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Ophthalmic composition for suppressing degradation of soft contact lens

A technology of soft contact lenses and compositions, which can be used in drug combinations, glasses/protective glasses, glasses/goggles, etc., and can solve the problems of pollen outer wall rupture and achieve the effect of inhibiting deterioration

Pending Publication Date: 2021-06-15
SANTEN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] According to Non-Patent Document 4, it is taught that additives contained in eye drops may also have an effect on the rupture of pollen exine, the dissolution of allergens, for example, PBS (phosphate-buffered saline) may promote the rupture of pollen exine

Method used

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  • Ophthalmic composition for suppressing degradation of soft contact lens
  • Ophthalmic composition for suppressing degradation of soft contact lens
  • Ophthalmic composition for suppressing degradation of soft contact lens

Examples

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Embodiment

[0170] Although formulation examples and test examples are shown below, these are for better understanding of the present invention and do not limit the scope of the present invention.

[0171] Preparation example

[0172] Representative formulation examples of the present invention are shown below. In addition, in the following formulation examples, the compounding quantity of each component is the content in 100 mL of formulations.

preparation example 1

[0174]

preparation example 2

[0176]

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Abstract

The present invention provides: an ophthalmic composition which has an effect of suppressing the degradation of a soft contact lens, the ophthalmic composition containing a boric acid or a salt thereof and an epinastine or a salt thereof; and a pollen rupture inhibitor containing a specific concentration of a boric acid or a salt thereof and an epinastine or a salt thereof.

Description

technical field [0001] The present invention relates to an ophthalmic composition containing boric acid or a salt thereof and epinastine or a salt thereof for suppressing deterioration of soft contact lenses. It also relates to a pollen break inhibitor containing boric acid or a salt thereof and epinastine or a salt thereof in a concentration of 0.01 to 2% (w / v) of the boric acid or a salt thereof. Background technique [0002] Ophthalmic compositions containing solvents such as water, which are expected to be used repeatedly, require more than a certain level of anti-corrosion measures in order to prevent the growth of fungi and the like. Therefore, such an ophthalmic composition usually contains a preservative. For example, in the case of eye drops, benzalkonium chloride is often used as a preservative. Benzalkonium chloride is water-soluble, chemically stable, and has high antiseptic efficacy compared with other preservatives. However, benzalkonium chloride is known to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/55A61P27/02A61P27/14G02C7/04A61K9/08A61K47/02A61K47/18
CPCA61K9/08A61K31/55A61K47/02A61K47/18A61P27/02A61P27/14G02C7/04G02C13/00
Inventor 森本隆司稻垣孝司小川敏弘桃川雄介
Owner SANTEN PHARMA CO LTD
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