Medicinal composition for treating menoxenia and preparation process thereof

A technology of irregular menstruation and composition, which is applied in the direction of drug combination, testing of pharmaceutical preparations, pharmaceutical formulations, etc.

Inactive Publication Date: 2009-02-11
北京新康仁德医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the dosage forms of drugs used to treat menstrual disorders still need to be further improved to meet the requirements of clinical medication.

Method used

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  • Medicinal composition for treating menoxenia and preparation process thereof
  • Medicinal composition for treating menoxenia and preparation process thereof
  • Medicinal composition for treating menoxenia and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0129] Motherwort 500kg Sucrose 100kg Aspartame 1.5kg

[0130] Citric acid 4kg Sodium alginate 10kg Potassium sorbate 1.0kg.

[0131] For the above raw material, take motherwort, add 8 times the amount of water and decoct 3 times, the first time for 2 hours, the second time for 1.5 hours, the third time for 1 hour, filter, combine the filtrates, concentrate to 250L, cool, add the same amount Stir well, let it stand for 24 hours, filter, the filtrate recovers ethanol under reduced pressure and concentrates to a thick paste, dilutes to 500L with water, refrigerates for 24 hours, filters, and concentrates the filtrate to a clear paste with a relative density of 1.15 at 60°C , dilute with water, filter; take another sucrose, aspartame, citric acid and potassium sorbate, add water to heat to dissolve, filter, add to the above liquid, stir well, add sodium alginate, add water, stir and boil , keep warm at 90°C, and make a gel with a relative density of 1.15 at 90°C.

Embodiment 2

[0133] Motherwort 450kg Sucrose 150kg Aspartame 0.5kg

[0134] Citric acid 6kg, sodium alginate 7kg, potassium sorbate 1.6kg.

[0135] The above-mentioned raw materials, motherwort, add 10 times the amount of water to decoct 3 times, the first time for 3 hours, the second time for 3 hours, the third time for 1 hour, filter, combine the filtrate, concentrate to 300L, cool, add the same amount Stir well, let it stand for 20 hours, filter, the filtrate recovers ethanol under reduced pressure and concentrates to a thick paste, dilutes to 600L with water, refrigerates for 26 hours, filters, and concentrates the filtrate to a clear paste with a relative density of 1.10 at 50°C , dilute with water, filter; take another sucrose, aspartame, citric acid and potassium sorbate, add water to heat to dissolve, filter, add to the above liquid, stir well, add sodium alginate, add water, stir and boil , kept at 80°C to make a gel with a relative density of 1.05 at 95°C.

Embodiment 3

[0137]Motherwort 550kg Sucrose 60kg Aspartame 2.0kg

[0138] Citric acid 2kg Sodium alginate 12kg Potassium sorbate 0.5kg.

[0139] For the above raw material, take motherwort, add 9 times the amount of water and decoct 3 times, the first time for 2 hours, the second time for 1 hour, the third time for 2 hours, filter, combine the filtrate, concentrate to 260L, cool, add the same amount of ethanol, stir well, stand still for 25 hours, filter, the filtrate is decompressed to recover ethanol and concentrate to a thick paste, add water to dilute to 600L, refrigerate for 22 hours, filter, and the filtrate is concentrated to 50-70°C with a relative density of 1.15 Clear ointment, add water to dilute, filter; take another sucrose, aspartame, citric acid and potassium sorbate, add water to heat to dissolve, filter, add to the above liquid medicine, stir well, add sodium alginate, add water and stir And boil it, keep it warm at 85°C, and make a gel with a relative density of 1.10 at ...

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Abstract

The invention discloses a medicine combination for treating irregular menstruation caused by blood stasis, postpartum lochiorrhea, few meridians and vessels, nonstopping dripping wet, postpartum hemorrhage mecism; postpartum uterine subinvolution and preparation technology and quality control methods. The combination is fiated by leonurus, sucrose, aspartame, citric acid, sodium alginate, potassium sorbate and so on. The combination is made into gelata through adding pharmaceutical acceptable induing-form agents by conventional technology directly or indirectly, the combinations possess the effect of promoting blood circulation to restore menstrual flow.

Description

technical field [0001] The invention relates to a pharmaceutical composition, a preparation method and a quality detection method thereof, in particular to a pharmaceutical composition for treating irregular menstruation, a preparation method and a quality detection method thereof. Background technique [0002] Menstrual disorders are one of the common symptoms in gynecology. Those whose menstrual flow and interval are different from the normal menstrual cycle are included in this category. The common types are menorrhagia, menorrhagia, menorrhagia, and menstrual thinning. The cause of menstrual disorders is mainly due to endocrine dysfunction, but it can also be caused by systemic diseases or local diseases of reproductive organs. "Irregular menstruation" in traditional Chinese medicine is equivalent to a part of "menstrual disorders" in modern medicine, excluding abnormal menstruation caused by internal and external genital organic lesions. The disease is mainly caused b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/533A61K9/00A61P15/00G01N30/02G01N21/33G01N33/15
Inventor 徐新盛
Owner 北京新康仁德医药技术开发有限公司
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