A rodent depression modeling device and experimental system

Abstract

A rodent depression modeling device and experimental system, relating to the technical field of animal experiment methods and equipment, including a cage and a control mechanism, the cage is provided with several cages, and the cages are fixed and connected There is a cage body for containing experimental animals, a vibrating motor is provided under the cage, the top of the vibrating motor is connected to the bottom of the cage through a vibrating spring, and an electric telescopic rod is also provided on the upper part of the back of the cage , the fixed end of the electric telescopic rod is hinged with the wall, the telescopic end of the electric telescopic rod is hinged with the back of the cage, the control mechanism is equipped with an electric control cabinet, and the electric telescopic rod and the vibration motor are connected with the electric control cabinet electrical connection. The invention can ensure the consistency, simultaneity and timing of the experimental operation, can minimize the operation steps of the experimenters, greatly improve the work efficiency, and improve the experiment quality, so that the depression modeling can be completed efficiently and smoothly.

Description

technical field [0001] The invention relates to the technical field of animal experiment methods and equipment, in particular to a rodent depression modeling device and an experiment system. Background technique [0002] Chronic Unforeseen Stress (CUMS) depression model is an effective animal depression model. The stress process of CUMS includes alternating short-term stress and long-term stress. Stress mainly includes: deprivation of drinking water, deprivation of food, 45° tilt, staying overnight in humidity, turning off lights, strobe lights, continuous light, white noise, heat stress in a 42°C oven, shaking stress, empty bottle stimulation (dumping out drinking water) ), odor stimulation, foreign body stimulation (also tail clamping, ice water swimming, crowding, etc.), the stress stimulation was carried out continuously for 35 days. During the experiment, the rats received two different stress stimuli every day as planned, and the sugar preference of the rats was dete...

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Problems solved by technology

[0003] At present, there is no depression modeling device, and all experimental operations need to be carried out manually. At the same time, it is necessary to purchase a variety of equipment, but it is still impossible to form an experimental system for simultaneous use. There are complex operations, low efficiency, and poor experimental stability. Long, unsatisfactory results, high cost and other defects

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