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2results about How to "Good response controllability" patented technology

Polyamide elastomer raw material composition and application thereof, polyamide elastomer and preparation method thereof

The invention relates to the field of macromolecules, in particular to a polyamide elastomer raw material composition and application thereof, polyamide elastomer and a preparation method thereof. The raw material composition contains polyamide and polyether, wherein at least one end-capping group in the polyamide is an amino-terminated group; at least one end-capping group in the polyether is an ester group. When the raw material composition is used for preparing the polyamide elastomer, the advantages of high reaction speed, high production efficiency and the like are achieved, the reaction controllability is high, the molecular weight of the product is large, and the type, molecular weight and structure of the soft segment can be adjusted according to application requirements, so that the performance of the elastomer is effectively regulated and controlled.
Owner:PETROCHINA SHANGHAI ADVANCED MATERIALS RESEARCH INSTITUTE CO LTD +1

6-methyl-3, 5-dioxocapryloyl coenzyme A as well as preparation method and application thereof

ActiveCN121851075Aprove correctnessAccurate acyl transferSugar derivativesSugar derivatives preparationChemical synthesisButyrate
The invention relates to a preparation method and application of 6-methyl-3, 5-dioxocapryloyl coenzyme A. According to the preparation method, 2-methylbutyric acid serves as a starting raw material, the 6-methyl-3, 5-dioxocapryloyl coenzyme A is chemically synthesized through the steps of activation, condensation, coenzyme A coupling and the like, and the structure and purity of the 6-methyl-3, 5-dioxocapryloyl coenzyme A are identified through the technologies of LC-MS / MS, 1HNMR and the like. The nine-carbon coenzyme A is successfully prepared and identified through a chemical synthesis method for the first time, the core problem that an intermediate is unstable and cannot be obtained in vitro is solved, and a stable substrate is provided for in-vitro acyl transfer; the QS-21 in-vitro acyl transfer reaction is realized for the first time, an in-vitro catalytic system of a chemical synthesis intermediate and an insect cell expression enzyme is established, and a foundation is laid for development of a QS-21 total synthesis process.
Owner:WUHAN TANGZHI PHARM CO LTD +1