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Composition for treating asthenic cold type migraine

A technology for migraine and a composition, which is applied in the field of medicines for treating migraine of deficiency-cold type, can solve the problems of unsatisfactory diagnosis and treatment of migraine, low control rate, high disability and the like, and achieves good treatment of migraine of deficiency-cold type. Effects of headache disorders

Active Publication Date: 2015-01-07
CAPITAL UNIVERSITY OF MEDICAL SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current diagnosis and treatment of migraine are still not ideal. The epidemiological "three highs and one low" characteristics of high incidence, high disability, high missed diagnosis rate and low control rate of migraine make it necessary for us to look for More effective migraine treatment drug
Currently, opioids, triptans, corticosteroids, non-steroidal anti-inflammatory drugs or anti-epileptic drugs are mostly used in the treatment of migraine clinically, but the application of these drugs will cause various diseases such as drug dependence side effects, so more and more attention has been paid to the research on the treatment of migraine with traditional Chinese medicine

Method used

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  • Composition for treating asthenic cold type migraine
  • Composition for treating asthenic cold type migraine
  • Composition for treating asthenic cold type migraine

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Embodiment 1

[0044] (1) Preparation of a composition for treating deficiency-cold migraine

[0045] Compositions 1 to 6 for treating deficiency-cold migraine were prepared according to the contents in Table 3.

[0046] The raw materials of each component of the composition of the present invention can be purchased through commercial channels or separated and extracted from ginseng and Evodia rutaecarpa by conventional high-performance liquid chromatography. In this example, rutaecarpicin was extracted from Evodia rutaecarpa by high performance liquid chromatography. For the method, see [Li Li, Jia Ying, Chen Xiaohui, etc. HPLC method for simultaneous determination of the contents of rutaecarpa and limonin in rutaecarpa (English)[ J]. China Natural Medicines, 2003, 1(3): 31-33]. The rest of the components are purchased through commercial channels.

[0047]Table 3 Contents of each component of each composition (μg·mL -1 )

[0048]

[0049] (2) Establishment of Deficiency-cold Migraine ...

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Abstract

Composition for treating the asthenic cold type migraine comprises ingredients as follows: 3.0-4.0 parts of ginsenoside Rb1 by weight and 1.0 part of evodiamine (Ev) by weight; preferably, 3.0-4.0 parts of the ginsenoside Rb1 by weight, 1.0 part of the Ev by weight, 0.15-0.60 part of rutaevine (Rv) by weight, 0.50-2.0 parts of limonin(Li) by weight; more preferably, 3.0-4.0 parts of the ginsenoside Rb1 by weight, 1.0 part of the Ev by weight, 0.15-0.60 part of Rv by weight, 0.50-2.0 parts of Li by weight, 0.60-4.0 parts of ginsenoside Rg1 by weight and 0.02-0.25 part of rutaecarpin (Ru). Essential ingredients, namely, the Rb1 and the Ev, which are effective in treating the asthenic cold type migraine, are provided, and main active ingredients, namely, the Rg1, the Rv, the Li and the Ru, are matched and combined on the basis, and the composition which has the optimum curative effect on the asthenic cold type migraine is determined.

Description

technical field [0001] The invention relates to a medicine for treating migraine of deficiency-cold type, in particular to a composition of active ingredients of traditional Chinese medicine for treating migraine of deficiency-cold type. Background technique [0002] Migraine is a multifactorial primary headache disorder characterized by unilateral, sharp, throbbing pain with headache as the main symptom. In 2001, the World Health Organization listed migraine as one of the most disabling chronic diseases. However, the current diagnosis and treatment of migraine are still not ideal. The epidemiological "three highs and one low" characteristics of high incidence, high disability, high missed diagnosis rate and low control rate of migraine make it necessary for us to look for More effective migraine treatments. Currently, opioids, triptans, corticosteroids, non-steroidal anti-inflammatory drugs or anti-epileptic drugs are mostly used in the treatment of migraine clinically, b...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61P25/06A61K31/519A61K31/585A61K31/365
CPCA61K31/519A61K31/585A61K31/704A61K2300/00
Inventor 龚慕辛许永崧潘学强
Owner CAPITAL UNIVERSITY OF MEDICAL SCIENCES
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