Method for measuring depth of front surface of lamina cribrosa based on active contour and energy constraint

Abstract

The invention discloses a method for measuring the depth of the front surface of lamina cribrosa based on active contour and energy constraint. A Bruch's membrane opening point determination approachbased on K-means clustering and active contour and a lamina cribrosa front surface segmentation approach based on energy constraint are adopted. First, the clustering map of K-means clustering is taken as the initial contour of a C-V active contour model, and a Bruch's membrane opening point in the contour is extracted. Then, a region of interest segmented from the front surface of lamina cribrosais obtained according to the position of the opening point, and the front surface of lamina cribrosa is segmented out through an energy constraint approach. Finally, the depth of the front surface oflamina cribrosa is measured according to the structure of the two steps. The result of the invention is better than that of the existing method, and is consistent with the manual calibration result of experts. The problem that it takes time and energy for experts to measure the depth of the front surface of lamina cribrosa through manual calibration in clinical diagnosis is solved. The method isof positive significance to the early screening and clinical diagnosis of glaucoma.

Description

technical field [0001] The invention belongs to the technical field of image recognition and relates to a method for measuring the depth of the front surface of a sieve plate based on active contours and energy constraints. Background technique [0002] Glaucoma is the second leading cause of blindness in the world. It destroys the axons of optic ganglion cells around the optic nerve head, resulting in loss of vision. Due to the irreversibility of glaucoma, early detection, early detection and early treatment of glaucoma can slow down the progress of the disease. However, because the pathogenesis of glaucoma has not been fully clarified, the research on the risk factors of glaucoma is still a hot issue at present. [0003] The lamina cribrosa is located in the sclera, where the axons of retinal ganglion cells exit the eye. Pressure gradient between the outside of the eye. The anatomy of the cribriform plate is as follows: approximately 12,000–15,000 retinal ganglion cell ...

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Problems solved by technology

[0017] The present invention provides a method for measuring the depth of the front surface of the sieve plate based on active cont

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