Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for preparing cellulose microspheres

A technology of cellulose microspheres and cellulose solution, applied in the preparation of microspheres, microcapsule preparations, etc., can solve the problems of complex post-processing, toxic and harmful, and residual groups are prone to agglomeration, and achieve simple post-processing. , not easy to agglomerate, the effect of simple preparation process

Active Publication Date: 2010-12-22
武汉工大科技园发展有限公司
View PDF2 Cites 28 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The problem to be solved by the present invention is to propose a preparation method of cellulose microspheres in view of the prior art. The obtained cellulose microspheres have good dispersibility, the product post-processing technology is simple, and large-scale, low-cost production and preparation can be realized. It o

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing cellulose microspheres

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Pre-cool NaOH / urea aqueous solution to -12°C as a solvent, add cellulose and stir to dissolve at high speed, and finally centrifuge at low speed to remove impurities to obtain a cellulose solution with a concentration of 0.01wt%. Stir 10ml of the above cellulose solution for 30 minutes. After 10 minutes of ultrasonication, put it into the injection tube, add a 3mm diameter nozzle, and connect the nozzle to the positive pole of the high-voltage power supply as the anode, use aluminum foil as the conductive plate to connect with the negative pole of the high-voltage power supply, and adjust the working distance between the positive and negative electrodes to 5cm. The flow rate of the cellulose solution sprayed by the nozzle is 0.1ml / h, electrostatically sprayed at a voltage of 10kV, the cellulose solution is sprayed out from the electrospinning equipment in a fine stream, and the dilute hydrochloric acid solidified solution is placed on the conductive plate, and the average...

Embodiment 2

[0021] Precool NaOH / thiourea aqueous solution to -5°C as a solvent, add cellulose and stir to dissolve at high speed, and finally centrifuge at low speed to remove impurities to obtain a cellulose solution with a concentration of 1wt%. Stir 10ml of the above cellulose solution for 30 minutes. After 10 minutes of ultrasound, add it into the injection tube, install a 2mm diameter nozzle, and connect the nozzle to the positive pole of the high-voltage power supply as the anode, use aluminum foil as the conductive plate to connect with the negative pole of the high-voltage power supply, and adjust the working distance between the positive and negative electrodes to 10cm. The flow rate of the cellulose solution is 1ml / h, electrostatically injected under the voltage of 20kV, the cellulose solution is atomized and sprayed out from the electrospinning equipment, and the dilute sulfuric acid solidification solution is placed on the conductive plate (metal plate) to receive, and the avera...

Embodiment 3

[0023] Pre-cool LiOH / urea aqueous solution to -12°C as a solvent, add cellulose and stir to dissolve at high speed, and finally centrifuge at low speed to remove impurities to obtain a cellulose solution with a concentration of 3wt%. Stir 10ml of the above cellulose solution for 30 minutes and ultrasonically After 10 minutes, add it to the injection tube, install a 1mm diameter nozzle, and connect the nozzle to the positive pole of the high-voltage power supply as the anode, use aluminum foil as the conductive plate to connect with the negative pole of the high-voltage power supply, and adjust the working distance between the positive and negative electrodes to 20cm. The flow rate of the cellulose solution is 5ml / h, and it is electrostatically sprayed at a voltage of 30kV. The cellulose solution is atomized and sprayed out from the electrospinning equipment, and the mixed solidification solution of dilute hydrochloric acid and dilute sulfuric acid is placed on the conductive pla...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
The average particle sizeaaaaaaaaaa
The average particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention relates to a method for preparing cellulose microspheres, which comprises the following steps of: 1) pre-cooling aqueous solution of alkali/urea or/and aqueous solution of alkali/thiourea serving as a solvent to a low temperature of between 5 DEG C below zero and 12 DEG C below zero, then adding cellulose into the solvent, stirring the mixture for dissolution at a low temperature and a high speed, and finally removing impurities by low-speed centrifugal deaeration to obtain cellulose solution; and 2) performing electrostatic spraying under the action of a high-voltage electric field, and finally forming the regenerative cellulose microspheres. The method has the advantages that: 1) the cellulose microspheres are not easily agglomerated and can be uniformly dispersed; 2) the preparation process is simple; 3) any other auxiliary agent such as emulsifying agent, dispersant or the like is not needed, the prepared product is pure, the post treatment is simple, and the product particularly has superiority in the biotechnology application field; 4) large-scale and low-cost production can be performed by using the high-voltage electrostatic spraying technology; and 5) the shape and the size of the microspheres are controlled by changing the process conditions such as concentration of the molecular solution, electrostatic spraying condition and the like.

Description

technical field [0001] The invention belongs to the technical field of functional materials, and in particular relates to a preparation method of cellulose microspheres. Background technique [0002] Science and technology in the 21st century have tended towards renewable raw materials, environmentally friendly and sustainable processes and methods. The theme of the 239th Annual Meeting of the American Chemical Society is "Chemistry for a Sustainable World". Attention has been paid to biodegradable and biocompatible materials prepared from renewable resources. Cellulose is one of the most abundant and renewable natural resources on the earth. It is cheap, degradable and does not pollute the environment. Therefore, all countries in the world attach great importance to the research and development of cellulose. Cellulose is composed of cellobiose repeating units via β-(1 4) Linear polymers connected by -D-glycosidic bonds. The hydroxyl groups on each anhydroglucose unit ar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08L1/02C08J3/09B01J13/02
Inventor 喻发全罗晓刚吴元欣
Owner 武汉工大科技园发展有限公司