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Application of compound mylabris traditional Chinese medicine composition and its preparation in preparing medicine for treating depression

A technology for depression and composition, which is applied in the field of compound mylabris traditional Chinese medicine composition and its preparation in the preparation of drugs for treating depression, and can solve the problems of patent literature and research reports on the therapeutic effect of compound mylabris preparation on depression.

Active Publication Date: 2015-09-09
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although previous studies have shown that the compound mylabris preparation can be used to prepare drugs for treating tumors, regulating immunity and other diseases, there are no patent documents and research reports on the therapeutic effect of the compound mylabris preparation on depression.

Method used

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  • Application of compound mylabris traditional Chinese medicine composition and its preparation in preparing medicine for treating depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] (1) Weigh the raw materials according to the following ratio:

[0064] Mylabris 3.97g, Ginseng 9.92g, Astragalus 49.58g, Acanthopanax 49.58g, Sanleng 15.83g, Scutellaria barbata 59.5g, Curcuma 15.83g, Cornus officinalis 19.83g, Ligustrum lucidum 19.83g, bear bile powder 0.4g, licorice 9.92g

[0065] (2) Preparation method:

[0066] The above eleven flavors, except bear bile powder, ginseng, dogwood, Ligustrum lucidum, and Scutellaria barbata are crushed into fine powder, sieved, and set aside; Mylabris is extracted by soaking in chloroform three times, 95.2ml each time, soaked for 72 hours, combined Extract, recover chloroform, concentrate to a thick paste; add water and decoct the other five flavors such as Astragalus membranaceus for three times, the first time for 3 hours, the second time for 1.5 hours, and the third time for 1 hour, combine the decoctions, filter, and concentrate the filtrate to relative The density is about 1.20 (80°C); after the bear bile powder...

Embodiment 2

[0068] (1) Weigh the raw materials according to the following ratio:

[0069] Mylabris 0.6g, Ginseng 1.5g, Astragalus 7.5g, Acanthopanax 7.5g, Trigonum 2.4g, Banzhilian 9.0g, Curcuma 2.4g, Cornus officinalis 3g, Ligustrum lucidum 3g, Bear bile powder 0.05g, Licorice 1.5g

[0070] (2) Preparation method:

[0071] Eleven flavors in the recipe, except for bear bile powder, crushed mylabris into 60-mesh fine powder, extracted 4 times with water, added 22 times the amount of water for the first time, soaked for 30 minutes, extracted for 2 hours, and added 15 times the amount for the second time water, extract for 1 hour, add 12 times the amount of water for the third time, extract for 1 hour, add 10 times the amount of water for the fourth time, extract for 1 hour, filter, and combine the filtrate; the remaining 9 flavors of ginseng and other ginseng are extracted with water for 3 times , add 15 times the amount of water for the first time, soak for 1 hour, extract for 4 hours, ad...

Embodiment 3

[0073] (1) Weigh the raw materials according to the following ratio:

[0074] Mylabris 6.0g, Ginseng 15g, Astragalus 100g, Acanthopanax 100g, Trigonum 24g, Banzhilian 100g, Curcuma 24g, Cornus officinalis 30g, Ligustrum lucidum 30g, Bear bile powder 1.0g, Licorice 15g

[0075] (2) Preparation method:

[0076] The preparation method is as follows: the eleven flavors in the recipe, except for the bear bile powder, the mylabris is crushed into a 60-mesh coarse powder, and the water is extracted 3 times, the first time is added with 20 times the amount of water, soaked for 40 minutes, extracted for 1.5 hours, the second, Add 15 times the amount of water each time for three times, extract for 1.0 hour, filter, combine the filtrate, add ethanol until the alcohol content reaches 80%, let it stand, filter, and concentrate the filtrate under reduced pressure to form a thick paste, add 8 times the amount of water, Stir, stand still, filter, the filtrate is centrifuged at a speed of 100...

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Abstract

The invention relates to applications of compound mylabris traditional Chinese medicine composition and preparations thereof in preparing drugs for curing depression, especially the drugs for curing tumor related depression. The compound mylabris traditional Chinese medicine composition is composed of eleven medicines such as mylabris, gen-seng, radix astragali, acanthopanax, sparganium, barbat skullcap, and the like. The compound mylabris preparation is prepared by adding corresponding auxiliary materials to the traditional Chinese medicine composition through conventional methods. The invention provides a novel drug for curing depression, and enlarges the clinical application of compound mylabris preparations.

Description

technical field [0001] The invention relates to a new application of compound mylabris traditional Chinese medicine composition and its preparation in preparing medicine for treating depression, especially the application in preparing medicine for treating depression of tumor patients. technical background [0002] Depression, belonging to affective disorders, is a group of psychological disorders or affective disorders caused by various reasons with depression as the main symptom. The clinical manifestations are depression, loss of interest, low self-evaluation, pessimism and disappointment about the future, Reluctance to take the initiative to interact with people, etc. It is often accompanied by corresponding changes in thinking and behavior. Some patients may experience hallucinations and delusions, and severe cases may be accompanied by suicidal behavior, which seriously affects people's quality of life. Most cases have a tendency to relapse, and most of each attack ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P25/24A61K35/413A61K35/64
Inventor 窦啟玲
Owner GUIZHOU YIBAI PHARMA CO LTD
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