Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area

A three-dimensional conformal, heavy ion beam technology is applied in the field of devices for the irradiation of heavy ion beams in the biomedical field, and can solve the problems of reducing beam quality by scatterers, reducing the proportion of healthy tissue, and low conformity, etc. To achieve the effect of reducing the probability of normal tissue complications, reducing normal tissue complications, and high conformity

Active Publication Date: 2010-04-21
国科离子医疗科技有限公司
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Problems solved by technology

[0004] In order to give full play to the advantages of heavy ion beams in radiotherapy, the purpose of the present invention is to overcome the shortcomings of the current two-dimensional conformal irradiation therapy, such as the low degree of conformation and the reduction of beam quality by scatterers. We based on passive beam distribution The system provides a device for performing three-dimensional conformal irradiation therapy on the tumor target area with heavy ion beams, so that the high-dose Bragg peak area of ​​the heavy ion beam falls completely on the tumor target area, and the proportion of healthy tissues irradiated by the high-dose area greatly reduced

Method used

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  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area
  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area
  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area

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Embodiment 1

[0026] The present invention takes the CR39 slice of the solid nuclear track detector chemically etched after irradiation as an example to illustrate the three-dimensional conformal irradiation of the target area composed of the CR39 slice by the heavy ion beam.

[0027] Using the 80.55MeV / u carbon ion beam provided by the Lanzhou Heavy Ion Research Facility (HIRFL) of the Institute of Modern Physics, Chinese Academy of Sciences, we used the HIRFL superficial tumor heavy ion therapy terminal equipped with a passive beam distribution system for the scanning magnet of the present invention. The beam Bragg broadening was tested by the uniform irradiation field and mini ridge filter formed by the system.

[0028] like figure 1 As shown in the figure, the device for applying three-dimensional conformal irradiation therapy to tumor target area by heavy ion beam includes a scanning magnet system 1, a beam monitoring system 2, a mini ridge filter 3, a range shifter 4, and a multi-leaf...

Embodiment 2

[0033] Using the device for performing three-dimensional conformal irradiation therapy on tumor target areas with heavy ion beams described in Example 1, the present invention uses tissue equivalent material CR39 thin slices (thickness 0.66mm, water equivalent length coefficient 1.061) to stack the phantom As an example, to illustrate the three-dimensional conformal irradiation of carbon ion beams on a target area composed of CR39 flakes.

[0034] All the devices in the present invention were integrated to perform three-dimensional conformal irradiation on the phantom stacked by tissue equivalent material CR39 slices, and the tumor tomography was seven slices, such as Figure 7 As shown in the figure on the left side of the middle, along the beam penetration direction, the tumor slices are circular with diameters of 10mm, 20mm, 30mm, 40mm, 30mm, 20mm and 10mm. In the irradiation, the scanning frequency of the scanning magnet system in the 1x direction is 75Hz, the scanning fre...

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Abstract

The invention relates to a device used in 3-D conformal radiotherapy to gross tumor volume with heavy ion beams, comprising a magnet scanning system, a beam monitor system, a mini-ridge filter, a range shifter, a multi-leaf collimator and a patient body surface compensator, which are sequentially arranged on the body surface of the patient. The centers of the components and the center of the grosstumor volume are located at the beam axis. The invention overcomes the defects that the conformality is low and the scatterer impairs beam quality in current 2-D conformal radiotherapy by heavy ion beams based on a passive beam flow distribution system, and adopts 3-D conformal irradiation without the scatterer needed in current 2-D conformal radiotherapy, thus improving conformality in the therapy to the gross tumor volume with heavy ion beams. The invention can protect the health organs around the gross tumor volume to the largest extent and reduce incidence of disease at the normal organswithout reducing the rate of using large quantity of Bragg peak to efficiently kill the cells in the gross tumor volume, thus improving curative effect of the heavy ion beams.

Description

technical field [0001] The invention relates to a device for applying heavy ion beam irradiation in the field of biomedicine, in particular to a device for performing three-dimensional conformal irradiation therapy on a tumor target area with a heavy ion beam. Background technique [0002] Heavy ion beams are known as the most ideal radiation therapy rays for the 21st century. The device can realize the three-dimensional conformal irradiation of the heavy ion beam to the tumor target area. Three-dimensional conformal irradiation technology can give full play to the advantages of heavy ion beam in cancer treatment, kill tumor cells in the target area to the greatest extent, and protect the healthy tissue around the tumor target area from damage to the greatest extent, and reduce the incidence of normal tissue complications. disease probability, improve the conformity of heavy ion beam therapy, thereby improving the efficacy of heavy ion beam radiation therapy. [0003] The ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/00
Inventor 李强肖国青戴中颖
Owner 国科离子医疗科技有限公司
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