Nasal obturator for mouse

Abstract

The invention provides a nasal obturator for a mouse. The nasal obturator comprises a main obturator body and thermal gel, the main obturator body comprises an obstruction segment, a limit segment anda clamping segment, and the main obturator body is of a u-shaped structure formed in the mode that the head and tail of a stainless steel wire are aligned and folded and one end is bent; the head andtail of the stainless steel wire are aligned and folded to form a first steel wire segment and a second steel wire segment, the tail of the second steel wire segment is upwards bent by 90 degrees toform the limit segment, and the tail, protruding out of the limit segment, of the first steel wire segment is the clamping segment; a superposed steel wire bending segment above the limit segment andthe clamping segment is the obstruction segment, and the thermal gel wraps the obstruction segment. According to the nasal obturator for the mouse, convenience is provided for establishment of a bilateral intermittent mouse nasal obstruction animal model and physiopathologic research on mouth breathing.

Description

technical field [0001] The invention relates to an experimental appliance, in particular to a rat nasal blocker used for establishing a rat bilateral intermittent nasal blockage model in scientific research. Background technique [0002] The normal breathing pattern of the human body is nasal breathing, and when the nasal airway is blocked, the human body will adaptively change the nasal breathing pattern to the mouth breathing pattern. Mouth breathing is a common bad breathing habit in clinical practice, which will lead to abnormal pressure on the oral and maxillary system during growth and development, destroying the normal balance of muscle strength and occlusal force, resulting in the development of dental arch, alveolar bone and jaw. abnormal shape. [0003] As an experimental animal with relatively simple source and feeding conditions, rats are ideal experimental animals for establishing nasal obstruction models due to their single genetic background and short growth ...

AI Technical Summary

Problems solved by technology

[0004] However, the above-mentioned methods all produce relatively large nasal mucosal trauma, which not only introduces more interference factors (trauma, infection, etc.), but also affects the survival rate of rats; moreover, most of the cases of mouth breathing in clinical practice are caused by the nasal airway during night sleep. Aggravated obstruction with obvious mouth breathing and normal nasal ventilation during the day, not continuous obstruction for 24 hours

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