Disturbance-based intensity modulated arc therapy optimization method

An optimization method and intensity modulation technology, which is applied in X-ray/γ-ray/particle irradiation therapy, special data processing applications, instruments, etc., can solve problems such as influence of optimization results, long time, large amount of calculation, etc., to meet the requirements of optimization Effect requirements, meet the calculation time, optimize the effect of fast speed

Active Publication Date: 2015-01-28
HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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Problems solved by technology

This method can get results relatively quickly, but subfield segmentation will affect the optimization results, and will produce many complex subfield shapes, resulting in low treatment efficiency
The "one-step method" is similar to the direct sub-field segmentation in the static intensity modulation, and the radiotherapy plan that can be implemented is directly obtained through optimization, but it takes a long time to converge
[0004] Due to the extremely high complexity of the problem and the huge amount of calculation, it is necessary to meet the requirements of calculation time and optimization effect at the same time
There is no relevant literature report

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  • Disturbance-based intensity modulated arc therapy optimization method
  • Disturbance-based intensity modulated arc therapy optimization method
  • Disturbance-based intensity modulated arc therapy optimization method

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[0039] The present invention first establishes a rotating intensity modulation optimization model according to conditions such as target area and organ-at-risk information, beam setting parameters, dose (volume) constraints of each organ, and hardware constraints, and uses intensity distribution optimization to obtain initialization subfields. Then the shape of the subfield is optimized by perturbation, and the weight of the subfield is optimized by the conjugate gradient method after the shape is determined, and the optimal solution of the rotation intensity modulation is finally optimized. The invention not only accurately establishes the mathematical model of the optimization problem, but also has fast solving speed, stability and strong robustness.

[0040] Such as figure 1 As shown, the present invention is based on a disturbance-based rotary intensity modulation optimization method, and the specific implementation steps are as follows:

[0041] (1) The intensity distrib...

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Abstract

The invention provides a disturbance-based intensity modulated arc therapy optimization method. Firstly an intensity modulated arc therapy optimization model is established according to conditions such as information on a target region and organs at risk, beam setting parameters and each organ dose (volume) constraint and hardware constraint; an initialized sub-field is obtained by using intensity distribution optimization. Then the shape of the sub-field is optimized by using disturbance, the weight of the sub-field is optimized by using a conjugate gradient method after determination of the shape, and finally the optimal solution for the intensity modulated arc therapy is optimized. According to the method, a mathematical model of an optimization problem is accurately established, the solving speed is high, the algorithm is stable and the robustness is strong.

Description

technical field [0001] The invention relates to a disturbance-based rotary intensity modulation optimization method, which belongs to the technical field of intelligent calculation methods. Background technique [0002] Rotary intensity modulation is the most advanced intensity modulation technology currently developed, which can well avoid the disadvantage of long static intensity modulation treatment time, and at the same time, the treatment effect is better than static intensity modulation. There is no optimization process for the initial rotation intensity modulation, which is equivalent to the forward plan, that is, 360° is divided into several directions, and the shape of the subfield in each direction is determined according to the shape in the BEV. Later, the rotation intensity modulation optimization was developed, and some optimization methods were used to optimize the shape and weight of the subfields in each direction. However, the difficulty of the current rota...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00A61N5/10
Inventor 裴曦曹瑞芬胡丽琴吴宜灿
Owner HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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