A kind of tea oral tablet and preparation method thereof
A technology for oral tablets and theaflavins, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. functional effect
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[0027] The preparation method of above-mentioned tea oral tablet, comprises the following steps:
[0028] 1. Take materials according to the following mass percentages:
[0029] Theaflavins 5-30%
[0030] Tea polyphenols 15-30%
[0031] Filler 20-60%
[0032] Flavor 5-10%
[0033] Disintegrant 10-15%
[0034] Binder 1-3%.
[0035] 2. Mix theaflavins, tea polyphenols, fillers, flavoring agents and disintegrants, crush them, pass through a 40-100 mesh sieve, and mix in a mixer for 20-50 minutes;
[0036] 3. Add ethanol with a volume ratio of 95% to moisten and granulate, pass through a 16-40 mesh sieve; dry at 40-70°C for 2-5 hours, granulate through a 40-100 mesh sieve, and cool.
[0037] 4. After the granulation, the material is added to the binder and mixed in the sugar coating machine for 20-40 minutes.
[0038] 5. Compression molding by tablet press.
Embodiment 1
[0041] Take 20 parts of theaflavins, 25 parts of tea polyphenols, 38 parts of xylitol, 6 parts of vitamin C, and 10 parts of microcrystalline cellulose, mix and pulverize them, and pass through a 40-mesh sieve. Mix in a mixer for 20 minutes, add 95% ethanol to granulate, pass through a 16-mesh sieve, dry at 50°C for 4 hours, granulate and cool at 80-mesh. After adding 1 part of magnesium stearate for mixing, it is mixed with the granulated material in a water chestnut icing machine for 30 minutes. Tablet press compression molding.
Embodiment 2
[0043] Take 16 parts of theaflavins, 27 parts of tea polyphenols, 46 parts of mannitol, 5 parts of citric acid, and 4 parts of croscarmellose sodium, mix and pulverize them, and pass through a 40-mesh sieve. Mix in a mixer for 30 minutes, add 95% ethanol to granulate, pass through a 16-mesh sieve, dry at 60°C for 3 hours, granulate and cool at 70-mesh. After adding 2 parts of pregelatinized starch and mixing, then mix with the whole material in a water chestnut sugar coating machine for 30 minutes. Tablet press compression molding.
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