The invention relates to the technical field of exercise, in particular to a cardiovascular medicine clinical exercise device which comprises two hand-cranking mechanisms, each hand-cranking mechanism comprises a fixed shell, one ends of the two fixed shells are fixedly connected, the top surfaces of the fixed shells are rotatably connected with a shaft rod, and the top end of the shaft rod is rotatably connected with a rotating disc. The bottom end of the shaft rod penetrates through the top face of the fixing shell and extends into the fixing shell, a first rotating bevel gear is fixedly connected to the bottom end of the shaft rod, a first movable shell part is arranged on the bottom face of the other end of the fixing shell, and a first massage mechanism is arranged in the first shell part. According to the device, through the arrangement of the first massage mechanism and the second massage mechanism, two hands drive the two rotating discs to rotate to exercise the upper limbs, and while the rotating discs rotate, the first massage mechanism and the second massage mechanism are driven to knead the two sides of the legs, activate blood, promote menstruation, stimulate the leg nerves, reduce the numbness of the legs and increase the blood circulation of the legs; the upper limbs are exercised, and meanwhile the legs are massaged.