Application of beta-nicotinamide mononucleotide (NMN) in products for preventing alopecia or promoting hair growth

A hair growth and single nucleotide technology, applied in medical preparations containing active ingredients, food science, organic active ingredients, etc., can solve the problems of hair loss, hair loss, poor treatment effect, side effects, etc.

Inactive Publication Date: 2020-08-28
WUXI MAGTEIN BIOMEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] The invention provides the application of β-nicotinamide mononucleotide in products for preventing hair loss or pro

Method used

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  • Application of beta-nicotinamide mononucleotide (NMN) in products for preventing alopecia or promoting hair growth
  • Application of beta-nicotinamide mononucleotide (NMN) in products for preventing alopecia or promoting hair growth
  • Application of beta-nicotinamide mononucleotide (NMN) in products for preventing alopecia or promoting hair growth

Examples

Experimental program
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Effect test

Embodiment

[0020] 1. Materials:

[0021] 1. Animal: SPF grade male mouse, weighing 18-20g

[0022] 2. Sample: NMN (β-nicotinamide mononucleotide)

[0023] 3. Instruments: Olympus microscope, electron microscope, SLR camera

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Abstract

The invention discloses an application of beta-nicotinamide mononucleotide (NMN) in products for preventing alopecia or promoting hair growth, and relates to the technical field of products for preventing alopecia or promoting hair growth. Research results show that mice in a control group and mice in a test group have no significant difference in weight in a whole test period, and the growth condition of the mice is good, which illustrates that the NMN has no toxic or side effect; compared with a blank group and a model group, after 8 weeks of high-dose intragastric administration, the hair of the mice grows more densely, the numbers of corium layer hair follicles in hair removal areas of the high-dose group are slightly reduced, the structures of residual hair follicles are basically complete, sebaceous glands are slightly reduced, but the improvement of the low-dose group is not obvious, and thus it is suggested that the NMN can promote hair growth of the depilated mice.

Description

technical field [0001] The invention relates to the technical field of products for preventing hair loss or promoting hair growth, in particular to the application of β-nicotinamide mononucleotide in products for preventing hair loss or promoting hair growth. Background technique [0002] β-nicotinamide mononucleotide (NMN) full name nicotinamide mononucleotide, nicotinamide mononucleotide, is a naturally occurring biologically active nucleotide, NMN has two irregular forms, α and β; β The isomer is the active form of NMN with a molecular weight of 334.221 g / mol. Widely distributed in daily food, vegetables such as cauliflower (0.25–1.12mg NMN / 100gm) and Chinese cabbage (0.0–0.90mg NMN / 100gm), fruits such as avocado (0.36–1.60mg NMN / 100gm), tomatoes (0.26– 0.30mg NMN / 100gm), meat such as raw beef (0.06–0.42mg NMN / 100gm) are rich in NMN. [0003] NMN is the precursor of NAD+, and its function is mainly reflected by NAD+. The specific physiological reactions that NAD+ partic...

Claims

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Application Information

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IPC IPC(8): A61K31/706A61P17/14A61P17/00A23L33/13
CPCA61K31/706A61P17/14A61P17/00A23L33/13A23V2002/00
Inventor 吴长泉
Owner WUXI MAGTEIN BIOMEDICAL TECH CO LTD
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