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2 results about "Bradykinin receptor" patented technology
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The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin. There are two Bradykinin receptors: the B₁ receptor and the B₂ receptor.
Antibodies against bradykinin B1 receptor ligands
To provide antibodies that specifically bind to Kallidin or des-Arg10-Kallidin.SOLUTION: The invention provides an isolated monoclonal antibody or antigen binding fragment thereof configured to: a) bind specifically to Kallidin or des-Arg10-Kallidin but not specifically to Bradykinin or des-Arg9-Bradykinin; b) specifically bind to Kallidin or des-Arg10-Kallidin with a KD of less than 1×10-10 M; c) specifically bind to Kallidin or des-Arg10-Kallidin with a Koff of less than 1×104 s-1; and / or d) specifically bind to Kallidin or des-Arg10-Kallidin and inhibit binding to the bradykinin B1 receptor.SELECTED DRAWING: None
Owner:SANOFI SA(FR)
Bradykinin receptor active peptide and use thereof in promoting hair regeneration
Provided are a bradykinin receptor active peptide and a use thereof in promoting hair regeneration. Further provided are a composition comprising the bradykinin receptor active peptide, a pharmaceutical preparation, a kit, and a preparation method for the bradykinin receptor active peptide. The bradykinin receptor active peptide has a good hair regeneration effect and safety, and has clinical application prospects.
Owner:FUDAN UNIVERSITY