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Application of turnip acidic polysaccharide BRAP-2

A technology of BRAP-2 and acidic polysaccharides, which is applied in the field of biomedicine and achieves the effect of broad clinical application prospects

Pending Publication Date: 2020-12-18
XINJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is currently no polysaccharide drug that can prevent lung cancer

Method used

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  • Application of turnip acidic polysaccharide BRAP-2
  • Application of turnip acidic polysaccharide BRAP-2
  • Application of turnip acidic polysaccharide BRAP-2

Examples

Experimental program
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Embodiment 1

[0017] The application of the turnip acidic polysaccharide BRAP-2 in this example, in this application, the turnip acidic polysaccharide BRAP-2 can treat Lewis lung cancer in mice by activating the TLR4 signaling pathway;

[0018] The node proteins of the TLR4 signaling pathway are MyD88, TRAF6, JNK, C-jun, P-C-jun, p65.

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Abstract

The invention provides an application of turnip acidic polysaccharide BRAP-2. The turnip acidic polysaccharide BRAP-2 is used for treating mouse Lewis lung cancer by activating a TLR4 signal path. Theturnip acidic polysaccharide BRAP-2 plays an important role in treating the mouse Lewis lung cancer, has a wide clinical application prospect, and provides a new target for clinical development of drugs for treating lung cancer.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of a turnip acidic polysaccharide BRAP-2. Background technique [0002] Lung cancer is one of the malignant tumors with the fastest growing morbidity and mortality and the greatest threat to human health and life. In the past 50 years, many countries have reported that the morbidity and mortality of lung cancer have been increasing. Malignant tumors that cause relatively high mortality every year include: lung cancer, gastric cancer, liver cancer, colon cancer, and breast cancer. Among them, lung cancer has become the malignant tumor with the highest morbidity and mortality rate in the world. The annual number of new lung cancer cases worldwide has reached 1.6 million, and deaths The number has reached 1.4 million. Currently there is no polysaccharide drug that can prevent lung cancer. Contents of the invention [0003] The technical problem t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61K36/31A61P11/00A61P35/00
CPCA61K31/715A61K36/31A61P11/00A61P35/00
Inventor 海力茜·陶尔大洪常军民马晓丽阿依夏古丽·巴卡斯康金森周凯杨飞李玲沈琪庞国凤李亚童乔丽洁李欢欢阿吉然·阿布拉
Owner XINJIANG MEDICAL UNIV
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