Liquid chromatography detection filtering device and detection device

Abstract

The utility model relates to the technical field of chromatographic detection, in particular to a liquid chromatography detection filtering device and a detection device.The filtering device comprises a first pipeline and a conical filter arranged in the first pipeline, and the conical filter comprises a closed top end and an open bottom end; the diameter of the top end is small, and the top end faces the incoming flow direction of liquid in the first pipeline. A detachable first adsorption layer is arranged on the periphery of the outer side of the bottom end of the conical filter; the conical filter is adopted for filtering, a traditional plane type filter screen is replaced, the filtering area is larger, and the conical filter is not prone to being blocked and can be continuously used for a long time. In addition, the first adsorption layer is arranged on the outer side of the bottom end of the conical filter, most of intercepted impurities can flow and be concentrated towards the first adsorption layer due to the flow guide effect of the conical structure and are finally adsorbed and fixed by the first adsorption layer, and it can be guaranteed that the filtering device has a good filtering effect by regularly replacing the first adsorption layer; and the conical filter does not need to be frequently disassembled and cleaned.

Description

Technical Field

[0001] The present application relates to the technical field of chromatography detection, and in particular to a liquid chromatography detection filtering device and a detection device. Background Art

[0002] The filter in the liquid chromatograph is very important in the data detection process. Before sample analysis, filtering to remove the impurities in the sample will significantly extend the service life of the chromatographic column. In the prior art, the filter device of the liquid chromatograph generally adopts a planar filter screen / membrane, or a combination of a planar filter screen / membrane and an adsorbent material. To ensure that there is no clogging, the filter needs to be frequently removed, cleaned and replaced, which is troublesome to maintain. At present, some designs can also use an automated device to regularly clean or replace the filter screen, but this device has a complex structure, high cost, and occupies a large space. Utility Model Content

[0003] The main purpose of the present application is to provide a liquid chromatography detection filter device and a detection device, aiming to solve the problem that the current liquid chromatography filter needs to be frequently disassembled for cleaning and replacement, which is troublesome to maintain.

[0004] In order to solve the above technical problems, the present application provides a liquid chromatography detection filtration device and a detection device, comprising a first pipeline and a conical filter arranged in the first pipeline, wherein the conical filter comprises a closed top end and an open bottom end, wherein the top end has a smaller diameter and faces the flow direction of the liquid in the first pipeline;

[0005] A detachable first adsorption layer is arranged around the outer side of the bottom end of the conical filter.

[0006] Optionally, the first adsorption layer includes activated carbon and an annular filler, the annular filler is sleeved on the outer side of the bottom end of the conical filter, and the activated carbon is filled in the annular filler.

[0007] Optionally, a hollow step stopper is provided at the bottom end of the conical filter, and the first adsorption layer is arranged in the step stopper.

[0008] Optionally, a cylindrical section is provided at the bottom end of the conical filter; the step stopper is arranged around the periphery of the cylindrical section, and the first adsorption layer is filled and arranged between the step stopper and the cylindrical section;

[0009] The first pipeline is provided with an internal thread, and the outer side of the step limiter is provided with an external thread for connecting with the first pipeline.

[0010] Optionally, a second adsorption layer is provided in the conical filter.

[0011] Optionally, the second adsorption layer is arranged at the bottom end of the conical filter.

[0012] Optionally, the device further comprises a second pipeline sealedly connected to the first pipeline, and a limiting ring is provided on the inner wall of one end of the second pipeline connected to the first pipeline.

[0013] Optionally, the first pipeline is connected to the second pipeline via threads or flanges.

[0014] Optionally, the top of the conical filter is a curved surface.

[0015] Based on the same technical concept, the present application also provides a liquid chromatography detection device, including the liquid phase detection filtration device as described above.

[0016] Compared with the prior art, the beneficial effects that can be achieved by this application are:

[0017] The present application adopts a conical filter for filtration, replacing the traditional flat filter screen. The filtration area is larger, the conical filter is not easy to be clogged, and can be used continuously for a long time. In addition, a first adsorption layer is arranged on the outer side of the bottom end of the conical filter. Due to the guiding effect of the conical structure, the intercepted impurities will flow to the first adsorption layer and be finally adsorbed and fixed by the first adsorption layer. Regular replacement of the first adsorption layer can ensure that the filtration device has a good filtration effect without the need to frequently disassemble and clean the conical filter. The filtration device of the present application can effectively reduce the frequency of maintenance and cleaning of the filtration components, while reducing the complexity of maintenance and cleaning operations. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0019] Figure 1 This is a schematic diagram of the structure of a liquid chromatography detection and filtering device in one embodiment of the present application;

[0020] Figure 2 This is a schematic structural diagram of a step stopper and a first adsorption layer in an embodiment of the present application;

[0021] Figure 3 A top view of a step stopper in one embodiment of the present application;

[0022] Figure 4 This is a schematic diagram of the cross-sectional structure of the second pipeline in one embodiment of the present application.

[0023] Explanation of symbols: 1-first pipeline, 2-conical filter, 201-cylindrical section, 202-arc surface, 3-first adsorption layer, 4-step limiter, 401-groove structure, 402-external thread, 403-hollow structure, 5-second pipeline, 501-limiting ring.

[0024] The realization of the purpose, functional features and advantages of this application will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back...) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0027] In the present invention, unless otherwise clearly specified and limited, the terms "connection", "fixation", etc. should be understood in a broad sense. For example, "fixation" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the utility model, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the meaning of "and / or" appearing in the full text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme that satisfies both A and B. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the utility model.

[0029] In the prior art, the filtering device of the liquid chromatograph generally adopts a flat filter screen, or a combination of a flat filter screen and activated carbon. In order to ensure that it does not get clogged, the filtering device needs to be frequently disassembled, cleaned and replaced, which makes maintenance troublesome. In some designs, an automated device can be used to regularly clean or replace the filter screen, but this device has a complex structure, is costly, and occupies a large space.

[0030] To make up for the shortcomings of the existing technology, see Figure 1 An embodiment of the present application provides a liquid chromatography detection filtering device, comprising a first pipeline 1 and a conical filter 2 arranged in the first pipeline 1, wherein the conical filter 2 has a closed end with a smaller diameter, which is the top end; and an open end with a larger diameter, which is the bottom end; the top end faces the flow direction of the liquid in the first pipeline 1;

[0031] A detachable first adsorption layer 3 is disposed around the outer side of the bottom end of the conical filter 2 .

[0032] The present application adopts a conical filter 2 for filtration, replacing the traditional flat filter screen, with a larger filtration area. The conical filter 2 is not easy to be clogged and can be used continuously for a long time. In addition, a first adsorption layer 3 is arranged on the outer side of the bottom end of the conical filter 2. Due to the diversion effect of the conical structure, most of the impurities intercepted will flow to the first adsorption layer 3 and be finally adsorbed and fixed by the first adsorption layer 3. Regular replacement of the first adsorption layer 3 can ensure that the filtration device has a good filtration effect without the need to frequently disassemble and clean the conical filter 2. The filtration device of the present application can effectively reduce the frequency of maintenance and cleaning of the filtration components, while reducing the complexity of maintenance and cleaning operations.

[0033] The conical filter 2 may specifically be a filter screen or a microporous membrane. When a microporous membrane is used, a skeleton may be provided to support the microporous membrane so that the microporous membrane maintains a conical shape.

[0034] As an optional embodiment of the present application, the first adsorption layer 3 includes activated carbon and an annular filler, the annular filler is sleeved on the outside of the bottom end of the conical filter 2, and the activated carbon is filled in the annular filler. The first adsorption layer 3 of this embodiment is designed to be a component that is easy to replace and disassemble. Activated carbon is a common adsorption and impurity removal material. The porous structure of activated carbon provides a large surface area, making it very easy to absorb and collect impurities. All molecules have mutual attraction, and a large number of molecules on the pore wall of activated carbon can generate strong attraction, thereby achieving the purpose of attracting impurities in the medium into the pore size.

[0035] As a preferred embodiment, the activated carbon can be designed as a multilayer structure with decreasing pore sizes when filled, that is, the pore size of the activated carbon at the end where the liquid first contacts is larger, and the pore size of the activated carbon at the end where the liquid contacts is smaller, forming a hierarchical filtration with better filtration effect and can fully utilize the adsorption capacity of the activated carbon.

[0036] In another embodiment, the first adsorption layer 3 may also be an annular filler filled with other adsorption materials, such as molecular sieves, silica gel and activated alumina, etc. Since different substances have different chemical properties, different adsorbents may need to be used for adsorption and filtration. Therefore, the present application designs a detachable first adsorption layer 3, which can be conveniently replaced with different adsorption materials according to different solutions to be detected, and can be used for the detection of multiple solutions.

[0037] In order to facilitate the installation of the first adsorption layer 3, as an optional implementation of the present application, see Figure 2 The bottom of the conical filter 2 is provided with a step stopper 4, and the first adsorption layer 3 is arranged in the step stopper 4. The step stopper 4 is also annular, and the longitudinal section is an L-shaped structure, which is fixedly connected to the bottom of the conical filter 2 and forms a groove structure 401 with the conical filter 2, and the first adsorption layer 3 is embedded and placed in the groove structure 401. Figure 3 Obviously, the upper plane of the step limiter 4 needs to be designed as a hollow structure 403 to allow the liquid to pass through.

[0038] As an optional implementation of the present application, see Figure 1-2 The bottom end of the conical filter 2 is provided with a cylindrical section 201, that is, the conical filter 2 includes a conical section and a cylindrical section 201, and the cylindrical section 201 is connected to the end of the conical section with a larger diameter;

[0039] The step stopper 4 is arranged around the periphery of the cylindrical section 201 , and an external thread 402 for connecting to the first pipeline 1 is provided on the outer side of the step stopper 4 ; the first adsorption layer 3 is filled and arranged between the step stopper 4 and the cylindrical section 201 .

[0040] The step stopper 4 is fixed to the conical filter 2 , and an internal thread is provided on the first pipeline 1 , so that the conical filter 2 can be installed in the first pipeline 1 through the step stopper 4 .

[0041] As an optional embodiment of the present application, a second adsorption layer is provided in the conical filter 2. The second adsorption layer also adopts the form of a filler plus activated carbon (or other adsorption materials), wherein the structure of the filler is designed to be a frustum according to the shape of the inner wall of the conical filter 2, that is, it matches and fits with the conical filter 2. After the solution is filtered through the conical filter 2, it is then adsorbed and filtered through the second adsorption layer, which can effectively improve the filtering effect.

[0042] As an optional embodiment of the present application, the second adsorption layer is arranged at the bottom of the conical filter 2. That is, when the first adsorption layer 3 is arranged at the periphery of the bottom of the conical filter 2, the first adsorption layer 3 and the second adsorption layer are on the same cross section. The second adsorption layer can also be easily disassembled and replaced on time.

[0043] As an optional implementation of the present application, see Figure 4 The device further comprises a second pipeline 5 which is sealedly connected to the first pipeline 1, and a limiting ring 501 is provided on the inner wall of the end of the second pipeline 5 connected to the first pipeline 1. After the second pipeline 5 is connected to the first pipeline 1, the limiting ring 501 can stop the first adsorption layer 3 and / or the second adsorption layer, and the first adsorption layer 3 and the second adsorption layer are fixed in the pipeline under the action of the limiting ring 501. After the second pipeline 5 is separated from the first pipeline 1, the first adsorption layer 3 and the second adsorption layer which have lost their limiting position can be directly taken out, and the disassembly is convenient and quick.

[0044] As an optional embodiment of the present application, the first pipeline 1 is connected to the second pipeline 5 by threads or flanges. If threaded connection is selected, an external thread 402 is provided on the outside of the connection end of the first pipeline 1, and an internal thread is provided on the inside of the connection end of the second pipeline 5.

[0045] As an optional implementation of the present application, see Figure 2 In order to better play the role of guiding and make more impurities flow to the first adsorption layer 3, the end surface of the top of the conical filter 2 is designed as an arc surface 202. If the end surface of the conical filter 2 with a smaller diameter is a plane, impurities will accumulate on this plane after working for a long time and the impurities cannot flow to the first adsorption layer 3, which will lead to a decrease in the filtering effect.

[0046] Based on the same inventive concept, the present application also provides a liquid chromatography detection device, including the above-mentioned liquid phase detection filtration device.

[0047] Those skilled in the art will appreciate that the embodiments described herein are intended to help readers understand the principles of the present invention, and should be understood that the protection scope of the present invention is not limited to such specific statements and embodiments. Those skilled in the art can make various other specific variations and combinations based on the technical inspirations disclosed in the present invention without departing from the essence of the present invention, and these variations and combinations are still within the protection scope of the present invention.

Claims

1. A liquid chromatography detection filter device, characterized in that: It comprises a first pipeline and a conical filter arranged in the first pipeline, wherein the conical filter comprises a closed top end and an open bottom end, and the top end faces the flow direction of the liquid in the first pipeline; A detachable first adsorption layer is arranged around the outer side of the bottom end of the conical filter.

2. A liquid chromatography detection and filtering device according to claim 1, characterized in that: The first adsorption layer comprises activated carbon and an annular filler, the annular filler is sleeved on the outer side of the bottom end of the conical filter, and the activated carbon is filled in the annular filler.

3. A liquid chromatography detection and filtering device according to claim 1, characterized in that: A hollow step stopper is provided at the bottom end of the conical filter, and the first adsorption layer is arranged in the step stopper.

4. A liquid chromatography detection and filtering device according to claim 3, characterized in that: The bottom end of the conical filter is provided with a cylindrical section; The step stopper is arranged around the periphery of the cylindrical section, and the first adsorption layer is filled and arranged between the step stopper and the cylindrical section; The first pipeline is provided with an internal thread, and the outer side of the step limiter is provided with an external thread for connecting with the first pipeline.

5. A liquid chromatography detection and filtering device according to claim 1, characterized in that: A second adsorption layer is arranged in the conical filter.

6. A liquid chromatography detection and filtering device according to claim 5, characterized in that: The second adsorption layer is arranged at the bottom end of the conical filter.

7. A liquid chromatography detection and filtering device according to claim 1, characterized in that: The device also includes a second pipeline sealedly connected to the first pipeline, and a limiting ring is provided on the inner wall of one end of the second pipeline connected to the first pipeline.

8. A liquid chromatography detection and filtering device according to claim 7, characterized in that: The first pipeline is connected to the second pipeline via threads or flanges.

9. A liquid chromatography detection and filtering device according to claim 1, characterized in that: The top end of the conical filter is an arc-shaped surface.

10. A liquid chromatography detection device, characterized in that: It comprises the liquid phase detection filtering device as described in any one of claims 1 to 9.

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