Prognostic indicators of poor outcomes in PRAEGNANT metastatic breast cancer cohort

A metastatic breast cancer, poor technology, applied in genomics, proteomics, health index calculation, etc., can solve the problem of lack of good understanding of molecular characterization of metastatic breast cancer, unfavorable prognosis of patients, poor prognosis and predictive factors good understanding etc.
CN110770849AInactive Publication Date: 2020-02-07NANTOMICS LLC
0 Cites 4 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANTOMICS LLC
Publication Date
2020-02-07
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Transcriptomics data from tumor tissue of patients diagnosed with metastatic breast cancer are clustered and associated with overall survival of the patients. A subset of genes from one of the clusterassociated with poor outcome are used to generate a survival prediction model predicting a survival time based on expression levels of a plurality of genes. Using such generated survival prediction model, a survival time of a patient diagnosed with metastatic breast cancer can be predicted and a treatment regimen can be updated or generated based on the survival time.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] This application claims priority to our co-pending U.S. Provisional Applications Serial Nos. 62 / 521,267, filed June 16, 2017 and 62 / 594,345, filed December 4, 2017. technical field

[0002] The field of the invention is systems and methods for identifying molecular profiles of metastatic breast cancer that can be used to predict prognosis and / or survival of patients with metastatic breast cancer. Background technique

[0003] All publications and patent applications herein are incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. To the extent that a definition or usage of a term in an incorporated reference is inconsistent or contrary to the definition of that term provided herein, the definition of that term provided herein applies and not the definition of that term in that reference.

[0004] After first diagnosis, breast cancers are typicall...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More