A kind of traditional Chinese medicine compound preparation for treating viral myocarditis in children and its preparation process

Abstract

The invention relates to a traditional Chinese medicine compound preparation for treating children with viral myocarditis and a preparation process thereof, belonging to the technical field of medical application of effective parts of traditional Chinese medicines. The technical scheme is: grind American ginseng into coarse particles, add ethanol and heat and reflux for extraction 3 times, the extracted filtrate is concentrated with a rotary evaporator, and the concentrated filtrate is extracted with petroleum ether and water-saturated n-butanol for 3 times, and the above Use a rotary evaporator to recover the n-butanol in the supernatant, evaporate the remaining medicinal liquid in a water bath, concentrate it, and dry it in a drying cabinet to obtain the total saponins of Panax ginseng; The saponin preparation method is the same as above; the configuration ratio of each component: the configuration mass ratio of total saponins of Panax ginseng, total saponins of Astragalus, total saponins of Cortex Moutan, and total saponins of Wangbuliuxing is 6:6:4:1. The raw material medicine of the invention has wide sources and low cost; the medicinal effect is remarkable, safe and non-toxic; the dosage is small, which is convenient for children to take; and the medicine is taken orally and is convenient for storage.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating viral myocarditis in children and a preparation process thereof, especially for myocardial tissue damage and myocardial cell apoptosis caused by Coxsackie virus B (CVB) in enteroviruses. The application of the invention belongs to the technical field of medical application of effective parts of traditional Chinese medicines. Background technique [0002] Viral myocarditis (VMC) refers to localized or diffuse acute or chronic inflammatory lesions of the myocardium caused by viral infection, and belongs to infectious myocardial disease. VMC has a wide range of people, and it is more common in preschool and school-age children. Most of them are caused by enteroviruses and respiratory viruses. Coxsackievirus A, Coxsackievirus B (CVB), Eikevirus, and poliovirus are common myocarditis-causing viruses, among which CVB is the most important pathogen, accounting for about...

AI Technical Summary

Problems solved by technology

Western medicine treatment is mainly aimed at the symptomatic treatment of viral infection and myocardial inflammation. There are limited types of clinically available symptomatic therapeutic drugs for pediatric patients. Currently, free radical scavengers are mostly used in clinical practice, such as intravenous or oral vitamin C, coenzyme Q10, vitamin Bco , ATP, inosine, cyclic adenosine, cytochrome C, glucocorticoids, etc., but the treatment effect is not ideal, often have different degrees of adverse reactions, and the price is expensive

Although Chinese medicine literature has recorded many compound prescriptions to treat this disease, the curative effect is not good, and the clinical application dose is relatively large, especially there are shortcomings of large doses of traditional Chinese medicine taken by children and difficulty in application, and its mechanism of protecting the myocardium needs further research and confirmation, so It is particularly urgent to study the effective components of traditional Chinese medicine for the treatment of refractory diseases

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