The invention relates to the technical field of a wire stripping machine, in particular to a full-automatic coaxial wire stripping machine. The full-automatic coaxial wire stripping machine comprises a case body, wherein a control unit is arranged in the case body; and a feeding alignment unit, a rotary-cut unit, a first wire feeding stripping unit, an automatic demising mechanism, a cutting and stripping unit and a second wire feeding stripping unit are sequentially arranged on the case body in a coaxial wire moving direction. The full-automatic coaxial wire stripping machine has functions of alignment, cutting off wires and both-end peeling. According to parameters including diameters of coaxial wires, thickness of each layer, set lengths of wire sections, stripping length of each layer and the like, the work of wire feeding, alignment, rotary cut, cutting off and both-end peeling can be automatically and quickly realized, and the wire stripping speed can be controlled according to the operation speed of each drive motor, so that the degree of automation of the full-automatic coaxial wire stripping machine can be greatly improved, and production efficiency can be greatly improved.