Freezing low-temperature ball-milling preparation method of polylactic acid soft tissue filled micro rice grains

A technology of low-temperature ball milling and polylactic acid, which is applied in the direction of making medicines into special physical or ingestible devices, grain processing, etc., which can solve the problems of inconvenient promotion, cumbersome preparation of polylactic acid, and inability to meet the needs of the cosmetic and plastic surgery industry. , to achieve the effect of reducing production difficulty and improving refinement

Pending Publication Date: 2021-09-07
青岛杰圣博生物科技有限公司
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Problems solved by technology

[0003] In order to solve the problems raised in the above-mentioned background technology, the object of the present invention is to provide a method for preparing polylactic acid soft tissue filled micro-particles by freezing and low-temperature ball milling, which

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  • Freezing low-temperature ball-milling preparation method of polylactic acid soft tissue filled micro rice grains

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Embodiment Construction

[0022] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0023] Such as figure 1 As shown, the present invention provides a method for preparing polylactic acid soft tissue filled micro-particles by freezing and cryogenic ball milling, comprising the steps of: step a) subpackaging; step b) freezing; step c) grinding; step d) sorting; step e) configuration solution; step f) mixing; step g) freeze-drying;

[0024] Step a) Packing: Weigh a certain amount of polylactic acid raw material particles, place the above-menti...

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Abstract

The invention discloses a freezing low-temperature ball-milling preparation method of polylactic acid soft tissue filled micro rice grains. The freezing low-temperature ball-milling preparation method comprises the following steps: step a) sub-packaging; step b) freezing; step c) grinding; step d) sorting; step e) solution preparation; step f) mixing; and step g) freeze drying. The step a) sub-packaging comprises weighing a certain amount of polylactic acid raw material particles, placing the materials in a ball-milling tank, adding milling balls and sealing a cover, and the step b) freezing comprises placing the ball-milling tank filled with resin particles in a liquid nitrogen tank, and placing the liquid nitrogen tank in a refrigerator. The polylactic acid raw material particles are sub-packaged, ground and sorted, and the treated polylactic acid is improved by freezing and mixing, so that the refinement of the polylactic acid production step can be improved, the production difficulty can be reduced, and the problems that the existing polylactic acid preparation mode is relatively complicated and inconvenient to popularize, and the use requirements of the existing cosmetic and plastic surgery industry cannot be met are solved.

Description

technical field [0001] The invention relates to the technical field of cosmetic medicines, in particular to a method for preparing polylactic acid soft tissue filled micron particles by freezing and low-temperature ball milling. Background technique [0002] Now the plastic surgery industry uses hyaluronic acid the most, but the disadvantage of hyaluronic acid is that it does not last long and is usually absorbed by the human body 6-12 months after injection, so some plastic surgery companies choose to use polylactic acid injections to stimulate stimulation. Collagen regeneration in the deep layer of the face, but the existing polylactic acid preparation method is relatively cumbersome, not easy to promote, and unable to meet the needs of the existing cosmetic and plastic surgery industry. Contents of the invention [0003] In order to solve the problems raised in the above-mentioned background technology, the object of the present invention is to provide a method for prep...

Claims

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Application Information

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IPC IPC(8): A61J3/02B02C17/10
CPCA61J3/02B02C17/10
Inventor 金桥张双
Owner 青岛杰圣博生物科技有限公司
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