment, the number of test tube shells 51 is selected to be 4, and the optimal number for use should be between 3 and 5). An operation port 52 is provided on the front of the test tube shell 51, and a placement cavity 57 is provided inside the test tube shell 51. A sponge pad 56 is fixed to the inner wall of the placement cavity 57. In detail, the sponge pad 56 includes an upper sponge pad and a lower sponge pad. The diameter of the upper sponge pad is smaller than the diameter of the lower sponge pad. The front of the upper sponge pad and the lower sponge pad are both provided with grooves for inserting the test tube. The upper sponge pad and the lower sponge pad can clamp and protect the test tube without making direct hard contact with the inner cavity. The inner side wall of the operation port 52 is installed with a spring positioning bead 53 (i.e., the spring bead used in an umbrella) for limiting the position of the inserted test tube through the return of the internal spring The top and bottom of the placement cavity 57 are respectively provided with a top limit piece 54 and a bottom abutment plate 55. The bottom abutment plate 55 is provided to push the bottom of the test tube inward when taking out the test tube. Through the compression of the spring, the test tube rotates with the spring positioning bead 53 as the center, so that the top of the test tube is turned out for easy taking. The top limit piece 54 and the bottom abutment plate 55 are both made of corrosion-resistant rubber materials. The top limit piece 54 is a spherical surface and contacts with the top of the test tube, so as to wrap the test tube and prevent the test tube from shaking inside the test tube shell 51. In detail, the bottom abutment plate 55 is fixed to the inside of the groove of the lower sponge pad by a spring. The front side of the bottom abutment plate 55 is provided with an arc groove adapted to the outer surface of the bottom of the test tube, which can be attached to the outer surface of the arc surface of the test tube. The inside of the placement cavity 57 is provided with a functional cabin 58 for installing different electrical components.

[0036] It should be noted that a mobile power source is installed inside the inner cavity, and the mobile power source is used to power the electrical components inside each functional compartment 58, and a heat dissipation groove is opened on the top of the box body 1 to achieve a good heat dissipation effect.

[0037] It should be noted that the electrical components select electric heating plates and lamps (LED lamps, xenon lamps, etc.) according to different functions (heating, lighting), and should be adjusted to suit the temperature and light intensity required for detection. They are preferably arranged in a separated manner. When in use, the marker test tube to be reacted can be rotated by rotating the rotating mechanism as needed to select the test tube shell 51 with the corresponding function for use, and the control switch can be set on the surface of the box body 1.

[0038] It should be noted that the structure described in the utility model can be implemented in a variety of different forms and is not limited to the described embodiments. Any equivalent transformations made by ordinary technicians in this field using the contents of the utility model specification and drawings, or directly or indirectly applied to other related technical fields, such as the loading and unloading of other items, are included in the protection scope of the utility model.

Claims

1. A biomarker detection kit, comprising a box body and a box cover hingedly connected thereto, characterized in that: The working surface of the box body is respectively provided with a pipette slot for placing a pipette and a gun tip, a comparison paper slot for placing a comparison card, a beaker slot for placing a beaker, and a test tube slot for placing different test tubes. The box body is provided with an inner cavity, and a rotating mechanism is installed at the opening of the inner cavity. The rotating mechanism includes two rotating plates, and the two rotating plates are respectively rotatably connected to the inner top wall and the inner bottom wall of the inner cavity through a rotating rod, and a corresponding placement mechanism is installed between the two rotating plates through a plurality of fixed columns; The placement mechanism includes a test tube shell for fixing the test tube, an operation port is provided on the front of the test tube shell, a placement cavity is provided inside the test tube shell, spring positioning beads for limiting the test tube are installed on the inner side walls of the operation port, a top limiter and a bottom abutment plate are installed on the top and bottom of the placement cavity respectively, and a functional cabin for installing different electrical components is provided inside the placement cavity.

2. A biomarker detection kit according to claim 1, characterized in that: The test tube shell is in a truncated cone shape, and a sponge pad is fixed to the inner wall of the placement cavity, the sponge pad includes an upper sponge pad and a lower sponge pad, the diameter of the upper sponge pad is smaller than the diameter of the lower sponge pad, the front of the upper sponge pad and the lower sponge pad are both provided with slots for inserting the test tube, the bottom abutment plate is fixed to the inside of the slot of the lower sponge pad by a spring, and the front of the bottom abutment plate is provided with an arc groove adapted to the outer surface of the bottom of the test tube.

3. A biomarker detection kit according to claim 2, characterized in that: The top stopper and the bottom stopper are both made of corrosion-resistant rubber materials. The top stopper is a spherical surface and contacts the top of the test tube.

4. A biomarker detection kit according to claim 1, characterized in that: A mobile power source is installed inside the inner cavity, and the mobile power source is used to supply power to the electrical components inside each functional compartment, and a heat dissipation groove is opened on the top of the box body.

5. A biomarker detection kit according to claim 1, characterized in that: A group of brush layers is fixed to the opening of the inner cavity.

6. A biomarker detection kit according to claim 1, characterized in that: The box cover is fixed to the box body by a lock, and a groove that fits with the protruding rotating mechanism is provided on one side of the box cover close to the box body. A pressure pad for pressing the pipette slot, comparison paper slot, beaker slot and test tube slot is also fixed on the right side of the groove.

7. A biomarker detection kit according to claim 1, characterized in that: The ends of the two rotating rods that are away from each other are both provided with threads, which are respectively threadedly connected to nuts embedded in the inner top wall and inner bottom wall of the inner cavity. The number of turns of the thread layers opened in the nut makes the rotation angle of the rotating rod 360°.

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