Human milk fortifier

A technology of human milk fortifier and human milk oligosaccharide, which is applied in the field of human milk fortifier composition, can solve problems such as unclearness and increased risk

Pending Publication Date: 2020-04-17
SOC DES PROD NESTLE SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The reason for this increased risk is unclear

Method used

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  • Human milk fortifier
  • Human milk fortifier
  • Human milk fortifier

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0127] longitudinal clinical trial :

[0128] The inventors designed a longitudinal study of milk sampling in lactating mothers at 2 days (V1), 17 days (V2), 30 days (V3), 60 days (V4), 90 days (V5) and 120 days (V6) postpartum. Clinical Trials. Quantitative analysis of HMOs in milk samples.

[0129] The data presented here are from a multicentre exploratory study whose primary purpose was to characterize key nutritional components in human breast milk. Healthy women of all ethnicities who were in the last trimester of pregnancy and who were scheduled to exclusively breastfeed infants from birth to 4 months of age were recruited and the infants were followed until 4 months of age.

[0130] Breast milk samples were collected from mothers on the following days postpartum: 0 to 3 days (V1), 17±3 days (V2), 30±3 days (V3), 60±5 days (V4), 90±5 days (v5 ) and 120±5 days (v6). Samples were collected using a breast pump (Symphony Breastpump, Medela) by adequate compression of o...

Embodiment 2

[0164] Table XXX lists human milk fortifier compositions according to the present invention. The human milk fortifier can be used to supplement breast milk produced by mothers of multiple births for infants under one month old.

[0165]

[0166]

[0167]

[0168] Table XXX

[0169] The compositions according to the invention may be varied in a number of ways without departing from the scope of the invention as defined in the claims. HMO per 100 kcal was calculated based on the assumption that the composition has an energy value of 670 kcal / liter.

Embodiment 3

[0171] Table XXXI lists HMO human milk fortifier compositions according to the invention. The human milk fortifier can be used to supplement breast milk produced by mothers of multiple births for infants under one month old. The human milk fortifier is presented in single-dose stick packs, for addition to, for example, 100 mL of expressed breast milk.

[0172] HMOs mg / g 3'-sialyllactose 6 disialyllactose-N-tetraose 25 Fucosyllactose-N-hexose III 10 lactose-N-hexose A 12 Lactose-N-neofucosylpentose 4 lactose-N-neotetraose 30 lactose 911

[0173] Form XXXI

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PUM

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Abstract

The invention discloses a human milk fortifier composition comprising one or more human milk oligosaccharide. Said human milk fortifier composition may be tailored to fortify the breastmilk of a multiparous woman.

Description

technical field [0001] The present invention relates to a human milk fortifier composition, more particularly to a human milk fortifier composition comprising human milk oligosaccharides. In particular the present invention relates to a human milk fortifier composition specially formulated to fortify the breast milk of a multiparous woman and to be used as a human mother's supplement for consumption by infants or children who are offspring of multiparous mothers. The invention also relates to the use of said milk enhancer composition. Background technique [0002] Babies who are the offspring of multiple birth females are considered to be at increased risk for various health problems during infancy, childhood and later life. The reason for this increased risk is unclear. However, given that the family size of two children is the most common family size in many countries, and given that the most common family size is even larger in many countries, it is necessary to identif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/702A61P1/00A23L33/00A23L33/10
CPCA61K31/702A23L33/40A23L33/10A61P1/00A23L33/20A23L33/125
Inventor T·M·塞缪尔A·比尼亚N·斯普伦格
Owner SOC DES PROD NESTLE SA
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