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New use of tizanidine and its derivatives in preparing medicine for treating anxiety disorder

A technology of tizanidine and tizanidine hydrochloride, which is applied in the field of medicine and can solve the problems that have not yet been reported on the treatment of anxiety by tizanidine and its derivatives.

Active Publication Date: 2010-12-22
SICHUAN CREDIT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] There are no relevant reports on the treatment of anxiety disorders by tizanidine and its derivatives

Method used

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  • New use of tizanidine and its derivatives in preparing medicine for treating anxiety disorder
  • New use of tizanidine and its derivatives in preparing medicine for treating anxiety disorder
  • New use of tizanidine and its derivatives in preparing medicine for treating anxiety disorder

Examples

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Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0026] Tizanidine hydrochloride 0.0019mol (about 0.5g tizanidine, made into 1000 tablets)

[0027] Starch 200g

[0028] Microcrystalline Cellulose 5g

[0029] After the tizanidine hydrochloride and starch are mixed uniformly by the method of equal increase, then mixed with microcrystalline cellulose, granulated and compressed into tablets to obtain tablets; or packed into capsules to obtain capsules.

Embodiment 2

[0030] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0031] Tizanidine hydrochloride 0.0019mol (about 0.5g tizanidine, made into 1000 capsules)

[0032] Starch 200g

[0033] Microcrystalline Cellulose 5g

[0034] After the tizanidine hydrochloride and the starch are uniformly mixed by an equal-volume increasing method, then mixed with the microcrystalline cellulose, granulated, and packed into capsules, the capsules are obtained.

Embodiment 3

[0035] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0036] Tizanidine hydrochloride 0.0039mol (about 1g tizanidine, 1000 pills)

[0037] Flavor 1.5g

[0038] Distilled water 500ml

[0039] Starch 80g

[0040] Dextrin 20g

[0041] Mix tizanidine hydrochloride and starch uniformly by the method of equal increase, then mix with dextrin and flavoring agent, make pills, and dry to obtain.

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Abstract

The invention relates to a novel application of both tizanidine and a ramification of tizanidine, in particular to the novel application of both tizanidine and the tizanidine ramification in the process of preparing medicines used for treating anxiety disorder. The invention also provides an application of a medicine compound containing tizanidine and the tizanidine ramification in the process ofpreparing medicines used for treating anxiety disorder. As a central muscle relaxants pain-releasing medicine, tizanidine not only can release the pain but also can solve the anxiety of pain sufferers.

Description

technical field [0001] The invention relates to a new application of tizanidine and derivatives thereof, in particular to a new application of tizanidine for treating anxiety, and belongs to the field of medicine. Background technique [0002] Anxiety is an emotional state that is a mental and physical response to anticipation of illusory or imagined danger. Due to the accelerated pace of modern life, competition is becoming increasingly fierce. Causes many people to experience varying degrees of anxiety. Mild patients only feel uneasiness and fear in their hearts, and most of them are accompanied by hyperautonomous nervous system function, and they will experience rapid heart rate, chest tightness, sweating, fatigue, and sleep disorders. In severe anxiety, in addition to the general symptoms of anxiety, there will also be frightening feelings such as hyperventilation symptoms, a sense of dying, a sense of fainting, a sense of losing control, and a sense of going crazy. A...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P25/22A61K9/16A61K9/08A61K9/48A61K31/433A61K9/10A61K9/20
Inventor 陈刚陈功政刁健代竹青
Owner SICHUAN CREDIT PHARMA
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