The present invention provides an
ion analysis device, comprising: a first
ion source for providing
analyte ions; a second
ion source for providing auxiliary ions; the positive and negative polarities of the auxiliary ions are opposite to those of the
analyte ions, the ion cloud of the auxiliary ions overlaps with the ion cloud of the
analyte ions in
spatial distribution, and at least part of the analyte ions do not produce a
chemical reaction with the auxiliary ions; an ion analyzer for analyzing the analyte ions; an ion transmission device, located between the first
ion source and the ion analyzer, for transmitting the analyte ions into the ion analyzer and refusing the auxiliary ions from entering the ion analyzer. The present invention can reduce or eliminate the
space charge effect between a large number of analyte ions, thereby improving the ion analysis performance under such conditions, such as sensitivity, resolution, etc.