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Electrochemical detection system

A detection system, electrochemical technology, applied in medical science, diagnostic recording/measurement, diagnosis, etc., can solve the problems of limited diffusion speed of dialysis membrane, inability to use neurotransmitter vesicle release event online detection, etc., to achieve long-term solution The effect of time-continuous detection

Active Publication Date: 2020-07-03
INST OF ELECTRONICS CHINESE ACAD OF SCI
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Problems solved by technology

However, due to the limitation of the diffusion rate of the dialysis membrane, the time resolution of microdialysis detection and analysis is on the order of minutes, which cannot be used for online detection of neurotransmitter vesicle release events on the order of milliseconds.

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  • Electrochemical detection system
  • Electrochemical detection system
  • Electrochemical detection system

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Embodiment Construction

[0027] In order to make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0028] It should be noted that, in the drawings or descriptions in the specification, the same drawing numbers are used for similar or identical parts. And in the drawings, the embodiments are marked for simplicity or convenience. Furthermore, elements or implementations not shown or described in the drawings are in the form known to those of ordinary skill in the art. Additionally, although examples of parameters including specific values ​​may be provided herein, the parameters need not be exactly equal to the corresponding values, but may approximate the corresponding values ​​within acceptable error tolerances or design constraints.

[0029] In an exemplary embodiment of the present invention, an...

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Abstract

The invention discloses an electrochemical detecting system, which comprises self-reference microelectrode arrays including a plurality of detection sties positioned at the parts to be detected. Reference signals and electrochemical response signals can be acquired simultaneously at the same detection site. An electrochemical surveymeter connected with the self-reference microelectrode arrays is to detect concentrations of chemical substance variation of a plurality of detection sties and output data. The electrochemical detecting system can resolve the problem of consecutively detecting rapid release of cerebral trace neurotransmitters for yonks for researches of neuroscience, and provide a novel research tool and means for researches of neuroscience.

Description

technical field [0001] The invention relates to the field of signal detection in the electrochemical industry, in particular to an electrochemical detection system. Background technique [0002] Neurotransmitters are a class of specific chemicals that generate signal transduction between neuronal chemical synapses. After they are synthesized in neurons, they are released from the presynaptic membrane and immediately bind to the corresponding postsynaptic membrane receptors to produce Complete the function of neural information transmission. Neurotransmitters are closely related to human health and play an important role in the regulation of physiological functions such as learning, memory, neuronal plasticity, body movement, and brain development. Therefore, it is of great significance to carry out the detection of neurotransmitter release in the living brain to understand the mechanism of brain operation, study the etiological mechanism of brain diseases, drug treatment an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00A61B5/05
CPCA61B5/05A61B5/4064A61B5/6847A61B5/6868A61B5/7203A61B5/7225A61B5/725A61B2503/40A61B2503/42
Inventor 徐声伟蔡新霞刘军涛王蜜霞宋轶琳罗金平徐辉任肖桂花张松
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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